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Clinical Practice Guideline for Frailty Applicable in Primary Care Setting

You HS, Kwon YJ, Kim S, Kim YH, Kim Ys, Kim Y, Roh Yk, Park B, Park YK, Park CH, Son JS, Shin J, Shin HY, Oh B, Lee Jw, Shim JY, Won CW, Yoo JW, Lee SH, Kang HT, Lee DC

With aging becoming a global issue, the interest in healthy aging has increased as well. Healthy aging focuses on maintaining the functions and wellbeing of the elderly rather than merely...
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Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease

Kim IY, Park YK, Song SH, Seong EY, Lee DW, Bae SS, Lee SB

Background/Aims: Acute kidney injury (AKI) is an underestimated yet important risk factor for the development of chronic kidney disease (CKD), characterized by tubulointerstitial fibrosis and tubular dedifferentiation. Tubular dedifferentiation, which...
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Association between Depression and hs-CRP Blood Levels in Korean Adults: Using the National Health and Nutrition Survey 2018

Ahn MH, Eom YJ, Park YK

Background: In previous studies, C-reactive protein (CRP), interleukin (IL)-6, and IL-1 increased in depressed patients. Experimental and clinical evidence has reported that inflammatory mediators can induce symptoms of depression. Therefore,...
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Interleukin 1β Up-Regulates mRNA Expression of Inducible Nitric Oxide Synthase in 3T3-L1 Preadipocytes: Role of JAKs/STATs, PKCs, and Src

Park YK, Wang S, Jang BC

Recent evidence suggests obesity as a low or systemic chronic inflammation. (Pre)adipocytes in the adipose tissue (AT) express and secrete a variety of cytokines and adipokines. Inducible nitric oxide synthase...
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Flow diversion via telescoping stent with Low-profile Visualized Intraluminal Support Junior for treatment of ruptured dissecting aneurysm located at proximal posterior inferior cerebellar artery

Shin HK, Koo HW, Sohn MJ, Park YK

Dissecting aneurysm involving the posterior inferior cerebellar artery (PICA) are challenging because of its nature and anatomic relationship to medulla and lower cranial nerve. We introduce a case of ruptured...
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Parosteal Lipoma Associated with a Growing Osteochondroma of the Right Ilium

Myung MJ, Park JS, Ryu KN, Park YK, You MW, Baek JH

Parosteal lipoma is a rare type of lipoma, the incidence being approximately 0.3% of all lipomas. Moreover, parosteal lipoma coexisting with osteochondroma is extremely rare. A few cases with coexistence...
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A Pilot Clinical Study of Ocular Prosthesis Fabricated by Three-dimensional Printing and Sublimation Technique

Kim BR, Kim SH, Ko J, Baek SW, Park YK, Kim YJ, Yoon JS

Purpose: We sought to evaluate the safety and effectiveness of patient-specific ocular prostheses produced by three-dimensional (3D) printing and the sublimation technique. A comparison with prostheses produced using manual manufacturing...
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The Effect of Dementia Prevention Nutrition Program Using MIND Diet on the Changes in Cognitive Function of the Elderly with High-Dementia Risks

Song J, Choi SH, Hong CH, Jeong JH, Moon SY, Na HR, Park HK, Park YK

This study examined the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet of the Korean multi-domain dementia prevention program on the cognitive functions of the elderly with dementia...
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Effectiveness of nutrition education intervention focusing on fruits and vegetables in children aged six years and under: a systematic review and meta-analysis

An S, Ahn H, Woo J, Yun Y, Park YK

Purpose: A systematic review and meta-analysis of nutrition educational intervention studies was performed to assess the association between nutrition education intervention and fruit & vegetable (F&V) preferences and nutrition knowledge...
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Sternal Resection and Reconstruction for Solitary Plasmacytoma of the Sternum: Case Report

Choi CW, Park YK, Shin HK, Lim JW, Her K

A 63-year-old patient was admitted with a sternal fracture and mass. On evaluation, most of the body of the sternum had been destroyed by a tumor. Radical resection of the...
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A New Classification for Cervical Ossification of the Posterior Longitudinal Ligament Based on the Coexistence of Segmental Disc Degeneration

Lee JK, Ham CH, Kwon WK, Moon HJ, Kim JH, Park YK

Objective : Classification systems for cervical ossification of the posterior longitudinal ligament (OPLL) have traditionally focused on the morphological characteristics of ossification. Although the classification describes many clinical features associated...
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Recent Research and Knowledge on Treatment for Hepatitis B

Lee Hw, Choi Y, Park YK

Hepatitis B virus (HBV) infection is a major public health problem, with some 250 million people currently at high risk of developing chronic liver diseases. The current antiviral treatment for...
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Overview of anti-Hepatitis B virus agents

Lee Hw, Park Yk, Choi Y

Since the first FDA approval of Lamivudine in 1998, many nucleo(t)side analogs such as Lamivudine, Adefovir, and Entecavir have been used. However, they only inhibit DNA synthesis, and if their...
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Association between Insufficient Physical Activity and Hearing Loss in Korean Adults

Park YK, Jo YS, Yook JH, Park CJ, Yoo NR, Lim JH, Jeon MS, Park YK

Background: Insufficient physical activity is a major risk factor for cardiovascular disease, and some studies report relationship between physical activityand hearing. We aimed to analyze association between hearing loss and...
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Coronavirus Disease (COVID-19) Outbreak and Its Impact on Spinal Daily Practice : Preliminary Report from a Single (Regional) University Hospital in Republic of Korea

Ham CH, Moon HJ, Kim JH, Park YK, Lee TH, Kwon WK

Objective : Since the first discovery of the 2019 novel coronavirus (COVID-19), rapid and wide spread of the disease has been reported and the World Health Organization announced that a...
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Frequency of Eating Alone and Health Related Outcomes in Korean Adults: Based on the 2016 Korea National Health and Nutrition Examination Survey

Ahn JH, Park YK

Eating alone has recently become a very common dietary pattern in modern society. This study investigated the relationship between the frequency of eating alone and health related issues including chronic...
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Physicians' Difficulties Due to Patient Safety Incidents in Korea:a Cross-Sectional Study

Pyo J, Choi EY, Lee W, Jang SG, Park YK, Ock M, Lee SI

Background: Medical professionals who experience patient safety incidents (PSIs) are vulnerable to emotional pain and other difficulties; such individuals are referred to as “second victims.” This study quantitatively examines the...
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South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention in At-Risk Elderly People: Protocol of a Multicenter, Randomized Controlled Feasibility Trial

Park HK, Jeong JH, Moon SY, Park YK, Hong CH, Na HR, Song HS, Lee SM, Choi M, Park KW, Kim BC, Cho SH, Chun BO, Choi SH

Background and Purpose The prevalence of dementia is increasing in South Korea. Multidomain interventions may be useful for preventing dementia. Such programs need to be disseminated to elderly Koreans throughout the...
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Nutrient intakes and medication use in elderly individuals with and without dry mouths

Lee KA, Park JC, Park YK

BACKGROUND/OBJECTIVES: The nutrition of the elderly depends on various factors. Oral health, especially oral dryness, can be an important risk factor. In this study, we attempted to determine whether dry...
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BaSDAS: a web-based pooled CRISPR-Cas9 knockout screening data analysis system

Park YK, Yoon BH, Park SJ, Kim BK, Kim SY

We developed the BaSDAS (Barcode-Seq Data Analysis System), a GUI-based pooled knockout screening data analysis system, to facilitate the analysis of pooled knockout screen data easily and effectively by researchers...
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