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Long-term changes in lean mass in postmenopausal women and the effects of osteoporosis pharmacotherapy: A 10-year longitudinal study

Miyakoshi N, Hongo M, Shimada Y

Objectives: Although sarcopenia is diagnosed using appendicular lean mass (ALM), only a few long-term studies on changes in both ALM and bone mineral density (BMD) have been reported. The purposes...
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Impact of appendicular and trunk skeletal muscle mass and back extensor strength on sagittal spinal alignment in Japanese women without vertebral fracture

Kudo D, Miyakoshi N, Hongo M, Kasukawa Y, Ishikawa Y, Mizutani T, Mizutani Y, Shimada Y

Objectives: Progressive and generalized loss of skeletal muscle mass (SMM) and strength are characteristics of sarcopenia. However, the impact of appendicular and trunk SMM and back extensor strength (BES) on...
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Effects of teriparatide on bone in autochthonous transgenic model mice for diabetes mellitus (Akita mice)

Ohuchi K, Miyakoshi , Kasukawa Y, Segawa T, Kinoshita , Sato C, Fujii M, Shimada Y

OBJECTIVES: The purpose of this study is to evaluate the effects of teriparatide (TPTD) on bone mineral density (BMD), bone strength, and bone quality in Akita mouse models of diabetes...
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Surgical Results of Patients with Myelopathy due to Ossification of the Ligamentum Flavum with Ossification of the Posterior Longitudinal Ligament or a Vertebral Fracture at the Same Level of the Thoracic Spine: A Retrospective Comparative Study

Kasukawa Y, Miyakoshi , Hongo M, Ishikawa Y, Kudo D, Kimura R, Ono Y, Iida J, Sato C, Shimada Y

STUDY DESIGN: Retrospective and comparative study. PURPOSE: We assessed surgical treatment outcomes in patients with thoracic myelopathy due to ossification of the ligamentum flavum (OLF), and OLF combined with ossification of...
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Short-Term Results of Hybrid Closed-Wedge High Tibial Osteotomy: A Case Series with a Minimum 3-Year Follow-up

Saito H, Saito K, Shimada Y, Yamamura T, Yamada S, Sato T, Nozaka K, Kijima H, Miyakoshi

PURPOSE: High tibial valgus osteotomy (HTO) is a well-established surgical procedure for patients with medial compartment osteoarthritis (OA) of the knee. The hybrid closed-wedge HTO (CWHTO) procedure permits extensive correction...
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Effects of eldecalcitol and ibandronate on secondary osteoporosis and muscle wasting in rats with adjuvant-induced arthritis

Ono Y, Miyakoshi , Kasukawa Y, Nagasawa H, Tsuchie H, Akagawa M, Nagahata I, Yuasa Y, Sato C, Shimada Y

OBJECTIVES: Rheumatoid arthritis (RA) is characterized by chronic inflammation of the synovium, progressive erosion of the articular cartilage, and joint destruction. RA also causes secondary osteoporosis and muscle wasting. We...
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Age-Related Prevalence of Periodontoid Calcification and Its Associations with Acute Cervical Pain

Kobayashi , Miyakoshi , Konno N, Ishikawa Y, Noguchi H, Shimada Y

STUDY DESIGN: Prospective study. PURPOSE: To assess the prevalence of periodontoid calcification and its associations with acute cervical pain. OVERVIEW OF LITERATURE: Calcium pyrophosphate dihydrate (CPPD) deposition disease is a common rheumatological...
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Evaluation of Sagittal Spine-Pelvis-Lower Limb Alignment in Elderly Women with Pelvic Retroversion while Standing and Walking Using a Three-Dimensional Musculoskeletal Model

Sasaki K, Hongo M, Miyakoshi , Matsunaga , Yamada S, Kijima H, Shimada Y

STUDY DESIGN: In vivo biomechanical study using a three-dimensional (3D) musculoskeletal model for elderly individuals with or without pelvic retroversion. PURPOSE: To evaluate the effect of pelvic retroversion on the sagittal...
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Effects of combined therapy of alendronate and low-intensity pulsed ultrasound on metaphyseal bone repair after osteotomy in the proximal tibia of glucocorticoid-induced osteopenia rats

Kawano T, Miyakoshi , Kasukawa Y, Hongo M, Tsuchie H, Sato C, Fujii M, Suzuki M, Akagawa M, Ono Y, Yuasa Y, Nagahata I, Shimada Y

OBJECTIVES: Glucocorticoid (GC) treatment inhibits activation of runt-related transcription factor 2 (Runx2), which is essential for osteoblast differentiation from stem cells. As a result, GC treatment results in bone loss,...
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Perioperative Medical Complications after Posterior Approach Spinal Instrumentation Surgery for Osteoporotic Vertebral Collapse: A Comparative Study in Patients with Primary Osteoporosis and Those with Secondary Osteoporosis

Miyakoshi , Kobayashi , Suzuki T, Kikuchi K, Kasukawa Y, Shimada Y

STUDY DESIGN: A retrospective comparative study. PURPOSE: To compare perioperative medical complications after posterior approach spinal instrumentation surgery for osteoporotic vertebral collapse (OVC) between patients with primary osteoporosis and those with...
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Occurrence of vertebral fracture more closely associated with decreased anteroposterior than lateral lumbar bone mineral density

Tsuchie H, Miyakoshi , Kasukawa Y, Nishi T, Abe H, Segawa T, Shimada Y

  • KMID: 2309514
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):38-40.
OBJECTIVES: While it has been pointed out that an anteroposterior (AP) view of the lumbar spine may lead to overestimation of the bone mineral density (BMD), a lateral view is...
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Combined treatment with minodronate and vitamin C increases bone mineral density and strength in vitamin C-deficient rats

Segawa T, Miyakoshi , Kasukawa Y, Aonuma H, Tsuchie H, Shimada Y

  • KMID: 2309513
  • Osteoporos Sarcopenia.
  • 2016 Mar;2(1):30-37.
OBJECTIVES: Reduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study...
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Short-Term Results of Transforaminal Lumbar Interbody Fusion Using Pedicle Screw with Cortical Bone Trajectory Compared with Conventional Trajectory

Kasukawa Y, Miyakoshi , Hongo M, Ishikawa Y, Kudo D, Shimada Y

STUDY DESIGN: Case-control study. PURPOSE: To evaluate clinical and radiological results of transforaminal lumbar interbody fusion (TLIF) performed with cortical bone trajectory (CBT) pedicle screw insertion with those of TLIF using...
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Comparison between Bilateral C2 Pedicle Screwing and Unilateral C2 Pedicle Screwing, Combined with Contralateral C2 Laminar Screwing, for Atlantoaxial Posterior Fixation

Miyakoshi , Hongo M, Kobayashi , Suzuki T, Abe E, Shimada Y

STUDY DESIGN: A retrospective study. PURPOSE: To compare clinical and radiological outcomes between bilateral C2 pedicle screwing (C2PS) and unilateral C2PS, combined with contralateral C2 laminar screwing (LS), for posterior atlantoaxial...
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Anterior Decompression and Shortening Reconstruction with a Titanium Mesh Cage through a Posterior Approach Alone for the Treatment of Lumbar Burst Fractures

Suzuki T, Abe E, Miyakoshi , Murai H, Kobayashi , Abe T, Kikuchi K, Shimada Y

STUDY DESIGN: A retrospective study. PURPOSE: To examine the efficacy and safety for a posterior-approach circumferential decompression and shortening reconstruction with a titanium mesh cage for lumbar burst fractures. OVERVIEW OF LITERATURE:...
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