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Association between Number of Retrieved Sentinel Lymph Nodes and Breast Cancer-related Lymphedema

Kim HK, Ju YW, Lee JW, Kim KE, Jung J, Kim Y, Lee HB, Moon HG, Noh DY, Seo KS, Han W

Purpose: Sentinel lymph node biopsy (SLNB) has become a standard axillary staging surgery for early breast cancer, and the proportion of patients requiring axillary lymph node dissection (ALND) is decreasing....
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Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test

Shin HC, Lee HB, Yoo TK, Lee ES, Kim RN, Park B, Yoon KA, Park C, Lee ES, Moon HG, Noh DY, Kong SY, Han W

Purpose Hereditary cancer syndrome means that inherited genetic mutations can increase a person's risk of developing cancer. We assessed the frequency of germline mutations using an nextgeneration sequencing (NGS)–based multiple-gene panel...
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Prognostic Role of Androgen Receptor Expression in Surgically Resected Early Breast Cancer Patients

Yang Y, Min A, Lee KH, Ryu HS, Kim TY, Woo Gu, Suh KJ, Lee DW, Lee HB, Moon HG, Han W, Park IA, Noh DY, Im SA

Purpose: Endocrine therapy is a standard treatment for hormone receptor-positive breast cancer, which accounts for 60%–75% of all breast cancer. Hormone receptor positivity is a prognostic and predictive biomarker in...
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Protein Phosphatase 1H, Cyclin-Dependent Kinase Inhibitor p27, and Cyclin-Dependent Kinase 2 in Paclitaxel Resistance for Triple Negative Breast Cancers

Hur S, Kim JH, Yun J, Ju YW, Han JM, Heo W, Kim K, Jeong K, Lee HB, Han W, Noh DY, Kim JI, Moon HG

Purpose: Paclitaxel is a cytotoxic chemotherapy commonly used in patients with triple negative breast cancer (TNBC); however, the resistance to paclitaxel is a cause of poor response in the patients....
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Erratum: A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer

Kim Y, Kang UB, Kim S, Lee HB, Moon HG, Han W, Noh DY

In the article, “A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer” in Volume 22(4), page 579-586 was error in the table. In Table 1,...
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A survey investigating the current situation of the international visiting scholar program at the department of surgery in Korea

Ryoo SB, Park H, Han YD, Moon HG, Kim HJ, Yoon KC, Bae J, Park YJ, Cho JY, Jeong WK, Jeong SY, On Behalf of the International Affairs Committee of the Korean Surgical Society

Purpose: The number of international visiting scholars has been on the increase in Korea and we aim to investigate the program’s current situation. Methods: This cross-sectional study is based on an...
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Efficacy of quick Sequential Organ Failure Assessment with lactate concentration for predicting mortality in patients with community-acquired pneumonia in the emergency department

Song H, Moon HG, Kim SH

OBJECTIVE: Community-acquired pneumonia (CAP) is a major cause of sepsis, and sepsis-related acute organ dysfunction affects patient mortality. Although the quick Sequential Organ Failure Assessment (qSOFA) is a new screening...
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A Validation Study of a Multiple Reaction Monitoring-Based Proteomic Assay to Diagnose Breast Cancer

Kim Y, Kang UB, Kim S, Lee HB, Moon HG, Han W, Noh DY

PURPOSE: Currently, the standard screening tool for breast cancer is screening mammography. There have been many efforts to develop a blood-based diagnostic assay for breast cancer diagnosis; however, none have...
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Immediate Breast Reconstruction vs. Mastectomy Alone in Locally Advanced Breast Cancer; Local Recurrence and Distant Recurrence

Kim Y, Lee ES, Cheun JH, Jung J, Lee HB, Moon HG, Noh DY, Han W

PURPOSE: The oncologic safety of immediate breast reconstruction (IBR) has been demonstrated. However, the outcome of IBR for locally advanced breast cancer (LABC) is still under debate. We compared the...
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Efficacy of Mastocheck for Screening of Early Breast Cancer: Comparison with Screening Mammography

Kim Y, Moon HG, Lee HB, Moon WK, Cho N, Chang JM, Han W, Noh DY

PURPOSE: This study was designed to verify the effectiveness of Mastocheck, a new diagnostic tool developed with proteomics techniques using plasma proteins. In addition, checked the current state of mammography...
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Landscape of Actionable Genetic Alterations Profiled from 1,071 Tumor Samples in Korean Cancer Patients

Lee SH, Lee B, Shim JH, Lee KW, Yun JW, Kim SY, Kim TY, Kim YH, Ko YH, Chung HC, Yu CS, Lee J, Rha SY, Kim TW, Jung KH, Im SA, Moon HG, Cho S, Kang JH, Kim J, Kim SK, Ryu HS, Ha SY, Kim JI, Chung YJ, Kim C, Kim HL, Park WY, Noh DY, Park K

PURPOSE: With the emergence of next-generation sequencing (NGS) technology, profiling a wide range of genomic alterations has become a possibility resulting in improved implementation of targeted cancer therapy. In Asian...
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Endocrine Treatment-Related Symptoms and Patient Outcomes in Breast Cancer: A Meta-Analysis

Yoo TK, Jang MJ, Lee E, Moon HG, Noh DY, Han W

PURPOSE: An association between endocrine treatment-related symptoms and breast cancer recurrence has been suggested previously; however, conflicting results have been reported. We performed a meta-analysis of published studies to clarify...
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The Effect of Reproductive Factors on Breast Cancer Presentation in Women Who Are BRCA Mutation Carrier

Kim JY, Moon HG, Kang YJ, Han W, Noh WC, Jung Y, Moon BI, Kang E, Park SS, Lee MH, Park BY, Lee JW, Noh DY

PURPOSE: Germline mutations in the BRCA1 and BRCA2 genes confer increased risks for breast cancers. However, the clinical presentation of breast cancer among women who are carriers of the BRCA1...
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Efficacy of Letrozole as First-Line Treatment of Postmenopausal Women with Hormone Receptor–Positive Metastatic Breast Cancer in Korea

Beom SH, Oh J, Kim TY, Lee KH, Yang Y, Suh KJ, Moon HG, Han SW, Oh DY, Han W, Kim TY, Noh DY, Im SA

PURPOSE: Letrozole showed efficacy and generally favorable toxicities, along with the convenience of oral administration in postmenopausal patients with hormone receptor (HR)–positive metastatic breast cancer (MBC). To the best of...
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Prognostic Influence of BCL2 on Molecular Subtypes of Breast Cancer

Hwang KT, Han W, Kim J, Moon HG, Oh S, Song YS, Kim YA, Chang MS, Noh DY

PURPOSE: We aimed to reveal the prognostic influence of B-cell CLL/lymphoma 2 (BCL2) on molecular subtypes of breast cancer. METHODS: We analyzed 9,468 patients with primary breast cancer. We classified molecular...
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Actual Conversion Rate from Total Mastectomy to Breast Conservation after Neoadjuvant Chemotherapy for Stages II–III Breast Cancer Patients

Mo H, Kim Y, Rhu J, Lee KH, Kim TY, Im SA, Lee ES, Lee HB, Moon HG, Noh DY, Han W

PURPOSE: Neoadjuvant chemotherapy (NCT) is a treatment modality that increases the breast-conserving rate in breast cancer. This prospective study was performed to evaluate the actual breast-conserving rate using NCT in...
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Can We Skip Intraoperative Evaluation of Sentinel Lymph Nodes? Nomogram Predicting Involvement of Three or More Axillary Lymph Nodes before Breast Cancer Surgery

Ahn SK, Kim MK, Kim J, Lee E, Yoo TK, Lee HB, Kang YJ, Kim J, Moon HG, Chang JM, Cho N, Moon WK, Park IA, Noh DY, Han W

PURPOSE: The American College of Surgeons Oncology Group Z0011 trial reported that complete dissection of axillary lymph nodes (ALNs) may not be warranted in women with clinical T1-T2 tumors and...
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Patients with Concordant Triple-Negative Phenotype between Primary Breast Cancers and Corresponding Metastases Have Poor Prognosis

Shin HC, Han W, Moon HG, Park IA, Noh DY

PURPOSE: We investigated the prognostic impact of discordance between the receptor status of primary breast cancers and corresponding metastases. METHODS: A total 144 patients with breast cancer and distant metastasis were...
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Delay of Treatment Initiation Does Not Adversely Affect Survival Outcome in Breast Cancer

Yoo TK, Han W, Moon HG, Kim J, Lee JW, Kim MK, Lee E, Kim J, Noh DY

PURPOSE: Previous studies examining the relationship between time to treatment and survival outcome in breast cancer have shown inconsistent results. The aim of this study was to analyze the overall...
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Analysis of the Relationship between Body Mass Index and Breast Cancer Incidence in Korean Women

Kang HS, Han J, Kim J, Lee HB, Shin HC, Han W, Noh DY, Moon HG

PURPOSE: Obesity in women has been shown to have correlation with breast cancer incidence. The proportion of Korean women who are obese has increased recently. However, there is no large-scale...
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