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Association between Hearing Loss and Cognitive Disorder: A Nationwide Population-Based Study

Lee HJ, Joo YH, Han Kd, Park KH

Purpose: To investigate the relationship between hearing loss and cognitive disorder with memory dysfunction in South Korea using data from the Korean Health Insurance claims database for 2009–2015. Materials and Methods:...
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Treatment of Malunion

Kim JW, Park KH, Oh CW

Although current surgical techniques have reduced the incidence of malunion, it is still observed because of the complexity of the fracture or associated injuries. Osteotomy is needed when the amount...
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Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006)

Ahn SG, Nam SJ, Ahn SH, Jung Y, Park HK, Lee SJ, Kang SS, Han W, Park KH, Park YL, Lee J, Youn HJ, Kim JH, Yoo Y, Song JY, Ko BK, Gwak G, Chung MS, Kim SY, Cho SH, Kim D, Chang MC, Moon BI, Kim LS, Kim SJ, Park MH, Kim TH, Cho J, Lim CW, Bae YT, Gong G, Bae YK, Lee A, Jeong J

Purpose: In this trial, we investigated the efficacy and safety of adjuvant letrozole for hormone receptor (HR)-positive breast cancer. Here, we report the clinical outcome in postmenopausal women with HR-positive...
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Etiology, Characteristics, and Outcomes of Community-Onset Pyomyositis in Korea: A Multicenter Study

Kim T, Park SY, Kwak YG, Jung J, Kim MC, Choi SH, Yu SN, Hong HL, Kim YK, Park SY, Song EH, Park KH, Cho OH, Choi SH, TKSSG

Background: Pyomyositis (PM) is a serious soft tissue infection and despite its clinical importance, previous studies have not been able to fully determine the clinical characteristics and microbial epidemiology of...
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Machine-Learning-Based Approach to Differential Diagnosis in Tuberculous and Viral Meningitis

Jeong YS, Jeon M, Park JH, Kim MC, Lee E, Park SY, Lee YM, Choi S, Park SY, Park KH, Kim SH, Jeon MH, Choo EJ, Kim TH, Lee MS, Kim T

Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis, but differentiating between the diagnosis of TBM and viral meningitis (VM) is difficult. Thus, we have developed machine-learning modules...
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Validation of a New Screening Tool for Dementia: The Simple Observation Checklist for Activities of Daily Living

Park J, Choi H, Jang JW, Lim JS, Yang Y, Lee CN, Park KH

Background and Purpose Screening tests for dementia such as the Mini Mental State Examination (MMSE) and the Montreal Cognitive Assessment are widely used, but there are drawbacks to their efficient...
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Comparison of Allergenic Properties among Commercially Available House Dust Mite Allergen Extracts in Korea

Kim JT, Kim H, Kim SH, Kim DJ, Shin Y, Kim JD, Song H, Jang SW, Lee Dc, Park KH, Lee JH, Jeong KY, Park JW

Precise allergy diagnosis and effective allergen specific immunotherapy are largely dependent on the quality of allergen extract. A new extract of Dermatophagoides farinae was commercially developed by Prolagen. The allergenic...
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Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients

Bae H, Na DH, Chang JY, Park KH, Min JW, Ko EJ, Lee H, Yang CW, Chung BH, Oh EJ

Background/Aims To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods We...
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Usefulness of Reference Change Values for Delta Check Limits in Clinical Laboratory Testing

Lee S, Son JO, Kwon H, Park KH, Yu GG, Han E, Jekarl DW, Kim Y

Background: In this study, the usefulness of within-subject biological coefficient of variation (CVI) and reference change values (RCVs) for delta check limits were investigated by comparing the population distributionbased delta...
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Bioequivalence of the pharmacokinetics between tofacitinib aspartate and tofacitinib citrate in healthy subjects

Shin W, Yang AY, Yun H, Cho DY, Park KH, Shin H, Kim A

Tofacitinib is an oral disease-modifying anti-rheumatic drug to selectively inhibit Janus kinases. Tofacitinib is a representative small molecule inhibitor that is used to treat many diseases including rheumatoid arthritis and...
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Negative school experiences of Late Millennial Korean medical students: a qualitative study using the critical incident technique

Roh H, Yune SJ, Park KH, Lee GH, Jung SS, Chun KH

Purpose: Today's students have distinctive generational characteristics and increased psychopathology and generational tension. The authors investigated the negative experiences of Late Millennial students in medical school to draw implications for...
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Viral Load Kinetics of SARS-CoV-2Infection in Saliva in Korean Patients:a Prospective Multi-center Comparative Study

Kim SE, Lee JY, Lee A, Kim S, Park KH, Jung SI, Kang SJ, Oh TH, Kim UJ, Lee SY, Kee SJ, Jang HC

Background: This study was performed to compare the viral load and kinetics of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in saliva with those in standard nasopharyngeal/oropharyngeal (NP/OP) swabs. Methods: Fifteen patients...
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Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020

Sung HK, Kim JY, Heo J, Seo H, Jang Ys, Kim H, Koh BR, Jo N, Oh HS, Baek YM, Park KH, Shon JA, Kim MC, Kim JH, Chang HH, Park Y, Kang YM, Lee DH, Oh DH, Park HJ, Song KH, Lee EK, Jeong H, Lee JY, Ko JY, Choi J, Ryu EH, Chung Kh, Oh Md, The Korea National Committee for Clinical Management of COVID-19

Background: The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity of healthcare systems, and the quality of medical care....
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Effects of Air Purifiers on Patients with Allergic Rhinitis: a Multicenter, Randomized, Double-Blind, and Placebo-Controlled Study

Park KH, Sim DW, Lee SC, Moon S, Choe E, Shin H, Kim SR, Lee JH, Park HH, Huh D, Park JW

Purpose: Exposure to particulate matter (PM) is a well-known risk factor in the triggering and exacerbation of allergic airway disease. Indoor environments, where people spend most of their time, are...
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Two New Species of Laccaria (Agaricales, Basidiomycota) from Korea

Cho HJ, Lee H, Park MS, Park KH, Park JH, Cho Y, Kim C, Lim YW

Species of Laccaria (Hydnangiaceae, Agaricales, and Basidiomycota) are well-known ectomycorrhizal symbionts of a broad range of hosts.Laccaria species are characterized by brown, orange, or purple colored basidiocarps, and globose or...
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The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 1. Definition, Methodology and First-line Management

Song WJ, Choi M, Lee DH, Kwon JW, Kim GW, Kim MH, Kim MA, Kim MH, Kim BK, Kim S, Kim JS, Kim JE, Kim JY, Kim JH, Kim HJ, Kim HO, Kim HB, Roh JY, Park KH, Park KY, Park HK, Park H, Bae JM, Byun JY, Song DJ, Ahn YM, Lee SE, Lee YB, Lee JS, Lee JH, Lim KH, Ye YM, Chang YS, Jeon YH, Jeon J, Jue MS, Choi SH, Choi JH, Hur GY, Park YM, Lim DH, Youn SW

Chronic spontaneous urticaria (CSU) is defined as the occurrence of spontaneous wheals, angioedema, or both for >6 weeks in the absence of specific causes. It is a common condition associated...
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Diagnosis and Operation Results for Chronic Lateral Ankle Instability with Subtle Cavovarus Deformity and a Peek-A-Boo Heel Sign

Shim DW, Suh JW, Park KH, Lee JW, Byun J, Han SH

Cavovarus deformity is considered an anatomical risk factor for chronic lateral ankle instability (CLAI). However, subtle deformity can be difficult to detect, and its correction is controversial. The current study...
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Clinical Implication of Concordant or Discordant Genomic Profiling between Primary and Matched Metastatic Tissues in Patients with Colorectal Cancer

Choi JY, Choi S, Lee M, Park YS, Sung JS, Chang WJ, Kim JW, Choi YJ, Kim J, Kim DS, Lee SH, Seok J, Park KH, Kim SH, Kim YH

Purpose The purpose of this study was to identify the concordant or discordant genomic profiling between primary and matched metastatic tumors in patients with colorectal cancer (CRC) and to explore the...
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Seventeen Unrecorded Species from Gayasan National Park in Korea

Lee H, Park MS, Park JH, Cho HJ, Park KH, Yoo S, Lee JW, Kim NK, Lee JS, Park JY, Kim C, Kim JJ, Lim YW

Macrofungi play important roles in forest ecology as wood decayers, symbionts, and pathogens of living trees. For the effective forest management, it is imperative to have a comprehensive overview of...
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Changes in Neck Angle, Neck Length, Maximum Diameter, Maximum Area and Thrombus after Endovascular Aneurysm Repair

Lee JH, Park KH, Kwak SG

Purpose: The correlation of initial anatomy of the aneurysm, aneurysmal remodeling and endoleaks is controversial. We performed a retrospective study to measure aneurysmal remodeling with time, and to assess the...
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