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Higher thoracic radiation dose is beneficial in patients with extensive small cell lung cancer

Yoon HG, Noh JM, Ahn YC, Oh D, Pyo H, Kim H

PURPOSE: The effectiveness of thoracic radiation therapy (TRT) in extensive-stage small cell lung cancer (ES-SCLC) patients is increasingly reported, but there is no definite consensus on its application. The aim...
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Dummy Run of Quality Assurance Program before Prospective Study of Hippocampus-Sparing Whole-Brain Radiotherapy and Simultaneous Integrated Boost for Multiple Brain Metastases from Non-small Cell Lung Cancer: Korean Radiation Oncology Group (KROG) 17-06 Study

Chung E, Noh JM, Lee KC, Kim JH, Chung WK, Suh YG, Lee JA, Seol KH, Wu HG, Kim YS, Noh OK, Park JW, Lee DS, Lee J, Kim YS, Park WY, Kang MK, Jo S, Ahn YC

PURPOSE: Lung Cancer Subcommittee of Korean Radiation Oncology Group (KROG) has recently launched a prospective clinical trial (KROG 17-06) of hippocampus-sparing whole brain radiotherapy (HS-WBRT) with simultaneous integrated boost (SIB)...
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Salvage Concurrent Chemo-radiation Therapy for Loco-regional Recurrence Following Curative Surgery of Non-small Cell Lung Cancer

Lee KH, Ahn YC, Pyo H, Noh JM, Park SG, Kim TG, Lee E, Nam H, Lee H, Sun JM, Ahn JS, Ahn MJ, Park K

PURPOSE: This study is to report clinical outcomes of salvage concurrent chemo-radiation therapy (CCRT) in treating patients with loco-regional recurrence (LRR) following initial complete resection of non-small cell lung cancer. MATERIALS...
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Feasibility of Selective Neck Irradiation with Lower Elective Radiation Dose in Treating Nasopharynx Cancer Patients

Cho WK, Oh D, Lee E, Kim TG, Lee H, Nam H, Noh JM, Ahn YC

PURPOSE: This study aimed to report the clinical outcomes following selective neck irradiation (SNI) with lower elective radiation therapy (RT) dose in treating nasopharyngeal cancer (NPC) patients. MATERIALS AND METHODS: A...
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EGFR Mutation Is Associated with Short Progression-Free Survival in Patients with Stage III Non-squamous Cell Lung Cancer Treated with Concurrent Chemoradiotherapy

Park SE, Noh JM, Kim YJ, Lee HS, Cho JH, Lim SW, Ahn YC, Pyo H, Choi YL, Han J, Sun JM, Lee SH, Ahn JS, Park K, Ahn MJ

PURPOSE: This study was conducted to evaluate the relationship between epidermal growth factor receptor (EGFR) mutation and clinical outcomes in patients with stage III non-squamous cell lung cancer treated with...
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Complex regional pain syndrome in the young male population: a retrospective study of 200 Korean young male patients

Lee HJ, Lee CS, Yoo Y, Noh JM, Yu JH, Kim YC, Moon JY

BACKGROUND: The aim of this study was to investigate the clinical characteristics of complex regional pain syndrome (CRPS) in young male patients in South Korea, especially focusing on the association...
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The Effect of Hospital Case Volume on Clinical Outcomes in Patients with Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Analysis (KROG-1106)

Ha B, Cho KH, Moon SH, Lee CG, Keum KC, Kim YS, Wu HG, Kim JH, Ahn YC, Oh D, Noh JM, Lee JH, Kim SH, Kim WT, Oh YT, Kang MK, Kim JH, Kim JY, Cho MJ, Kay CS, Choi JH

PURPOSE: The purpose of this study was to investigate the effect of hospital case volume on clinical outcomes in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: Data on 1,073 patients...
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Role of Adjuvant Thoracic Radiation Therapy and Full Dose Chemotherapy in pN2 Non-small Cell Lung Cancer: Elucidation Based on Single Institute Experience

Park H, Oh D, Ahn YC, Pyo H, Noh JM, Sun JM, Ahn JS, Ahn MJ, Park K, Kim HK, Choi YS, Kim J, Zo JI, Shim YM

PURPOSE: The optimal adjuvant therapy modality for treating pN2 non-small cell lung cancer patients has not yet been established. In this study, the authors investigated clinical outcomes following three different...
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Immunomodulatory effect of captopril and local irradiation on myeloid-derived suppressor cells

Cho WK, Shin SW, Kim SY, Hong CW, Choi C, Park W, Noh JM

PURPOSE: This study is to investigate the effect of captopril when combined with irradiation. MATERIALS AND METHODS: 4T1 (mouse mammary carcinoma) cells were injected in the right hind leg of Balb/c...
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The Role of Neoadjuvant Chemotherapy in the Treatment of Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Study (KROG 11-06) Using Propensity Score Matching Analysis

Song JH, Wu HG, Keam BS, Hah JH, Ahn YC, Oh D, Noh JM, Park HJ, Lee CG, Keum KC, Cha J, Cho KH, Moon SH, Kim JY, Chung WK, Oh YT, Kim WT, Cho MJ, Kay CS, Kim YS

PURPOSE: We compared the treatment results and toxicity in nasopharyngeal carcinoma (NPC) patients treated with concurrent chemotherapy (CCRT) alone (the CRT arm) or neoadjuvant chemotherapy followed by CCRT (the NCT...
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Tumor Volume Reduction Rate during Adaptive Radiation Therapy as a Prognosticator for Nasopharyngeal Cancer

Lee H, Ahn YC, Oh D, Nam H, Noh JM, Park SY

PURPOSE: The purpose of this study is to evaluate the prognostic significance of the tumor volume reduction rate (TVRR) measured during adaptive definitive radiation therapy (RT) for nasopharyngeal cancer (NPC). MATERIALS...
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Prospective phase II trial of regional hyperthermia and whole liver irradiation for numerous chemorefractory liver metastases from colorectal cancer

Yu JI, Park HC, Choi DH, Noh JM, Oh D, Park JS, Chang JH, Kim ST, Lee J, Park SH, Park JO, Park YS, Lim HY, Kang WK

PURPOSE: A prospective phase II trial was conducted to evaluate the effectiveness and toxicity of regional hyperthermia and whole liver irradiation (WLI) for numerous chemorefractory liver metastases from colorectal cancer. MATERIALS...
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Radiation Therapy Alone in cT1-3N0 Non-small Cell Lung Cancer Patients Who Are Unfit for Surgical Resection or Stereotactic Radiation Therapy: Comparison of Risk-Adaptive Dose Schedules

Cho WK, Noh JM, Ahn YC, Oh D, Pyo H

PURPOSE: High dose definitive radiation therapy (RT) alone is recommended to patients with cT1-3N0 non-small cell lung cancer, who are unfit for surgery or stereotactic RT. This study was conducted...
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Effect of Radiation Therapy Techniques on Outcome in N3-positive IIIB Non-small Cell Lung Cancer Treated with Concurrent Chemoradiotherapy

Noh JM, Kim JM, Ahn YC, Pyo H, Kim B, Oh D, Ju SG, Kim JS, Shin JS, Hong CS, Park H, Lee E

PURPOSE: This study was conducted to evaluate clinical outcomes following definitive concurrent chemoradiotherapy (CCRT) for patients with N3-positive stage IIIB (N3-IIIB) non-small cell lung cancer (NSCLC), with a focus on...
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Carotid-Sparing TomoHelical 3-Dimensional Conformal Radiotherapy for Early Glottic Cancer

Hong CS, Oh D, Ju SG, Ahn YC, Noh JM, Chung K, Kim JS, Suh TS

PURPOSE: The purpose of this study was to investigate the dosimetric benefits and treatment efficiency of carotid-sparing TomoHelical 3-dimensional conformal radiotherapy (TH-3DCRT) for early glottic cancer. MATERIALS AND METHODS: Ten early-stage...
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Potential Role of Adjuvant Radiation Therapy in Cervical Thymic Neoplasm Involving Thyroid Gland or Neck

Noh JM, Ha SY, Ahn YC, Oh D, Seol SW, Oh YL, Han J

PURPOSE: The purpose of this study is to assess the clinicopathologic features, treatment outcomes, and role of adjuvant radiation therapy (RT) in cervical thymic neoplasm involving the thyroid gland or...
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Exome sequencing in a breast cancer family without BRCA mutation

Noh JM, Kim J, Cho DY, Choi DH, Park W, Huh SJ

PURPOSE: We performed exome sequencing in a breast cancer family without BRCA mutations. MATERIALS AND METHODS: A family that three sisters have a history of breast cancer was selected for analysis....
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The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center

Chung K, Han Y, Kim J, Ahn SH, Ju SG, Jung SH, Chung Y, Cho S, Jo K, Shin EH, Hong CS, Shin JS, Park S, Kim DH, Kim HY, Lee B, Shibagaki , Nonaka H, Sasai K, Koyabu Y, Choi C, Huh SJ, Ahn YC, Pyo HR, Lim DH, Park HC, Park W, Oh DR, Noh JM, Yu JI, Song S, Lee JE, Lee B, Choi DH

PURPOSE: The purpose of this report is to describe the proton therapy system at Samsung Medical Center (SMC-PTS) including the proton beam generator, irradiation system, patient positioning system, patient position...
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Treatment outcome of hepatic re-irradiation in patients with hepatocellular carcinoma

Seol SW, Yu JI, Park HC, Lim DH, Oh D, Noh JM, Cho WK, Paik SW

PURPOSE: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. MATERIALS AND METHODS: Between 1998 and 2011, 45 patients...
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Definitive Bimodality Concurrent Chemoradiotherapy in Patients with Inoperable N2-positive Stage IIIA Non-small Cell Lung Cancer

Noh JM, Ahn YC, Lee H, Pyo H, Kim B, Oh D, Park H, Lee E, Park K, Ahn JS, Ahn MJ, Sun JM

PURPOSE: This study was conducted to evaluate the treatment outcomes following definitive bimodality concurrent chemoradiotherapy (CCRT) in patients with inoperable N2-positive stage IIIA (N2-IIIA) non-small cell lung cancer (NSCLC). MATERIALS AND...
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