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IDH2 gene deficiency accelerates unilateral ureteral obstructioninduced kidney inflammation through oxidative stress and activation of macrophages

Kim JI, Noh MR, Yoon GE, Jang HS, Kong MJ, Park KM

Mitochondrial NADP+-dependent isocitrate dehydrogenase 2 (IDH2) produces NADPH, which is known to inhibit mitochondrial oxidative stress. Ureteral obstruction induces kidney inflammation and fibrosis via oxidative stress. Here, we investigated the...
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Invasive Cutaneous Squamous Cell Carcinoma Arising from Chronic Hidradenitis Suppurativa: A Case Report of Treatment by Slow Mohs Micrographic Surgery

Lee SJ, Lim JM, Lee SH, Chung KY, Roh MR

Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory condition presenting with painful, deep-seated abscesses and sinus tracts in multifocal locations. Rarely, longstanding inflammation in HS may lead to serious complications,...
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PTEN Promoter Hypermethylation Is Associated with Breslow Thickness in Acral Melanoma on the Heel, Forefoot, and Hallux

Park HS, Kim JH, Cho MY, Chung KY, Roh MR

Background: Acral melanoma occurs on glabrous skin or the nail apparatus and is distinct from ultraviolet-related melanoma due to differing genetic alteration patterns. Although the pathogenesis of acral melanoma is...
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A Case of Cutaneous Rosai-Dorfman Disease on the Face Well Improved with Low-dose Systemic Corticosteroid

Lee SG, Yoo DS, Cho MY, Roh MR

  • KMID: 2504352
  • Korean J Dermatol.
  • 2020 Jul;58(6):428-430.
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Clinical Outcomes of Immune Checkpoint Blocker Therapy for Malignant Melanoma in Korean Patients: Potential Clinical Implications for a Combination Strategy Involving Radiotherapy

Lee J, Chang JS, Roh MR, Jung M, Lee CK, Oh BH, Chung KY, Koom WS, Shin SJ

Purpose We investigated the clinical efficacy of immune checkpoint blocker (ICB) therapy for metastatic or advanced melanoma in Korean patients. As well, we assessed whether the effects of ICBs can be...
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Clinicopathological Findings of Pityriasis Lichenoides et Varioliformis Acuta: A Tertiary Hospital Study

Yoo DS, Roh MR

  • KMID: 2503021
  • Korean J Dermatol.
  • 2020 Jun;58(5):305-311.
Background: Pityriasis lichenoides et varioliformis acuta (PLEVA), a type of pityriasis lichenoides disease, is an uncommon inflammatory cutaneous disorder of unknown etiology. PLEVA presents as acute inflammatory papules that progressively...
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Comparison of Usage Patterns and Outcomes by Dual Type Calcium Channel Blockers in Patients with Chronic Kidney Disease

Oh MR, Ahn HL, Choi S, La HO

Background: Dual-type calcium channel blockers (CCBs), such as efonidipine and cilnidipine, are renoprotective drugs that reportedly reduce proteinuria by dilating afferent and efferent arterioles of the glomerulus. However, studies comparing...
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A Histopathologically Rare Case of Adenoid Basal Cell Carcinoma on the Scalp

Yoo DS, Lee YB, Roh MR

  • KMID: 2501912
  • Korean J Dermatol.
  • 2020 Jan;58(1):63-64.
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Basal Cell Carcinoma with Metaplastic Bone Formation

Yoo DS, Park SH, Roh MR

No abstract available.
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Effects of Cordyceps militaris supplementation on the immune response and upper respiratory infection in healthy adults: a randomized, double-blind, placebo-controlled study

Jung SJ, Hwang JH, Oh MR, Chae SW

PURPOSE: Upper respiratory tract infections are major causes of the common cold throughout the world. Cordyceps militaris (C. militaris) is a well-known functional food for its anti-fatigue and immunomodulating activities....
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Clinical Features and Association with Visceral Malignancy in 80 Patients with Sebaceous Neoplasms

Kim JE, Kim JH, Chung KY, Yoon JS, Roh MR

BACKGROUND: Sebaceous neoplasm is a rare subgroup of appendageal tumors that differentiate towards sebaceous adnexal structures of the skin and are known to be associated with visceral malignancy. OBJECTIVE: We aimed...
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Multiple Trichoepitheliomas Identified in a Patient with Neurofibromatosis Type 1

Cho MY, Park SH, Roh MR

No abstract available.
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Extraneural CGRP Induces Oxidative Stress in Kidney Proximal Tubule Epithelial Cells

Moon D, Yoon SP, Jang HS, Noh MR, Ha L, Padanilam , Kim J

Calcitonin gene-related peptide (CGRP) is the most abundant neuropeptide in primary afferent sensory neurons. Exogenous CGRP can induce cell death in kidney tubular cells. The objective of this study was...
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Immediate Umbilical Reconstruction after a Mohs Micrographic Surgery for Primary Cutaneous Adenoid Cystic Carcinoma Arising in the Umbilicus

Kim JE, Roh MR, Chung KY

Adenoid cystic carcinoma (ACC) is a malignant neoplasm of glands commonly occurs in salivary glands. Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare form of ACC that primarily presents...
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A Case of Canalicular Adenoma Arising on the Upper Lip

Seo SH, Kim JH, Cha H, Roh MR

Canalicular adenoma is a rare benign tumor that arises in the minor salivary gland. Clinically, it usually presents as an asymptomatic nodule on the upper lip or buccal mucosa. It...
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A Case of Eosinophilic Annular Erythema

Kim JE, Roh MR

Eosinophilic annular erythema (EAE) is a rare, recurrent disease of unknown etiology with tissue eosinophilia that was initially reported in a pediatric patient. It is debatable whether EAE is a...
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A Case of Giant Basal Cell Carcinoma Healed with Secondary Closure through Purse String Suture after Mohs Micrographic Surgery

Park HS, Kim JH, Roh MR

No abstract available.
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Genetic Alterations among Korean Melanoma Patients Showing Tumor Heterogeneity: A Comparison between Primary Tumors and Corresponding Metastatic Lesions

Lee SH, Kim JE, Jang HS, Park KH, Oh BH, Shin SJ, Chung KY, Roh MR, Rha SY

PURPOSE: Melanoma is a highly heterogeneous neoplasm, composed of subpopulations of tumor cells with distinct molecular and biological phenotypes and genotypes. In this study, to determine the genetic heterogeneity between...
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Centennial History of Yonsei University Dermatology in Korea: 1917 to 2017

Kim J, Kim TG, Lee SH, Lee MK, Kim JH, Lee SE, Kim DY, Roh MR, Park CO, Lee JH, Lee MG, Bang D, Oh SH, Chung KY

Yonsei Dermatology celebrated its centennial in 2017, marking 100 years since Kung Sun Oh established the first Department of Dermatology and Urology in Korea in 1917. Following the footsteps of...
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Scar Sarcoidosis after Blepharoplasty: A Case Series

Choi JY, Lee JH, Kim TH, Kim SC, Roh MR

Scar sarcoidosis is a cutaneous manifestation of sarcoidosis arising on old cutaneous scars. We report four cases of scar sarcoidosis after blepharoplasty. Lesions were seen to manifest as erythematous, firm,...
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