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Prevalence of idiopathic scoliosis in girls with central precocious puberty: effect of a gonadotropin-releasing hormone agonist

Chung LY, Nam HK, Rhie YJ, Huh R, Lee KH

Purpose: Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis and occurs in children between 10 to 18 years old, during periods of growth spurts and puberty changes....
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Thyroid function in girls with central precocious puberty

Jung G, Oh SB, Lee WY, Kim HR, Nam HK, Kim JH, Rhie YJ, Lee KH

PURPOSE: Obesity is a well-known risk factor for central precocious puberty (CPP). Recently, elevated thyroid stimulating hormone (TSH) was reported in obese youth. However, few data regarding the relationship between...
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Serum osteocalcin levels in overweight children

Oh SB, Lee WY, Nam HK, Rhie YJ, Lee KH

PURPOSE: Bone plays a role in glucose metabolism through the release of uncarboxylated osteocalcin into the systemic circulation. The identified novel roles for osteocalcin include increasing insulin secretion and sensitivity,...
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Low levels of 25-hydroxyvitamin D in children and adolescents with type 1 diabetes mellitus: a single center experience

Bae KN, Nam HK, Rhie YJ, Song DJ, Lee KH

PURPOSE: Low vitamin D level is common in adults with diabetes mellitus (DM). We assessed vitamin D level and its associated factors in Korean youth with type 1 DM. METHODS: Type...
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Small for gestational age and obesity: epidemiology and general risks

Nam HK, Lee KH

Children born small for gestational age (SGA) have several life-long consequences. Previous epidemiological studies investigated from childhood to adulthood reported that a number of chronic diseases originate in the prenatal...
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HbA1c Cutoff for Prediabetes and Diabetes Based on Oral Glucose Tolerance Test in Obese Children and Adolescents

Nam HK, Cho WK, Kim JH, Rhie YJ, Chung S, Lee KH, Suh BK

BACKGROUND: Oral glucose tolerance test (OGTT) is a traditional diagnostic tool for diabetes. Hemoglobin A1c (HbA1c) is an alternative method used in adults; however, its application in youths has been...
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Serum FGF21 Levels in Obese Korean Children and Adolescents

Baek J, Nam HK, Rhie YJ, Lee KH

BACKGROUND: Serum fibroblast growth factor 21 (FGF21) has been suggested to be a possible biomarker for early detection of metabolic syndrome and type 2 diabetes in adults. However, few studies...
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Serum Anti-Müllerian Hormone Levels in Precocious Puberty Girls according to Stage of GnRH Agonist Treatment

Nam HK, Kim HR, Rhie YJ, Lee KH

Few studies have investigated the long-term effects of gonadotropin-releasing hormone (GnRH) agonist treatment on the reproductive function of central precocious puberty (CPP) girls. In this cross-sectional study, we assessed the...
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Effect of xylobiose-sugar mixture on defecation frequency and symptoms in young women with constipation

Lee JS, Kim AR, Nam HK, Kyung M, Jo SE, Chang MJ

PURPOSE: The objective of the study was to investigate the effects of xylobiose-sugar mixture intake on defecation frequency and constipation symptoms in 31 young women with constipation. METHODS: Thirty-one subjects were...
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Treatment outcomes of gonadotropin-releasing hormone agonist in obese girls with central precocious puberty

Kim HR, Nam HK, Rhie YJ, Lee KH

PURPOSE: This study investigated the influence of obesity on the clinical course and effect of gonadotropin-releasing hormone analog (GnRHa) treatment in girls with central precocious puberty (CPP). METHODS: Medical records of...
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Genetic Variations of the KISS1R Gene in Korean Girls with Central Precocious Puberty

Oh YJ, Rhie YJ, Nam HK, Kim HR, Lee KH

The timing of puberty onset varies greatly among individuals, and much of this variation is modulated by genetic factors. This study aimed to identify the kisspeptin receptor (KISS1R) gene variations...
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Diabetic Ketoacidosis with Hyperglycemic Hyperosmolar State at the Onset of Type 2 Diabetes Mellitus in an Adolescent Male

Kim JH, Choi E, Rhie YJ, Lee JH, Lee KH, Nam HK

A hyperglycemic hyperosmolar state is usually associated with type 2 diabetes. It has significant mortality and morbidity and is rare in the pediatric population. We describe a rare case of...
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Qualitative assessment of precocious puberty-related user-created contents on YouTube

Nam HK, Bang SM, Rhie YJ, Park SH, Lee KH

PURPOSE: User-created content (UCC) has provided a considerable amount of medical information and become an important source. We aimed to evaluate the quality and scientific accuracy of precocious puberty-related UCC...
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A case of CHARGE syndrome featuring immunodeficiency and hypocalcemia

Son YY, Lee B, Suh CR, Nam HK, Lee JH, Hong YS, Lee JW

CHARGE syndrome (coloboma, heart defects, atresia choanae, retarded growth and development, genital hypoplasia, and ear abnormalities) is characterized by multiple malformations and is diagnosed using distinct consensus criteria. Mutations in...
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Pseudohypoaldosteronism in a newborn male with functional polymorphisms in the mineralocorticoid receptor genes

Jeong HA, Park YK, Jung YS, Nam MH, Nam HK, Lee KH, Rhie YJ

Hyponatremia and hyperkalemia in infancy can be attributed to various causes, originating from a variety of renal and genetic disorders. Pseudohypoaldosteronism type 1 (PHA1) is one of these disorders, causing...
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Age of menarche and near adult height after long-term gonadotropin-releasing hormone agonist treatment in girls with central precocious puberty

Baek JW, Nam HK, Jin D, Oh YJ, Rhie YJ, Lee KH

PURPOSE: Gonadotropin-releasing hormone agonist (GnRHa) is known for improving final adult height in patients with central precocious puberty (CPP). This study aimed to investigate the age of menarche and near...
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Influence of Bottle-Feeding on Serum Bisphenol A Levels in Infants

Rhie YJ, Nam HK, Oh YJ, Kim HS, Lee KH

Exposure to endocrine disrupting chemicals (EDCs), particularly during developmental periods, gives rise to a variety of adverse health outcomes. Bisphenol A (BPA) is a well-known EDC commonly found in plastic...
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Psychological characteristics of Korean children and adolescents with type 1 diabetes mellitus

Cho E, Shin SH, Eun SH, Kim JY, Nam HK, Lee KH, Rhie YJ

PURPOSE: This study investigates the behavioral and emotional characteristics of Korean children and adolescents with type 1 diabetes mellitus (T1DM) as compared to healthy controls, and examines whether their psychological...
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Factors to Predict Positive Results of Gonadotropin Releasing Hormone Stimulation Test in Girls with Suspected Precocious Puberty

Nam HK, Rhie YJ, Son CS, Park SH, Lee KH

Sometimes, the clinical findings and the results of the gonadotropin-releasing hormone (GnRH) stimulation test are inconsistent in girls with early breast development and bone age advancement. We aimed to investigate...
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Validity of Cough-Holter Monitoring for the Objective Assessment of Cough and Wheezing in Children with Respiratory Symptoms

Park HN, Jang WN, Nam HK, Kang IS, Seo SC, Bauer S, Choi IS, Choung JT, Yoo Y

  • KMID: 2315298
  • Pediatr Allergy Respir Dis.
  • 2012 Dec;22(4):344-353.
PURPOSE: Cough and wheezing are the most common respiratory symptoms in children. Recently, the cough-holter monitoring has been used to estimate the frequency and intensity of cough and wheezing, objectively....
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