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The Relationship of Caffeine Intake with Depression, Anxiety, Stress, and Sleep in Korean Adolescents

Jin MJ, Yoon CH, Ko HJ, Kim HM, Kim AS, Moon HN, Jung SP

BACKGROUND: In various studies in adults, caffeine may increase wakefulness and relieve pain, but caffeine overdose can cause many adverse serious effects on health. Caffeine intake has recently been increasing...
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Endocrine dysfunction after bone marrow transplantation during childhood and adolescence

Jin HY, Choi JH, Im HJ, Seo JJ, Moon HN, Yoo HW

PURPOSE: Several complications can occur in patients who received bone marrow transplantation (BMT) during childhood and adolescence. This study aims to investigate endocrine dysfunctions after BMT so that better care...
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Ototoxicity in children receiving cisplatin chemotherapy

Jang HJ, Cho HR, Lee JH, Bae KY, Seo JJ, Moon HN, Im HJ

PURPOSE: Cisplatin is highly effective for the treatment of solid tumors in children. However, the clinical use of cisplatin is limited by its ototoxicity. The aim of this study was...
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Unrelated Hematopoietic Stem Cell Transplantation for Children with Acute Leukemia: Experience at a Single Institution

Lee JH, Yoon HS, Song JS, Choi ES, Moon HN, Seo JJ, Im HJ

We evaluate the outcomes in children with acute leukemia who received allogeneic hematopoietic stem cell transplantation (HCT) using unrelated donor. Fifty-six children in complete remission (CR) received HCT from unrelated...
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Relationship between In Vitro Chemosensitivity assessed with MTT Assay and Clinical Outcomes in 103 Patients with Acute Leukemia

Jun KR, Jang S, Chi HS, Lee KH, Lee JH, Choi SJ, Seo JJ, Moon HN, Im HJ, Park CJ

BACKGROUND: Cellular drug resistance is supposed to play a major role in chemotherapy failure or relapse. The purpose of this study was to analyze the relationship between in vitro...
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Risk Factors of Bloodstream Infection Associated Mortality in Pediatric Patients with Hemato-oncologic Disease

Park HW, Youn HS, Im HJ, Kim MN, Seo JJ, Moon HN

BACKGROUND: Bloodstream infection is one of the important causes of mortality, and morbidity in pediatric patients with hemato-oncologic disease. The purpose of this study was to identify the risk factors...
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Outcome of Multicenter Study for Korean Children with Medulloblastoma

Park HJ, Nam BH, Lim HS, Shin HY, Hah JO, Kang HJ, Koo HH, Kook H, Kim DS, Kim SK, Kim IH, Kim JY, Ghim TT, Kim HK, Kim HS, Ra YS, Moon HN, Park KD, Park BK, Park SK, Park JE, Park JK, Baek HJ, Seo JJ, Suh CO, Sung KW, Shin HJ, Ahn SD, Ahn HS, Wang KC, Yoo KH, Ryu KH, Yoo ES, Lyu CJ, Lee KS, Lee SY, Lee YH, Lee JA, Lim DH, Im HJ, Chung NG, Jeong DC, Jung HL, Cho BK, Cho B, Choi EJ, Choi JU, Hwang TJ

  • KMID: 2279914
  • Clin Pediatr Hematol Oncol.
  • 2007 Oct;14(2):167-175.
PURPOSE: Medulloblastoma is the most common primary malignant brain tumor of childhood. In spite of improved multimodality approach, 30~40% of children with medulloblastoma still suffer from recurrence. Furthermore, many survivors...
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Treatment Outcome and Prognostic Factors for Children with Advanced Non-Hodgkin's Lymphoma at a Single Institution

Song JS, Youn HS, Im HJ, Ghim T, Moon HN, Seo JJ

BACKGROUND: Non-Hodgkin's lymphoma (NHL) accounts for over 80% of pediatric malignant lymphoma in Korea; the event free survival (EFS) of advanced stage NHL has been reported to be 60 to...
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Prognostic Significance of Multidrug Resistance Gene 1 (MDR1), Multidrug Resistance-related Protein (MRP) and Lung Resistance Protein (LRP) mRNA Expression in Acute Leukemia

Huh HJ, Park CJ, Jang S, Seo EJ, Chi HS, Lee JH, Lee KH, Seo JJ, Moon HN, Ghim T

The prognostic significance of multidrug resistance (MDR) gene expression is controversial. We investigated whether multidrug resistance gene 1 (MDR1), multidrug resistance-related protein (MRP) and lung resistance protein (LRP) mRNA expression...
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Current Status of Hematopoietic Stem Cell Transplantation in Korean Children

Jeong DC, Kang HJ, Koo HH, Kook H, Kim SY, Kim SK, Ghim T, Kim HK, Kim HM, Moon HN, Park KD, Park BK, Park SG, Park YS, Park HJ, Seo JJ, Sung KW, Shin HY, Ahn HS, Ryu KH, Ryu KH, Yoo ES, Lyu CJ, Lee KC, Lee SY, Lee YH, Lim YT, Lim JY, Jang PS, Jeon IS, Chung NG, Cho B, Hah JO, Hwang PH, Hwang TJ

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is one of the most important armamentarium against various hematologic malignancies or some solid tumors. We investigated the number of patients who might need...
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Prophylactic Low-dose Heparin or Prostaglandin E1 may Prevent Severe Veno-occlusive Disease of the Liver after Allogeneic Hematopoietic Stem Cell Transplantation in Korean Children

Song JS, Seo JJ, Moon HN, Ghim T, Im HJ

Studies investigating the effect of prophylactic drugs on hepatic veno-occlusive disease (VOD) development are rare in children that have undergone allogeneic hematopoietic stem cell transplantation (HSCT). This study examined risk...
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Hemophagocytic Syndrome Presenting as Severe Acute Hepatitis

Ryu JM, Chang SH, Kim JS, Lee JH, Lee MJ, Park KY, Kim KM, Seo JJ, Moon HN, Ghim T, Chi HS

  • KMID: 2275244
  • Korean J Pediatr Gastroenterol Nutr.
  • 2005 Sep;8(2):213-221.
PURPOSE: Hemophagocytic syndrome (HPS) is characterized by persistent high fever, hepatosplenomegaly, cytopenias, hypertriglyceridemia, and/or hypofibrinogenemia. Hepatic manifestations including overt hepatic failure and fulminant hepatitis are common in HPS. Liver transplantation...
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Treatment Outcome of Childhood B-cell Lymphoma and L3 Acute Lymphoblastic Leukemia from a Single Institution

Lim YJ, Kim YJ, Song JS, Lee MJ, Seo JJ, Moon HN, Ghim TT

  • KMID: 2278331
  • Korean J Pediatr Hematol Oncol.
  • 2005 Apr;12(1):28-39.
PURPOSE: High survival rate can be obtained in B-cell lymphoma (Burkitt's lymphoma, diffuse large B-cell lymphoma) and L3 acute lymphoblastic leukemia (ALL) with multiagent chemotherapy. Objectives of this study were...
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Hematopoietic Stem Cell Transplantation for Children with Malignant Lymphoma in Korea: Multicenter Retrospective Study

Kim BH, Won SC, Shin HY, Ahn HS, Hwang TJ, Kook H, Koo HH, Sung KW, Yoo KH, Kim HK, Cho B, Chung NG, Park JE, Hah JO, Ghim TT, Moon HN, Seo JJ, Park JS, Lee YH, Yoo ES, Lyu CJ

  • KMID: 2278330
  • Korean J Pediatr Hematol Oncol.
  • 2005 Apr;12(1):18-27.
PURPOSE: Children with Malignant lymphoma who is in the advanced stage at diagnosis or relapses during treatment have a poor prognosis. Recently, hematopoietic stem cell transplantation (HSCT) for advanced stage...
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Prognostic Significance of WT1 Gene Expression in Patients with Acute Leukemia

Huh HJ, Park CJ, Seo EJ, Chi HS, Lee JH, Lee KH, Seo JJ, Moon HN, Ghim T

  • KMID: 2038241
  • Korean J Lab Med.
  • 2005 Apr;25(2):78-84.
BACKGROUND: The Wilms' tumor gene (WT1) is located on chromosome 11p13. Several authors have shown that the expression of WT1 gene is associated with prognosis of acute leukemia. It was the...
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Epidemiology and Clinical Outcomes in Children with Malignant Lymphoma in Korea: Retrospective Study

Lyu CJ, Kang IJ, Koo HH, Kook H, Kim SK, Ghim TT, Kim HK, Kim HM, Kim HS, Moon HN, Park KD, Park KB, Park BK, Park SG, Park YS, Park JS, Park JE, Park HJ, Seo JJ, Sung KW, Shin HY, Ahn HS, Yang CH, Yoo KH, Ryu KH, Yoo ES, Lee KS, Lee KC, Lee SY, Lee YH, Lim YT, Jang PS, Chung NG, Jeong DC, Jung HL, Cho B, Choi YM, Hah JO, Han JW, Hwang TJ

  • KMID: 2278310
  • Korean J Pediatr Hematol Oncol.
  • 2004 Oct;11(2):153-163.
PURPOSE: Malignant lymphoma is the primary malignant tumor derived from lymphoid organs. It is composed of Hodgkin's disease and non-Hodgkin lymphoma. Recently, survival rate is on the rise due to...
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Recognition Survey of Radiation Exposure Risk for Physiatrist

Ko HY, Kwon DR, Moon HN

  • KMID: 2323805
  • J Korean Acad Rehabil Med.
  • 2003 Apr;27(2):265-268.
OBJECTIVE: To investigate recognition of radiation hazard by physiatrists involving in procedure under the roentgen environment. METHOD: We did the recognition survey using 12-item self administrated questionnaire over 2 months...
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Clinical Characteristics of Biphenotypic Acute Leukemia in Childhood: A Single Institutional Experience

Lee MJ, Seo JJ, Park CJ, Chi HS, Moon HN, Ghim TT

  • KMID: 2278264
  • Korean J Pediatr Hematol Oncol.
  • 2003 Apr;10(1):49-57.
PURPOSE: The diagnostic criteria of the biphenotypic acute leukemia (BAL) are based on the number and degree of the specificity of the immunological markers expressed on the leukemic blasts. The...
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Pediatric Myelodysplastic Syndrome in Korea: Clinical Characteristics and Comparison of Prognostic Scoring Systems

Kook H, Kim MK, Ghim TT, Moon HN, Park KD, Park HJ, Seo JJ, Shin HY, Ahn HS, Lee KS, Lee KC, Lee SY, Lee YH, Hwang PH, Hwang TJ

  • KMID: 2278257
  • Korean J Pediatr Hematol Oncol.
  • 2003 Apr;10(1):1-13.
PURPOSE: Myelodysplastic syndromes (MDS) are heterogeneous clonal stem cell disorders characterized by morphological and functional abnormal hematopoiesis, resulting in cytopenias in the peripheral blood. MDS in children are very rare...
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Autologous Stem Cell Transplantation for the Treatment of Neuroblastoma in Korea

Ryu KH, Ahn HS, Koo HH, Kook H, Kim MK, Kim HK, Ghim T, Moon HN, Seo JJ, Sung KW, Shin HY, Yoo ES, Lyu CJ, Lee YH, Lee H, Cho B, Cho HS, Choi HS, Hah JO, Hwang TJ

Autologous stem cell transplantation (ASCT) for the treatment of high-risk neuroblastoma (NBL) is an accepted method for restoring bone marrow depression after high dose chemotherapy. We retrospectively analyzed eighty eight...
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