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PTEN Promoter Hypermethylation Is Associated with Breslow Thickness in Acral Melanoma on the Heel, Forefoot, and Hallux

Park HS, Kim JH, Cho MY, Chung KY, Roh MR

Background: Acral melanoma occurs on glabrous skin or the nail apparatus and is distinct from ultraviolet-related melanoma due to differing genetic alteration patterns. Although the pathogenesis of acral melanoma is...
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Impact of Cardiovascular Risk Factors and Cardiovascular Diseases on Outcomes in Patients Hospitalized with COVID-19 in Daegu Metropolitan City

Park BE, Lee JH, Park HK, Kim HN, Jang SY, Bae MH, Yang DH, Park HS, Cho Y, Lee BY, Nam CW, Lee JB, Kim U, Chae SC, the Daegu COVID-19 Research Project

Background: Data regarding the association between preexisting cardiovascular risk factors (CVRFs) and cardiovascular diseases (CVDs) and the outcomes of patients requiring hospitalization for coronavirus disease 2019 (COVID-19) are limited. Therefore,...
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Clinical outcomes of the first 300 cases of kidney transplantation: a single-center retrospective cohort study

Koh HW, Koo K, Shin CS, Park HS, Jeong JC, Kim S, Chae DW, Oh JJ, Byun SS, Lee T

Background: Kidney transplantation (KT) is regarded as the most effective treatment for end-stage renal disease. The annual number of KT cases in South Korea has increased rapidly as more centers...
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Organizing an in-class hackathon to correct PDF-to-text conversion errors of Genomics & Informatics 1.0

Kim S, Kim R, Kim RG, Ko E, Kim HS, Shin J, Cho D, Jin Y, Bae S, Jo YW, Jeong SA, Kim Y, Ahn S, Jang B, Seong J, Lee Y, Seo SE, Kim Y, Kim HJ, Kim H, Sung HL, Lho H, Koo J, Chu J, Lim J, Kim Y, Lee K, Lim Y, Kim M, Hwang S, Han S, Bae S, Kim S, Yoo S, Seo Y, Shin Y, Kim Y, Ko YJ, Baek J, Hyun H, Choi H, Oh JH, Kim DY, Nam HJ, Park HS

This paper describes a community effort to improve earlier versions of the full-text corpus of Genomics & Informatics by semi-automatically detecting and correcting PDF-to-text conversion errors and optical character recognition...
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Reconstruction of Elbow Joint and Soft Tissue Defect with Anterolateral Thigh Flap and Total Elbow Replacement: A Case Report

Park HS, Kim DJ, Hwang JI

Soft tissue and bone defect due to the machinery penetrating injury of elbow joint are a rare and challenging problem for reconstructive surgeons. After reconstructing soft tissue with anterolateral thigh...
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vidence-Based Nursing Practice Guideline: Ostomy Care

Lee YJ, Park HS, Kim MK, Seo HW, Lee MJ, Won EA, Jo GN

Purpose: The aim of this study was to develop an evidence-based guideline for stoma management providing institutional policy, assessment, complications and follow-up care. Methods: The guideline adaptation manual consisting of...
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Updates of Nursing Practice Guideline for Oral Care

Cho YA, Lee SH, Kim KS, Im HM, Kim TH, Choi MY, Seo HJ, Park HS, Wang KH, Kim CH, Choi HK

Purpose: This study aimed to update the previously published nursing practice guideline for oral care. Methods:The guideline were updated according to the manuals developed by National Institute for Health and...
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Effect of administration of synbiotics mixture containing Bifidobacterium longum and xylooligosaccharide on fecal microbiota and defecation characteristics in healthy volunteers

Lee JS, Park HS, Kyung M, Jo SE, Chang MJ

Purpose: The effect of prebiotics intake after administration of a synbiotics mixture (a probiotic, Bifidobacterium longum, and a prebiotic, xylooligosaccharide containing sugar [XOS]) on human intestinal microflora and defecation characteristics...
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Current treatment strategies for Philadelphia chromosome-positive adult acute lymphoblastic leukemia

Park HS

Acute lymphoblastic leukemia (ALL) is an aggressive hematological disease. The incorporation of tyrosine kinase inhibitors (TKIs) into the standard treatment regimen for Philadelphia (Ph)-positive ALL significantly improved clinical outcomes. TKI-based...
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Activation of Transient Receptor Potential Melastatin Family Member 8 (TRPM8) Receptors Induces Proinflammatory Cytokine Expressions in Bronchial Epithelial Cells

Kim JH, Jang YS, Kim HI, Park JY, Park Sh, Hwang YI, Jang SH, Jung KS, Park HS, Park CS

Purpose: Cold air is a major environmental factor that exacerbates asthma. Transient receptor potential melastatin family member 8 (TRPM8) is a cold-sensing channel expressed in the airway epithelium. However, its...
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Health-Related Utility of EQ-5D in Korean Adults With Chronic Urticaria: Mapping From Urticaria Outcome Measures

Lee MS, Yoon J, Kim J, Shin YS, Park HS, Lee HY, Ye YM

Purpose: A need for useful measures reflective of the socio-economic burden of chronic urticaria (CU) has arisen. To obtain utility estimates for CU, we investigated EuroQol-5-Dimension (EQ-5D) indices according to...
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Is TLR4 Critical for Neutrophil Apoptosis in Occupational Asthma?

Choi Y, Sim S, Park HS

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Clinical Outcome after Treatment of Tibia Segmental Fracture with Intramedullary Nailing and Minimal Invasive Plate Osteosynthesis

Lee JY, Park HS, Cha DH

Purpose: This study examined the clinical outcomes after the treatment of a tibia segmental fracture with intramedullary nailing (IM nailing) and minimal invasive plate osteosynthesis (MIPO). Materials and Methods: From July...
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Impact of Cataract Surgery on Foveal Avascular Zone Detected by Optical Coherence Tomography Angiography

Park HS, Yang JY

Purpose: To investigate the influence of cataract surgery on detection of a foveal avascular zone (FAZ) and retinal capillary density (RCD) by optical coherence tomography angiography (OCTA). Methods: In this study,...
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A Case of COVID-19 with Acute Myocardial Infarction and Cardiogenic Shock

Kim HN, Lee JH, Park HS, Yang DH, Jang SY, Bae MH, Cho Y, Chae SC, Lee YH

A 60-year-old male patient with coronavirus disease-2019 showed new onset ST-segment elevation in V1–V2 leads on electrocardiogram and cardiac enzyme elevation in intensive care unit. He had a history of...
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Camouflage treatment of posterior bite collapse in a patient with skeletal asymmetry by using posterior maxillary segmental osteotomy

Badr H, Lee SY, Park HS, Ohe JY, Kang YG, Ahn HW

Orthodontic treatment of posterior bite collapse due to early loss of molars and the consequent drift of adjacent teeth is complicated. When the posterior bite collapse occurs in patients with...
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Distinct functions of eosinophils in severe asthma with type 2 phenotype: clinical implications

Choi Y, Sim S, Park HS

Asthma is commonly recognized as a heterogeneous condition with a complex pathophysiology. With advances in the development of multiple medications for patients with asthma, most asthma symptoms are well managed....
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Clinicopathological Features of Patients with the BRCA1 c.5339T>C (p.Leu1780Pro) Variant

Park HS, Ryu JM, Park JS, Im SA, Jung SY, Kim EK, Park WC, Min JW, Lee J, You JY, Lee JE, Kim SW

Purpose Recent studies revealed the BRCA1 c.5339T>C, p.Leu1780Pro variant (L1780P) is highly suggested as a likely pathogenic. The aim of this study was to evaluate clinicopathologic features of L1780P with breast...
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Serum potential biomarkers according to sputum inflammatory cell profiles in adult asthmatics

Hur GY, Ye YM, Yang E, Park HS

Background/Aims: Asthma is not a single disease but, rather, a heterogeneous inf lammatory disorder with various pathogenic mechanisms. We analyzed the associations between the cellular profile of sputum and the...
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Effects of Exogenous N-Acyl-Homoserine Lactones on Biofilm Formation and Motility in Acinetobacter nosocomialis

Surendran S, Subhadra B, Woo K, Park HS, Kim DH, Oh MH, Choi CH

One of the major factors contributing to drug resistance in Acinetobacter nosocomialis infections is biofilm development, which is facilitate by quorum-sensing (QS) systems. Quorum sensing by the LuxI and LuxR...
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