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Concordance of Programmed DeathLigand 1 Expression between SP142 and 22C3/SP263 Assays in Triple-Negative Breast Cancer

Lee SE, Park HY, Lim SD, Han HS, Yoo YB, Kim WS

Purpose: Triple-negative breast cancer (TNBC) represents a major clinical challenge due to its aggressive and metastatic behavior and the lack of available targeted therapies. Therefore, therapeutic strategies are needed to...
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A Treatment of Basal cell Carcinoma on the Face of a Xeroderma Pigmentosum Patient: A Case Report

Bae J, Jun D, Kim J, Lee M, Shin D, Lim SD, Choi H

Xeroderma pigmentosum is a rare autosomal recessive disease, related to defects in DNA repair mechanism. It presents skin lesions on sun-exposed areas, leading to various skin cancer. Skin lesions can...
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Ganglioneuroma of the Sacrum

Lee D, Choe WJ, Lim SD

Presacral ganglioneuromas are extremely rare benign tumors and fewer than 20 cases have been reported in the literature. Ganglioneuromas are difficult to be differentiated preoperatively from tumors such as schwannomas,...
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Relationship of Renal Echogenicity with Renal Pathology and Function

Lee JH, Cho MH, Chung SI, Lim SD, Kim KS

PURPOSE: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known. METHODS: Ultrasound...
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BRAF-Mutated Colorectal Cancer Exhibits Distinct Clinicopathological Features from Wild-Type BRAF-Expressing Cancer Independent of the Microsatellite Instability Status

Jang MH, Kim S, Hwang DY, Kim WY, Lim SD, Kim WS, Hwang TS, Han HS

In patients with colorectal cancer (CRC), the BRAF V600E mutation has been reported to be associated with several clinicopathological features and poor survival. However, the prognostic implications of BRAF V600E...
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Hepatic Immunoglobulin G4-related Inflammatory Pseudotumor Mimicking Hepatocellular Carcinoma

Kang SH, Park SH, Park HH, Lee JR, Choe WH, Lim SD, Ko SY

Immunoglobulin G4-related disease is a recently recognized entity characterized by a mass-forming or regional lesion that contains an extensive infiltration of IgG4-producing plasma cells with dense fibrosis. Immunoglobulin G4-related disease...
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Effect of low-dose valsartan on proteinuria in normotensive immunoglobulin A nephropathy with minimal proteinuria: a randomized trial

Jo YI, Na HY, Moon JY, Han SW, Yang DH, Lee SH, Park HC, Choi HY, Lim SD, Kie JH, Lee YK, Shin SK

BACKGROUND/AIMS: Immunoglobulin A nephropathy (IgAN) is a generally progressive disease, even in patients with favorable prognostic features. In this study, we aimed to investigate the antiproteinuric effect and tolerability of...
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Gastric carcinosarcoma

Park MY, Bang HY, Han DS, Lim SD, Kim JH, Yoon SY, Kim PS

Gastric carcinosarcoma is an uncommon biphasic malignant tumor. We report the case of 59-year-old man with a history of melena and dizziness. Endoscopic findings showed a fungating mass that originated...
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Metastatic Intracranial Hemangiopericytoma to the Spinal Column: A Case Report

Joo MS, Rho YJ, Song SW, Koh YC, Roh HG, Lim SD

Intracranial hemangiopericytoma (HPC) is a rare brain tumor with aggressive biologic behavior associated with high recurrence rate and often with extracranial metastasis. The most common sites of extracranial metastasis of...
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Palliative Resection of Metastatic Brain Tumors Previously Treated by Stereotactic Radiosurgery

Jeon YS, Koh YC, Song SW, Cho J, Lim SD

BACKGROUND: Therapeutic approaches to brain metastases include surgery, whole-brain radiotherapy, stereotactic radiosurgery (SRS), and combination therapy. Recently, postoperative or preoperative SRS draws more attention to reduce postoperative recurrence in brain...
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Clinical Significance of Substaging and HER2 Expression in Papillary Nonmuscle Invasive Urothelial Cancers of the Urinary Bladder

Lim SD, Cho YM, Choi GS, Park HK, Paick SH, Kim WY, Kim SN, Yoon G

The study aimed to verify the prognostic utility, therapeutic application and clinical benefits of tumor substaging and HER2 status in papillary non-muscle invasive bladder cancer (NMIBC). Select NMIBC transurethral resection...
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Expression of Peroxisome Proliferato Activated Receptor gamma in Prostatic Adenocarcinoma

Park HK, Kim H, Kim HG, Cho YM, Jung WY, Han HS, Hwang TS, Kwon GY, Lim SD

Peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor has been investigated as the target for cancer treatment as well as metabolic disorders. Recent studies have demonstrated that PPAR-gamma ligands...
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Charcoal-Induced Granuloma That Mimicked a Nodal Metastasis on Ultrasonography and FDG-PET/CT after Neck Dissection

Choi JW, Moon WJ, Choi N, Roh HG, Kim MY, Kim NR, Moon SG, Chung HW, Lim SD, Yang JH

Charcoal can be used for preoperative localization of metastatic lymph nodes in the neck. Charcoal remains stable without causing foreign body reactions during as hort period. However, foreign body reactions...
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The Relevance between Renal Ultrasonographic Findings and Disease Course in Two Poststreptococcal Glomerulonephritis (PSGN) Patients

Lee JH, An YK, Yoo HY, Kwak BO, Park HW, Lim SD, Son JS, Chung SC, Kim KS

Poststreptococcal glomerulonephritis (PSGN) is one of the most well-known and important infectious renal diseases resulting from a prior infection with group A beta-hemolytic streptococcus. The typical clinical characteristics of the...
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Imaging Mass Spectrometry in Papillary Thyroid Carcinoma for the Identification and Validation of Biomarker Proteins

Min KW, Bang JY, Kim KP, Kim WS, Lee SH, Shanta SR, Lee JH, Hong JH, Lim SD, Yoo YB, Na CH

Direct tissue imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization and time-of-flight (MALDI-TOF) mass spectrometry has become increasingly important in biology and medicine, because this technology can detect the...
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A Case of "Full-house" Nephropathy in a Non-lupus Patient

Yoo HY, Son M, Cho MH, Kwak BO, Park HW, Lim SD, Chung S, Kim KS

Histopathologic evidence of "full-house" immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He...
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Rhabdoid Colorectal Carcinomas: Reports of Two Cases

Lee SH, Seol H, Kim WY, Lim SD, Kim WS, Hwang TS, Han HS

  • KMID: 2277414
  • Korean J Pathol.
  • 2013 Aug;47(4):372-377.
Rhabdoid colorectal carcinomas are very rare and only 10 cases have been previously reported. We report two cases of rhabdoid colorectal carcinoma, one arising in the sigmoid colon of a...
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ERG Immunohistochemistry as an Endothelial Marker for Assessing Lymphovascular Invasion

Kim S, Park HK, Jung HY, Lee SY, Min KW, Kim WY, Han HS, Kim WS, Hwang TS, Lim SD

  • KMID: 2277412
  • Korean J Pathol.
  • 2013 Aug;47(4):355-364.
BACKGROUND: ERG, a member of the ETS family of transcription factors, is a highly specific endothelial marker. We investigated whether the use of ERG immunostaining can help pathologists detect lymphovascular...
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A Case of Multifocal Papillary Thyroid Carcinoma Consisting of One Encapsulated Follicular Variant with BRAF K601E Mutation and Three Conventional Types with BRAF V600E Mutation

Kim WY, Ko YS, Hwang TS, Han HS, Lim SD, Kim WS, Oh SY

  • KMID: 2277449
  • Korean J Pathol.
  • 2013 Jun;47(3):293-298.
Multifocal papillary thyroid carcinoma (mPTC) comprises about 20-30% of PTC. In mPTC, individual tumor foci can be identical or frequently composed of different histological types including follicular, solid, tall-cell or...
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Association of acute tubular necrosis with gross hematuria in cirrhosis-related immunoglobulin A nephropathy

Han JS, Lim SD, Choi WH, Hong SC, Park JH, Park E, Hong MJ, Lee CI, Park JH, Lee JH, Song JO, Jo YI

  • KMID: 2224320
  • Kidney Res Clin Pract.
  • 2013 Mar;32(1):43-46.
Immunoglobulin A (IgA) nephropathy associated with cirrhosis is the most common form of secondary IgA nephropathy (IgAN). Cirrhosis-related IgAN is usually clinically silent with a rare occurrence of gross hematuria,...
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