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Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells

Kim J, Lee KP, Kim BS, Lee SJ, Moon BS, Baek S

Luminespib (AUY922), a heat shock proteins 90 inhibitor, has anti-neoplastic and antitumor effects. However, it is not clear whether AUY922 affects events in vascular diseases. We investigated the effects of...
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Venous Aneurysm in Superficial Venous Palmar Arch: A Case Report

Kim S, Park HS, Moon BS

Venous aneurysms in the upper limbs are a rare disease and are often misdiagnosed as benign tumors of soft tissues. Conservative treatment is considered in the absence of symptoms caused...
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Combination of In Vivo [¹²³I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Park SH, Song YS, Moon BS, Lee BC, Park HS, Kim SE

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [¹²³I]FP-CIT assesses changes in synaptic DA availability when endogenous...
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Lactobacillus plantarum-derived Extracellular Vesicles Protect Atopic Dermatitis Induced by Staphylococcus aureus-derived Extracellular Vesicles

Kim MH, Choi SJ, Choi HI, Choi JP, Park HK, Kim EK, Kim MJ, Moon BS, Min TK, Rho M, Cho YJ, Yang S, Kim YK, Kim YY, Pyun BY

PURPOSE: The microbial environment is an important factor that contributes to the pathogenesis of atopic dermatitis (AD). Recently, it was revealed that not only bacteria itself but also extracellular vesicles...
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The Presence of Neural Stem Cells and Changes in Stem Cell-Like Activity With Age in Mouse Spiral Ganglion Cells In Vivo and In Vitro

Moon BS, Ammothumkandy A, Zhang N, Peng L, Ibrayeva A, Bay M, Pratap A, Park HJ, Bonaguidi , Lu W

OBJECTIVES: Spiral ganglion neurons (SGNs) include potential endogenous progenitor populations for the regeneration of the peripheral auditory system. However, whether these populations are present in adult mice is largely unknown....
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Therapeutic effects of orally administered CJLP55 for atopic dermatitis via the regulation of immune response

Hyung KE, Kim SJ, Jang YW, Lee DK, Hyun KH, Moon BS, Kim B, Ahn H, Park SY, Sohn UD, Park ES, Hwang KW

Atopic dermatitis (AD) is an inflammatory skin condition accompanied by symptoms such as edema and hemorrhage. Kimchi is a traditional fermented Korean dish consisting of various probiotics. In this study,...
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Effect of fermented soybean products intake on the overall immune safety and function in mice

Lee JH, Paek SH, Shin HW, Lee SY, Moon BS, Park JE, Lim GD, Kim CY, Heo Y

Various functional activities have been reported for the fermented soybean products doenjang (DJ) and cheonggukjang (CGJ), although no systemic investigations of their immune functions have been conducted to date. We...
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Eligibility for Statin Treatment in Korean Subjects with Reduced Renal Function: An Observational Study

Moon BS, Kim J, Kim JH, Hyun YY, Park SE, Oh HG, Park CY, Lee WY, Oh KW, Lee KB, Kim H, Park SW, Rhee EJ

BACKGROUND: The purpose of this study was to investigate the relationship between statin eligibility and the degree of renal dysfunction using the Adult Treatment Panel (ATP) III and the American...
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The Relationship between 10-Year Cardiovascular Risk Calculated Using the Pooled Cohort Equation and the Severity of Non-Alcoholic Fatty Liver Disease

Lee JI, Kim MC, Moon BS, Song YS, Han EN, Lee HS, Son Y, Kim J, Han EJ, Park HJ, Park SE, Park CY, Lee WY, Oh KW, Park SW, Rhee EJ

BACKGROUND: We investigated the association between the severity of non-alcoholic fatty liver disease (NAFLD) and the estimated 10-year risk of cardiovascular disease (CVD) calculated by Pooled Cohort Equation (PCE) and...
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Dual effects of a mixture of grape pomace (Campbell Early) and Omija fruit ethanol extracts on lipid metabolism and the antioxidant defense system in diet-induced obese mice

Han HJ, Jung UJ, Kim HJ, Moon BS, Cho SJ, Park YB, Lee DG, Choi MS

BACKGROUND/OBJECTIVES: We investigated the effects of a combination of grape pomace (Vitis labrusca, Campbell Early) and Omija fruit (Schizandra chinensis, Baillon) ethanol extracts on lipid metabolism and antioxidant defense system...
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Metabolic Health Is More Important than Obesity in the Development of Nonalcoholic Fatty Liver Disease: A 4-Year Retrospective Study

Lee MK, Rhee EJ, Kim MC, Moon BS, Lee JI, Song YS, Han EN, Lee HS, Son Y, Park SE, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: The aim of this study is to compare the risk for future development of nonalcoholic fatty liver disease (NAFLD) according to different status of metabolic health and obesity. METHODS: A...
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Analysis of Gene Mutations Associated with Antibiotic Resistance in Helicobacter pylori Strains Isolated from Korean Patients

An B, Moon BS, Lim HC, Lee YC, Kim H, Lee G, Kim SH, Park M, Kim JB

BACKGROUND/AIMS: This study aims to identify the gene mutation pattern associated with antibiotic resistance for mainly used antibiotics in Helicobacter pylori strains isolated from Koreans. MATERIALS AND METHODS: Seventy-one H. pylori...
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Effects of coagulation factor concentrate prophylaxis in moderate and severe hemophilia A patients at a single hemophilia center in Korea

Moon BS, Choi JS, You CW

PURPOSE: The aim of this study was to investigate prophylactic treatment effects in Korean patients with severe hemophilia A. METHODS: A prospective study of 32 severe hemophilia A patients was conducted...
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Antibiotic Resistance in Helicobacter pylori Strains and its Effect on H. pylori Eradication Rates in a Single Center in Korea

An B, Moon BS, Kim H, Lim HC, Lee YC, Lee G, Kim SH, Park M, Kim JB

BACKGROUND: Clarithromycin, amoxicillin, metronidazole, tetracycline, and levofloxacin have been commonly used for the eradication of Helicobacter pylori. We compared the change in antibiotic resistance of H. pylori strains during two...
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Measurements and Comparative Considerations of Velocities of Primary Bloodstain Spatters using a High Speed Camera

Seo YI, Moon BS, Cho YJ, Jeon WJ, Kim SJ, Son BN, Kim KJ, Kim YG, Choo CW, Lee SH, Hong WH, Lim CW, Lee JH, Ryu KJ, Yu JS, Choi YS, Park NK

  • KMID: 1849319
  • Korean J Leg Med.
  • 2011 May;35(1):27-31.
Bloodstain pattern analysis is a forensic discipline that reconstruct events of a crime scene by analyzing sizes, shapes, distributions, positions of bloodstains. Bloodstain pattern can be classified into the low...
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Practice Pattern of Gastroenterologists for the Management of GERD Under the Minimal Influence of the Insurance Reimbursement Guideline: A Multicenter Prospective Observational Study

Lee KJ, Kim JI, Park JS, Moon BS, Kim SG, Chun JH, Jung HY, Choi CH, Chun SW, Song GA, Choi MG, Chun HJ

The objective of the study was to document practice pattern of gastroenterologists for the management of gastroesophageal reflux disease (GERD) under the minimal influence of the insurance reimbursement guideline. Data...
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A Study of Similarities Between Bloodstain Pattern Analysis and Fire Investigation In Point View of Event Analysis

Seo YI, Moon BS, Cho YJ, Jeon WJ, Park JJ, Kim SJ, Choi YS, Park NK

  • KMID: 2305486
  • Korean J Leg Med.
  • 2010 Nov;34(2):116-124.
Crime scene reconstruction is the use of scientific methods, physical evidence, deductive and inductive reasoning and their interrelationships to gain explicit knowledge of the series of events that surround the...
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A Novel Aromatic Fluorine-18 Labeling Method Using Iodonium Salts Precursor

Moon BS, Lee BC, Kim SE

  • KMID: 2313063
  • Nucl Med Mol Imaging.
  • 2009 Feb;43(1):1-9.
As many new drug substances contained various aromatic rings and fluorine attached to an electron rich aromatic ring or on the meta-position, a strategy towards improvement in aromatic fluorination of...
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Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway

Moon BS, Yoon JY, Kim MY, Lee SH, Choi T, Choi KY

Bone morphogenic protein 4 (BMP4), a member of the TGF-beta superfamily, induced neural differentiation of neural stem cells (NSCs) grown in a medium containing basic fibroblast growth factor (bFGF). The...
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Phase III Clinical Trial of Revaprazan (Revanex(R)) for Gastric Ulcer

Chang R, Chung IS, Park SH, Kim SK, Choi SR, Song GA, Hahm KB, Lee YC, Kim HS, Kim TN, Choi SC, Seol SY, Rew JS, Kim DJ, Lee J, Choi HS, Lee JE, Song GS, Moon BS, Joo SA

  • KMID: 2243200
  • Korean J Gastrointest Endosc.
  • 2007 Jun;34(6):312-319.
BACKGROUND/AIMS: This randomized, double-blind, phase III, multicenter trial was carried out to compare the efficacy and safety of revaprazan, a novel acid pump antagonist, with that of omeprazole in patients...
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