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Relationship between Nonalcoholic Fatty Liver Disease and High Sensitivity C-Reactive Protein in Healthy Adults

Choi Y, Oh JE, Lee J, Shin HS, Cho YJ, Kim SH, Joe H, Yoo BW, Hong SH, Cho CY, Son DY, Shin KS

Background: Recent studies have shown that nonalcoholic fatty liver disease (NAFLD) is associated with higher levels of high sensitivity C-reactive protein (hs-CRP), a predictor of increased risk of developing cardiovascular...
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Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection

Kim CW, Oh JE, Lee HK

The coronavirus disease 2019 (COVID-19) pandemic (severe acute respiratory syndrome coronavirus 2) is a global infectious disease with rapid spread. Some patients have severe symptoms and clinical signs caused by...
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Intracerebral Transplantation of BDNF-overexpressing Human Neural Stem Cells (HB1.F3.BDNF) Promotes Migration, Differentiation and Functional Recovery in a Rodent Model of Huntington’s Disease

Kim HS, Jeon I, Noh JE, Lee H, Hong KS, Lee N, Pei Z, Song J

  • KMID: 2500524
  • Exp Neurobiol.
  • 2020 Apr;29(2):130-137.
  • doi: 10.5607/en20011
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by abnormally expanded CAG repeats in the huntingtin gene. The huntingtin gene mutation leads to the progressive degeneration of striatal...
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The Change of Metabolic Syndrome Prevalence and Its Risk Factors in Korean Adults for Decade: Korea National Health and Nutrition Examination Survey for 2008–2017

Kim Mh, Lee Sh, Shin KS, Son DY, Kim SH, Joe H, Yoo BW, Hong SH, Cho CY, Shin HS, Cho YJ, Oh JE

Background: Metabolic syndrome is a nationwide health problem, which is associated with the development of cardiovascular diseases, diabetes, and chronic renal failure. The prevalence of metabolic syndrome in Korea significantly...
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The Relation of High-Sensitivity C-Reactive Protein with Hyperuricemia: Using Health Examination Data at One Medical Institution’s Health Examination Center (2016–2017)

Kim Db, Oh JE, Park Hs, Shin HS, Cho YJ, Kim Sh, Joe H, Yoo BW, Hong SH, Cho CY, Son DY, Shin KS

Background: Several studies have shown that elevated serum uric acid levels are associated with cardiovascular disease. High sensitivity C-reactive protein (hs-CRP) has been shown to be a measure of the...
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Clinical Guidance for Point-of-Care Ultrasound in the Emergency and Critical Care Areas after Implementing Insurance Coverage in Korea

Choi WJ, Ha YR, Oh JH, Cho YS, Lee WW, Sohn YD, Cho GC, Koh CY, Do HH, Jeong WJ, Ryoo SM, Kwon JH, Kim HM, Kim SJ, Park CY, Lee JH, Lee JH, Lee DH, Park SY, Kang BS

Point-of-care ultrasound (POCUS) is a useful tool that is widely used in the emergency and intensive care areas. In Korea, insurance coverage of ultrasound examination has been gradually expanding in...
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Magnetic Resonance-Based Texture Analysis Differentiating KRAS Mutation Status in Rectal Cancer

Oh JE, Kim MJ, Lee J, Hur BY, Kim B, Kim DY, Baek JY, Chang HJ, Park SC, Oh JH, Cho SA, Sohn DK

Purpose Mutation of the Kirsten Ras (KRAS) oncogene is present in 30%-40% of colorectal cancers and has prognostic significance in rectal cancer. In this study, we examined the ability of radiomics...
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A Rare Case of Syphilitic Myelitis of the Spinal Cord

Kim JH, Jeong HS, Park C, Ryu H, Roh JE, Yeom JA, Kim TU

Neurosyphilis is an infection of the brain or spinal cord that is caused by the bacterium Treponema pallidum. Syphilitic myelitis, which involves the spinal cord, is a very rare form...
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Impact of sarcopenia on long-term mortality and cardiovascular events in patients undergoing hemodialysis

Kim JK, Kim SG, Oh JE, Lee YK, Noh JW, Kim HJ, Song YR

BACKGROUND/AIMS: A high body mass index (BMI) is known to correlate with better survival in patients on hemodialysis (HD). However, the impacts of body composition and sarcopenia on survival have...
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The autophagy Protein Atg5 Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells

Jung HE, Shim YR, Oh JE, Oh DS, Lee HK

Hematopoietic stem cells (HSCs) in bone marrow are pluripotent cells that can constitute the hematopoiesis system through self-renewal and differentiation into immune cells and red blood cells. To ensure a...
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Synthesized Ceramide Induces Growth of Dermal Papilla Cells with Potential Contribution to Hair Growth

Oh JH, Jeong KH, Kim JE, Kang H

BACKGROUND: The ceramide is known to play an important role in the formation of intracellular lipids, and play a crucial role as a barrier for skin and hair cuticle. Recent...
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Variations in chest compression time, ventilation time and rescuers' heart rate during conventional cardiopulmonary resuscitation in trained male rescuers

Hong JY, Oh JH

OBJECTIVE: This study was conducted to determine why rescuers could maintain adequate chest compression depth for longer periods during conventional cardiopulmonary resuscitation (CPR). METHODS: Various CPR parameters, including average compression depth...
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Qualitative Comparison of Semantic Memory Impairment in Patients with Amnestic Mild Cognitive Impairment Based on β-Amyloid Status

Kim JE, Park SH, Hong YJ, Hwang J, Han NE, Lee SM, Roh JH, Kim JS, Lee JH

BACKGROUND AND PURPOSE: Semantic memory remains more stable than episodic memory across the lifespan, which makes it potentially useful as a marker for distinguishing pathological aging from normal senescence. To...
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Increased procalcitonin level is a risk factor for prolonged fever in children with Mycoplasma pneumonia

Jeong JE, Soh JE, Kwak JH, Jung HL, Shim JW, Kim DS, Park MS, Shim JY

PURPOSE: Macrolide-resistant Mycoplasma pneumoniae pneumonia (MPP) is characterized by prolonged fever and radiological progression despite macrolide treatment. Few studies have examined serum procalcitonin (PCT) level in children with MPP. We...
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Clinical and molecular characteristics of pulmonary sarcomatoid carcinoma

Sim JK, Chung SM, Choi JH, Oh JY, Lee SH, Kim JH, Min KH, Hur GY, Shim JJ, Kang KH, Shin BK, Lee JH, Lee SY

BACKGROUND/AIMS: Pulmonary sarcomatoid carcinoma (PSC) is a poorly differentiated non-small cell lung cancer (NSCLC) that contains components of spindle or giant cells. Owing to its low prevalence, there are insufficient...
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Comparing Two Mycobacterium tuberculosis Genomes from Chinese Immigrants with Native Genomes Using Mauve Alignments

Ryoo S, Lee J, Oh JY, Kim BK, Kim Y, Kim JH, Shin C, Lee SH

BACKGROUND: The number of immigrants with tuberculosis (TB) increases each year in South Korea. Determining the transmission dynamics based on whole genome sequencing (WGS) to cluster the strains has been...
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Relationship between heavy drinking, binge drinking, and metabolic syndrome in obese and non-obese Korean male adults

Oh JE

BACKGROUND/OBJECTIVES: Obesity and alcohol drinking are associated with metabolic syndrome. However, few studies show the relationship between alcohol drinking and metabolic syndrome according to varying degrees of obesity. This study...
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The factors associated with Vitamin D deficiency in community dwelling elderly in Korea

Kim SH, Oh JE, Song DW, Cho CY, Hong SH, Cho YJ, Yoo BW, Shin KS, Joe H, Shin HS, Son DY

BACKGROUND/OBJECTIVES: Recent studies showed vitamin D deficiency is linked to chronic diseases in addition to skeletal metabolism which could threaten the elderly. We analyzed health conditions and socio-demographic factors associated...
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Relationship of serum vitamin D and interleukin-31 levels to allergic or nonallergic rhinitis in children

Park SJ, Soh JE, Park MS, Jung HL, Shim JW, Kim DS, Shim JY

PURPOSE: Serum vitamin D (25-hydroxyvitamin D, 25[OH] D) and interleukin-31 (IL-31) are related to atopic dermatitis, but their relationship with allergic rhinitis is unclear. The purpose of this study was...
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Remote Ischemic Conditioning by Effluent Collected from a Novel Isolated Hindlimb Model Reduces Infarct Size in an Isolated Heart Model

Youn YJ, Yoo BS, Son JW, Lee JW, Ahn MS, Ahn SG, Kim JY, Lee SH, Yoon J, Eom YW, Oh JE, Choi SK

BACKGROUND AND OBJECTIVES: Experimental protocols for remote ischemic conditioning (RIC) utilize models in which a tourniquet is placed around the hindlimb or effluent is collected from an isolated heart. In...
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