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Diagnostic Efficacy of Serum Mac-2 Binding Protein Glycosylation Isomer and Other Markers for Liver Fibrosis in Non-Alcoholic Fatty Liver Diseases

Jang SY, Tak WY, Park SY, Kweon YO, Lee YR, Kim G, Hur K, Han MH, Lee WK

Background: Mac-2 binding protein glycosylation isomer (M2BPGi) has been established as a non-invasive biomarker for liver fibrosis. We evaluated the diagnostic efficacy of M2BPGi compared with those of other liver...
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Autophagy-Related Protein MAP1LC3C Plays a Crucial Role in Odontogenic Differentiation of Human Dental Pulp Cells

Cho HS, Park SY, Kim SM, Kim WJ, Jung JY

BACKGROUND: Autophagy plays important roles in odontogenic differentiation of dental pulp cells (DPCs) in the developmental stage of tooth bud. Few studies have reported the role of autophagy during reparative...
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Selective inhibition of V600E-mutant BRAF gene induces apoptosis in thyroid carcinoma cell lines

Park KS, Saindane M, Yang EY, Jin T, Rallabandi HR, Heil A, Nam SE, Yoo YB, Yang JH, Kim JB, Park SY, Park WS, Youn YK

Purpose: Papillary thyroid cancer (PTC) has a high incidence of BRAF V600E mutation. The purpose of this study was to evaluate the potential relationship between thyroiditis and BRAF ...
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Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea 2020

Jung HK, Kang SJ, Lee YC, Yang HJ, Park SY, Shin CM, Kim SE, Lim HC, Kim JH, Nam SY, Shin WG, Park JM, Choi IJ, Kim JG, Choi M, Korean College of Helicobacter and Upper Gastrointestinal Research

Helicobacter pylori infection is one of the most common infectious diseases worldwide. Although the prevalence of H. pylori is gradually decreasing, approximately half of the world's population still becomes infected...
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Etiology, Characteristics, and Outcomes of Community-Onset Pyomyositis in Korea: A Multicenter Study

Kim T, Park SY, Kwak YG, Jung J, Kim MC, Choi SH, Yu SN, Hong HL, Kim YK, Park SY, Song EH, Park KH, Cho OH, Choi SH, TKSSG

Background: Pyomyositis (PM) is a serious soft tissue infection and despite its clinical importance, previous studies have not been able to fully determine the clinical characteristics and microbial epidemiology of...
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Machine-Learning-Based Approach to Differential Diagnosis in Tuberculous and Viral Meningitis

Jeong YS, Jeon M, Park JH, Kim MC, Lee E, Park SY, Lee YM, Choi S, Park SY, Park KH, Kim SH, Jeon MH, Choo EJ, Kim TH, Lee MS, Kim T

Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis, but differentiating between the diagnosis of TBM and viral meningitis (VM) is difficult. Thus, we have developed machine-learning modules...
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Oleanolic Acid Protects the Skin from Particulate Matter-Induced Aging

Kim YJ, Lee JE, Jang HS, Hong SY, Lee JB, Park SY, Hwang JS

The role of particulate matter (PM) in health problems including cardiovascular diseases (CVD) and pneumonia is becoming increasingly clear. Polycyclic aromatic hydrocarbons, major components of PM, bind to aryl hydrocarbon...
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Simple Sugar Intake in Diabetics and Non-Diabetic Patients Who Visit Primary Care Clinic

Park SY, Moon GB, Kim YS, Kim SH

Background: Several studies have analyzed the relationship between sugar-sweetened beverages and the risk of diabetes mellitus (DM) in other countries. However, only few studies have assessed the relationship between sugar...
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Risk of Hospitalization by Multimorbidity in Middle-Aged Adults Using the 2013–2015 Korea National Health and Nutrition Examination Survey

Park SY, Lee ES, Yang YJ, Yoon YS, Lee JH, Huh Y, Park WJ, Cheon JM, Mun JW

Background: Rapidly growing older population and recent lifestyle changes has led to increased prevalence of chronic diseases. Previous studies have shown that multimorbidity has been linked to greater health care...
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Clinical utilization of long-acting granulocyte colony-stimulating factor (pegfilgrastim) prophylaxis in breast cancer patients with adjuvant docetaxel-cyclophosphamide chemotherapy

Jeon YW, Lim ST, Gwak H, Park SY, Shin J, Han HS, Suh YJ

Purpose: Treatment with 4 cycles of docetaxel and cyclophosphamide (TC) in the adjuvant setting is associated with better outcomes than treatment with doxorubicin and cyclophosphamide (AC). However, Western guidelines have...
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Diffuse-Type Tenosynovial Giant Cell Tumor of the Tendon Sheath in Both Wrists

Heo S, Park SY, Seo J, Koh SH, Lee IJ

Diffuse-type tenosynovial giant cell tumor (D-TSGCT), previously known as pigmented villonodular synovitis, is a locally aggressive neoplasm that may arise from the synovium, bursa, or tendon sheath. D-TSGCT is usually...
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Clinical Features and Radiological Differential Diagnoses of Symptomatic Sesamoid Bones and Accessory Ossicles: A Pictorial Essay

Kim HG, Ghoi HY, Park JS, Ryu KN, Park SY, Jin W

Sesamoid bones and accessory ossicles are normal anatomic variants with varying morphological appearances and incidences. They are usually small osseous fragments with well-corticated margins located adjacent to the joint space...
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Nonepisodic angioedema with eosinophilia: A case report of a Korean patient

Choi J, Park SY, Moon KT, Lee WM, Lee BH, Kim SH

Nonepisodic angioedema with eosinophilia (NEAE) is a rare disease characterized by nonrecurrent angioedema with eosinophilia and normal serum IgM levels occurring predominantly in an East Asian female population. A 49-year-old...
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Prognostic Value of Alpha-Fetoprotein in Patients Who Achieve a Complete Response to Transarterial Chemoembolization for Hepatocellular Carcinoma

Lee JS, Chon YE, Kim BK, Park JY, Kim DY, Ahn SH, Han KH, Kang W, Choi MS, Gwak GY, Paik YH, Lee JH, Koh KC, Paik SW, Kim HY, Kim TH, Yoo K, Ha Y, Kim MN, Lee JH, Hwang SG, Kim SS, Cho HJ, Cheong JY, Cho SW, Park SH, Heo NY, Hong YM, Yoon KT, Cho M, Park JG, Kang MK, Park SY, Kweon YO, Tak WY, Jang SY, Sinn DH, Kim SU, The Korean TACE Study Group

Purpose: Alpha-fetoprotein (AFP) is a prognostic marker for hepatocellular carcinoma (HCC). We investigated the prognostic value of AFP levels in patients who achieved complete response (CR) to transarterial chemoembolization (TACE)...
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The Association of Ovarian Reserve with Exposure to Bisphenol A and Phthalate in Reproductive-aged Women

Park SY, Jeon JH, Jeong K, Chung HW, Lee H, Sung YA, Ye S, Ha EH

Background: Exposure to endocrine disrupting chemicals (EDCs) that influence the hormonal and homeostatic systems is known to be associated with gynecologic health risks in many countries. In this study, we...
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Spontaneous Rupture of Uterine Vessels during 3rd Trimester of Pregnancy

Kim TY, Kim YH, Kim JW, Kim AM, Yang YM, Yoon HK, Park SY, Park SJ, Bang HY

A 37-year-old pregnant woman, para 3, was transferred to our hospital at 30 weeks of gestational age with severe acute abdomen. Ultrasonography of the abdomen confirmed that body fluid around...
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Guidelines for Surgery of Confirmed or Suspected COVID-19 Patients

Lee JS, Yum HK, Si HJ, Han SH, Park SY, Peck KR, Eom JS, Korean Society of Infectious Diseases (KSID) and Korea Medical Association Task Force Expert Committee

Coronavirus disease 2019 (COVID-19) has spread widely across the world since January 2020. There are many challenges when caring for patients with COVID-19, one of which is infection prevention and control....
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Repeated Dry Sauna Therapy Improves Quality of Life in Obese Korean People

Choi HS, Kwon H, Cho KH, Thuc LC, Park SY, Kim NH, Kim WJ, Kim YK, Jeon WS, Lee JA, Kim HC, Cho EH

Background: Dry sauna treatments improve the quality of life for chronic pain, congestive heart failure, and type 2 diabetes patients. This study aimed to determine whether dry sauna therapy improved...
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Bone Mineral Density in Diabetes Mellitus Foot Patients for Prediction of Diabetic Neuropathic Osteoarthropathic Fracture

Cho JH, Min TH, Chun DI, Won SH, Park SY, Kim K, Yi Y

Background: Diabetic neuropathic osteoarthropathy (DNOAP) is known as debilitating diabetes complications. The aim of study is to compare bone mineral density (BMD) among diabetic foot and DNOAP, and investigate the...
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Surgical Treatment of Upper Gastrointestinal Tract Crohn Disease: A Long Way to Go to Identify the Optimal Method

Park SY

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