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Comparative analysis of serological tests and fecal detection in the diagnosis of Mycobacterium avium subspecies paratuberculosis infection

Park HT, Ha S, Park HE, Shim S, Hur TY, Yoo HS

Abstract: Johne's disease (JD) caused by Mycobacterium avium subspecies paratuberculosis (MAP) is a chronic, wasting infectious disease in ruminants that causes enormous economic losses to the dairy and beef cattle...
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Pattern of Extraocular Muscle Involvements in Miller Fisher Syndrome

Ryu WY, Kim YH, Yoon BA, Park HT, Bae JS, Kim JK

BACKGROUND AND PURPOSE: The most-common initial manifestation of Miller Fisher syndrome (MFS) is diplopia due to acute ophthalmoplegia. However, few studies have focused on ocular motility findings in MFS. This...
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miR-381 Attenuates Peripheral Neuropathic Phenotype Caused by Overexpression of PMP22

Lee JS, Kwak G, Kim HJ, Park HT, Choi BO, Hong YB

Charcot-Marie Tooth disease type 1A (CMT1A), the major type of CMT, is caused by duplication of peripheral myelin protein 22 (PMP22) gene whose overexpression causes structural and functional abnormalities in...
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Evaluation of the immunobiological effects of a regenerative far-infrared heating system in pigs

Kim S, Park HT, Soh SH, Oh MW, Shim S, Yoo HS

Thermal conditions are an important environmental factor in maintaining healthy pigs because they affect feed intake, growth efficiency, reproduction and immune responses in pigs. RAVI, a regenerative far-infrared heating system,...
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Clinical evaluation and management of endometriosis: guideline for Korean patients from Korean Society of Endometriosis

Hwang H, Chung YJ, Lee SR, Park HT, Song JY, Kim H, Lee DY, Lee EJ, Kim MR, Oh ST

Endometriosis is one of the most common diseases in reproductive ages, and it affects patients' quality of life and fertility. However, few Korean guidelines are available for the evaluation and...
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Genetic diversity of bovine Mycobacterium avium subsp. paratuberculosis discriminated by IS1311 PCR-REA, MIRU-VNTR, and MLSSR genotyping

Park HT, Park HE, Park WB, Kim S, Hur TY, Jung YH, Yoo HS

The aim of this study was to describe the genetic diversity of Mycobacterium avium subsp. paratuberculosis (MAP) obtained from individual cows in Korea. Twelve MAP-positive fecal DNA samples and 19...
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Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions

Chelakkot , Choi Y, Kim DK, Park HT, Ghim J, Kwon Y, Jeon J, Kim MS, Jee YK, Gho YS, Park HS, Kim YK, Ryu SH

The gut microbiota has an important role in the gut barrier, inflammation and metabolic functions. Studies have identified a close association between the intestinal barrier and metabolic diseases, including obesity...
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Gene Expression Profiles of Th1-type Chemokines in Whole Blood of Mycobacterium avium subsp. paratuberculosis-Infected Cattle

Shin MK, Park HE, Park HT, Jung M, Kang HL, Baik SC, Lee WK, Jung YH, Yoo HS

Johne's disease (JD) is a chronic, debilitating disease of ruminants including cows, and is caused by Mycobacterium avium subsp. paratuberculosis (MAP). MAP is not only important in animal husbandry, but...
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A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution

Heo K, Lim SM, Nahm M, Kim YE, Oh KW, Park HT, Ki CS, Kim SH, Lee S

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is frequently linked to microtubule abnormalities and mitochondrial trafficking defects. Whole exome sequencing (WES) of patient-parent trios has proven to...
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Adipogenic and Lipolytic Effects of Ascorbic Acid in Ovariectomized Rats

Kim B, Choi KM, Yim HS, Park HT, Yim JH, Lee MG

PURPOSE: Ascorbic acid has been reported to have an adipogenic effect on 3T3-L1 preadipocytes, while evidence also suggests that ascorbic acid reduces body weight in humans. In this study, we...
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Potential biomarkers as an indicator of vertical transmission of Johne's disease in a Korean native cattle farm

Park HT, Park HE, Cho YI, Kim EH, Jung M, Shin SW, Lee SH, Kim DY, Yoo HS

Paratuberculosis (PTB) is caused by Mycobacterium avium subsp. paratuberculosis (MAP) and is one of the most widespread and economically important diseases in cattle. After birth, calves are raised with natural...
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Effect of ionizing radiation at low dose on transgenerational carcinogenesis by epigenetic regulation

Li L, Kim JH, Park HT, Lee JH, Park MK, Lee JW, Lee JC, Lee MJ

The objective of this study was to determine the effect of ionizing radiation (IR) exposure of parents on carcinogenesis of the next generation focusing on the epigenetic perspective to clarify...
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The Scaffolding Protein, Grb2-associated Binder-1, in Skeletal Muscles and Terminal Schwann Cells Regulates Postnatal Neuromuscular Synapse Maturation

Park SY, Jang SY, Shin YK, Jung DK, Yoon BA, Kim JK, Jo YR, Lee HJ, Park HT

The vertebrate neuromuscular junction (NMJ) is considered as a “tripartite synapse” consisting of a motor axon terminal, a muscle endplate, and terminal Schwann cells that envelope the motor axon terminal....
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Validity Test of K-SKAGOAO for Korean Nursing Groups and the Relationship of Nursing Group Power and Job Satisfaction, Organizational Commitment, Organizational Performance

Sung YH, Jeong JH, Park HT, Lee MK

PURPOSE: The purpose of this study was to test validity and reliability of the Korean-Sieloff King Assessment of Group Outcome Attainment within organization in Korea (K-SKAGOAO), and also to explore...
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The role of sex steroid hormones in the pathophysiology and treatment of sarcopenia

Kim YJ, Tamadon A, Park HT, Kim H, Ku SY

Sex steroids influence the maintenance and growth of muscles. Decline in androgens, estrogens and progesterone by aging leads to the loss of muscular function and mass, sarcopenia. These steroid hormones...
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Development of vaccines to Mycobacterium avium subsp. paratuberculosis infection

Park HT, Yoo HS

Johne's disease or paratuberculosis is a chronic debilitating disease in ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). The disease causes significant economic losses in livestock industries worldwide. There are...
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Vasomotor symptoms and the homeostatic model assessment of insulin-resistance in Korean postmenopausal women

Kwon DH, Lee JH, Ryu KJ, Park HT, Kim T

The aim of this cross-sectional study was to evaluate the association between vasomotor symptoms (VMS) and insulin resistance, which can be postulated by the homeostatic model assessment (HOMA) index. This...
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Virulence factors, antimicrobial resistance patterns, and genetic characteristics of hydrogen sulfide-producing Escherichia coli isolated from swine

Park HE, Shin MK, Park HT, Shin SW, Jung M, Im YB, Yoo HS

Escherichia (E.) coli is commensal bacteria found in the intestine; however, some pathogenic strains cause diseases in animals and humans. Although E. coli does not typically produce hydrogen sulfide (H2S),...
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Discovery of antigens for early detection of Mycobacterium avium subsp. paratuberculosis and analysis of characteristics using bioinformatics tools

Park HT, Park HE, Shin MK, Cho YI, Yoo HS

Johne's disease, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is one of the most widespread and economically important diseases in cattle. Current diagnostic methods are based on the detection of...
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Mitogen Activated Protein Kinase Family Proteins and c-jun Signaling in Injury-induced Schwann Cell Plasticity

Lee HJ, Shin YK, Park HT

Schwann cells (SCs) in the peripheral nerves myelinate axons during postnatal development to allow saltatory conduction of nerve impulses. Well-organized structures of myelin sheathes are maintained throughout life unless nerves...
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