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Severe Late-onset Anemia Associated with Rhesus D Alloimmunization

Jeon J, Lim G, Oh KW

Rhesus D (RhD) alloimmunization is the most severe cause of hemolytic disease of the fetus and newborn (HDFN). However, owing to medical advances, pediatricians are likely to encounter only a...
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Post-Traumatic Guillain-Barre Syndrome

Jo SH, Lee J, Lee J, Kim JH, Park J, Kim SH, Oh Kw

Guillain-Barre syndrome (GBS) is acute inflammatory demyelinating polyradiculoneuropathy, which is often related to post-infectious etiology. However, GBS has also been reported to be caused by non-infectious factors such as trauma....
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Hepatic Subcapsular Hematoma with Different Clinical Features in Two Neonates

Oh Y, Lim G, Oh KW

The liver of a newborn is vulnerable to damage during the process of delivery or on external manipu lation. Although hepatic subcapsular hematoma occurs relatively commonly in the perinatal period,...
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A Therapeutic Strategy for Alzheimer's Disease Focused on Immune-inflammatory Modulation

Kim SH, Noh MY, Kim HJ, Oh KW, Park J, Lee S, Moon Y, Kim YE, Bae JS, Jin HK, K-ARPI

Alzheimer's disease (AD), the most common form of dementia, has emerged as a major global public health challenge. However, the complexity of AD in its biological, genetic, and clinical aspects...
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A prospective clinical of lithium disilicate pressed zirconia and monolithic zirconia in posterior implant-supported prostheses: A 24-month follow-up

Roh KW, Jeon YC, Jeong CM, Yun MJ, Huh JB, Lee SH, Yang DS, Bae EB

PURPOSE: The purpose of this study was to compare the clinical outcomes of lithium disilicate ceramic pressed zirconia prostheses and monolithic zirconia prostheses and to investigate the complications after two...
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Clinical Evaluation of Lithium Disilicate Pressed Zirconia and Monolithic Zirconia in Posterior Implant-Supported Prostheses

Roh KW, Yang DS, Jeon YC, Jeong CM, Yun MJ, Lee SH, Choi JW, Lee JJ, Bae EB, Huh JB

PURPOSE: The purpose of this study was to compare the clinical outcomes of lithium disilicate pressed zirconia prostheses and monolithic zirconia prostheses, which are widely used as posterior implant restorations,...
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Deficiency of Sphingosine-1-Phosphate Reduces the Expression of Prohibitin and Causes β-Cell Impairment via Mitochondrial Dysregulation

Hong SW, Lee J, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: Emerging evidence suggests that sphingolipids may be involved in type 2 diabetes. However, the exact signaling defect through which disordered sphingolipid metabolism induces β-cell dysfunction remains unknown. The current...
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Cocaine- and Amphetamine-Regulated Transcript (CART) Peptide Plays Critical Role in Psychostimulant-Induced Depression

Meng Q, Kim HC, Oh S, Lee YM, Hu Z, Oh KW

Cocaine- and amphetamine-regulated transcript (CART) peptide is a widely distributed neurotransmitter expressed in the central nervous systems. Previously, several reports demonstrated that nucleus accumbal-injected CART peptide positively modulated behavioral sensitization...
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Subacute Combined Degeneration and Pulmonary Thromboembolism due to Nitrous Oxide Inhalation for Recreational Use

Kim SJ, Lee J, Kim YS, Oh KW, Kim SH, Park J

No abstract available.
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Sleep-Aids Derived from Natural Products

Hu Z, Oh S, Ha TW, Hong JT, Oh KW

Although drugs such as barbiturates and benzodiazepines are often used for the treatment of insomnia, they are associated with various side effects such as habituations, tolerance and addiction. Alternatively, natural...
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Administration of Alpha(s1)-Casein Hydrolysate Increases Sleep and Modulates GABA(A) Receptor Subunit Expression

Yayeh T, Leem YH, Kim KM, Jung JC, Schwarz J, Oh KW, Oh S

Sleep is the most basic and essential physiological requirement for mental health, and sleep disorders pose potential risks of metabolic and neurodegenerative diseases. Tryptic hydrolysate of α(S1)-casein (α(S1)-CH) has been...
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Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition

Chung YH, Oh KW, Kim ST, Park ES, Je HD, Yoon HJ, Sohn UD, Jeong JH, La HO

The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine the mechanism underlying the relaxation. Denuded aortic rings from male...
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Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Hong SW, Lee J, Cho JH, Kwon H, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: The nuclear receptor peroxisome proliferator-activator gamma (PPARγ) is a useful therapeutic target for obesity and diabetes, but its role in protecting β-cell function and viability is unclear. METHODS: To identify...
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The Association between Persistent Hypertriglyceridemia and the Risk of Diabetes Development: The Kangbuk Samsung Health Study

Kwon YH, Kim SK, Cho JH, Kwon H, Park SE, Oh HG, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ

BACKGROUND: Hypertriglyceridemia is known to have an association with increased risks of insulin resistance and diabetes. The aim of this study was to investigate the risk of diabetes mellitus, according...
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Data resource profile: oral examination of the Korea National Health and Nutrition Examination Survey

Woo GJ, Lee HR, Kim Y, Kim HJ, Park DY, Kim JB, Oh KW, Choi YH

OBJECTIVES: The Korea National Health and Nutrition Examination Survey (KNHANES) is a national surveillance system that has been assessing the health and nutritional status of Koreans since 1998. Based on...
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A De Novo RAPGEF2 Variant Identified in a Sporadic Amyotrophic Lateral Sclerosis Patient Impairs Microtubule Stability and Axonal Mitochondria Distribution

Heo K, Lim SM, Nahm M, Kim YE, Oh KW, Park HT, Ki CS, Kim SH, Lee S

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is frequently linked to microtubule abnormalities and mitochondrial trafficking defects. Whole exome sequencing (WES) of patient-parent trios has proven to...
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Implant assisted removable partial denture with implant surveyed crown: A 20-month follow-up case report

Roh KW, Jeon YC, Jeong CM, Yoon MJ, Lee SH, Huh JB

Traditional options for posterior edentulous treatment include removable partial dentures and implant fixed prostheses. Recently, the concept of implant assisted removable partial denture, in which two treatments are fused, has...
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Inhibitory Effect of Carnosol on Phthalic Anhydride-Induced Atopic Dermatitis via Inhibition of STAT3

Lee DY, Hwang CJ, Choi JY, Park MH, Song MJ, Oh KW, Son DJ, Lee SH, Han SB, Hong JT

Carnosol is a phenolic antioxidant present in rosemary (Rosmarinus officinalis). It is known for anti-inflammatory effects, analgesic activity and anti-cancer effects. However, no study has been dedicated yet to its...
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Korean Society for Bone and Mineral Research Task Force Report: Perspectives on Intermittent High-dose Vitamin D Supplementation

Choi HS, Min YK, Byun DW, Hahn MH, Kim KM, Kim BJ, Oh KW

An adequate supply of vitamin D is considered necessary for osteoporosis management and fracture prevention. Intermittent high-dose vitamin D supplementation is an effective and convenient way to achieve and maintain...
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Changes in skin reactivity and associated factors in patients sensitized to house dust mites after 1 year of allergen-specific immunotherapy

Son JY, Jung MH, Koh KW, Park EK, Heo JH, Choi GS, Kim HK

BACKGROUND: Allergen-specific immunotherapy (SIT) can significantly improve symptoms and reduce the need for symptomatic medication. OBJECTIVE: The aim of this study was to investigate changes in skin reactivity to house dust...
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