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Induction of GDNF and GFRα-1 Following AAV1-Rheb(S16H) Administration in the Hippocampus in vivo

Yun D, Jeon MT, Kim HJ, Moon GJ, Lee S, Ha CM, Shin M, Kim SR

  • KMID: 2500527
  • Exp Neurobiol.
  • 2020 Apr;29(2):164-175.
  • doi: 10.5607/en19075
The activation of neurotrophic signaling pathways following the upregulation of glial cell line-derived neurotrophic factor (GDNF), a member of the transforming growth factor-β family, has a potential neuroprotective effect in...
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Morin Prevents Granule Cell Dispersion and Neurotoxicity via Suppression of mTORC1 in a Kainic Acid-induced Seizure Model

Lee JM, Hong J, Moon GJ, Jung UJ, Won SY, Kim SR

An abnormal reorganization of the dentate gyrus and neurotoxic events are important phenotypes in the hippocampus of patients with temporal lobe epilepsy (TLE). The effects of morin, a bioflavonoid constituent...
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Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo

Kim S, Moon GJ, Oh YS, Park J, Shin WH, Jeong JY, Choi KS, Jin BK, Kholodilov N, Burke RE, Kim HJ, Ha CM, Lee SG, Kim SR

We recently reported that adeno-associated virus serotype 1 (AAV1) transduction of murine nigral dopaminergic (DA) neurons with constitutively active ras homolog enriched in brain with a mutation of serine to...
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Adult Stem Cell Therapy for Stroke: Challenges and Progress

Bang OY, Kim EH, Cha JM, Moon GJ

Stroke is one of the leading causes of death and physical disability among adults. It has been 15 years since clinical trials of stem cell therapy in patients with stroke...
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Role of High-Resolution Magnetic Resonance Imaging in the Diagnosis of Primary Angiitis of the Central Nervous System

Noh HJ, Choi JW, Kim JP, Moon GJ, Bang OY

BACKGROUND: Primary angiitis of the central nervous system (PACNS) is a rare disorder and is often difficult to diagnose due to the lack of a confirmatory test. PACNS can generally...
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Acute Carbon Monoxide Poisoning: Prognostic Factors for Delayed Neuropsychiatric Sequelae

Moon GJ, Kim GT

  • KMID: 2333836
  • J Korean Soc Emerg Med.
  • 2014 Jun;25(3):268-276.
PURPOSE: Delayed neuropsychiatric sequelae (DNS), which are thought to arise from delayed post-hypoxic leukoencephalopathy, commonly occur after recovery from acute carbon monoxide (CO) poisoning. This study was conducted in order...
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Antioxidant Effects of Statins in Patients with Atherosclerotic Cerebrovascular Disease

Moon GJ, Kim SJ, Cho YH, Ryoo S, Bang OY

BACKGROUND AND PURPOSE: Oxidative stress is involved in the pathophysiological mechanisms of stroke (e.g., atherosclerosis) and brain injury after ischemic stroke. Statins, which inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, have...
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Biomarkers for Stroke

Kim SJ, Moon GJ, Bang OY

  • KMID: 2223736
  • J Stroke.
  • 2013 Jan;15(1):27-37.
BACKGROUND: Major stroke clinical trials have failed during the past decades. The failures suggest the presence of heterogeneity among stroke patients. Biomarkers refer to indicators found in the blood, other...
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Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice

Lee JH, Won SM, Suh J, Son SJ, Moon GJ, Park UJ, Gwag BJ

The endoplasmic reticulum (ER) stress results from disrupted protein folding triggered by protein mutation or oxidation, reduced proteasome activity, and altered Ca2+ homeostasis. ER stress is accompanied by activation of...
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A Review Study on the Application of Biotechongy for Man and Human Right

Moon GJ

  • KMID: 2305522
  • Korean J Leg Med.
  • 1998 Oct;22(2):91-94.
The application of new biotechnology has developed with tremendous speed, and DNA technology has created ethical problems related human right, such as early diagnosis, mass screening, prenatal diagnosis, carrier detection...
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The Last Fifty Years of Western Medicine in Korea: Korean Society for Legal Medicine

Moon GJ

  • KMID: 1536401
  • J Korean Med Assoc.
  • 1997 Aug;40(8):972-975.
No abstract available.
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The Conceptional Difference on the Postmortem Examination of Poisoning in the East and West

Moon GJ

  • KMID: 2082602
  • Korean J Leg Med.
  • 1997 May;21(1):11-16.
Utilization of medical knowledge during legal proceeding began in the seventeenth century, but its role is quite different between the East and West. Traditional oriental medicine is based on principles of...
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The problems of duty to affirm medical procedures and used materials in medical cares

Moon GJ

  • KMID: 1928247
  • Korean J Leg Med.
  • 1993 May;17(1):16-23.
No abstract available.
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Medicolegal investigation od sexual assault victims

Moon GJ

  • KMID: 1694598
  • Korean J Leg Med.
  • 1992 Oct;16(2):1-10.
No abstract available.
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Individual identification of human bloodstrains by genetic manipulation-DNA fingerprinting

Moon GJ, Hwang JJ, Kim CY, Park EU

  • KMID: 1694535
  • Korean J Leg Med.
  • 1991 May;15(1):14-23.
No abstract available.
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Verification of suicide and psychological autopsy

Moon GJ

  • KMID: 1694533
  • Korean J Leg Med.
  • 1991 May;15(1):1-13.
No abstract available.
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Medicolegal aspect on medical misdiagnosis

Moon GJ

  • KMID: 1694580
  • Korean J Leg Med.
  • 1991 Oct;15(2):75-86.
No abstract available.
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The Right of Ingeritance and Family Name of Embryo by Artificial Conception (53)

Moon GJ

  • KMID: 1683595
  • J Korean Pediatr Soc.
  • 1990 Sep;33(9):1312-1312.
No abstract available.
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The Right of Ingeritance and Family Name of Embryo by Artificial Conception (52)

Moon GJ

  • KMID: 1683537
  • J Korean Pediatr Soc.
  • 1990 Aug;33(8):1166-1167.
No abstract available.
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The Right of Ingeritance and Family Name of Embryo by Artificial Conception (51)

Moon GJ

  • KMID: 1683486
  • J Korean Pediatr Soc.
  • 1990 Jul;33(7):1024-1025.
No abstract available.
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