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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of...
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High-dose versus Low-dose 5-Fluorouracil and Cisplatin Based Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma

Lim CJ, Hong JY, Ko YS, Chung MW, Jun CH, Choi SK, Cho SB

BACKGROUND/AIMS: Hepatic arterial infusion chemotherapy (HAIC) has been reported as an effective treatment for advanced hepatocellular carcinoma. The aim of this study is to compare the effect and safety between...
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Acute Pulmonary Infarction Complicated with Thromboembolism as the First Manifestation of Hepatocellular Carcinoma

Lim CJ, Hong JY, Jun CH, Choi SK, Cho SB

Acute pulmonary infarction by tumoral thromboemboli is an extremely rare fatal complication as the first clinical manifestation of hepatocellular carcinoma (HCC) patient with tumoral thrombi in the inferior vena cava....
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Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis

Lim CJ, Lee YM, Kang SG, Lim HW, Shin KO, Jeong SK, Huh YH, Choi S, Kor M, Seo HS, Park BD, Park K, Ahn JK, Uchida Y, Park K

Ultraviolet (UV) irradiation is a relevant environment factor to induce cellular senescence and photoaging. Both autophagy- and silent information regulator T1 (SIRT1)-dependent pathways are critical cellular processes of not only...
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Ellagic acid plays a protective role against UV-B-induced oxidative stress by up-regulating antioxidant components in human dermal fibroblasts

Baek B, Lee SH, Kim K, Lim HW, Lim CJ

Ellagic acid (EA), an antioxidant polyphenolic constituent of plant origin, has been reported to possess diverse pharmacological properties, including anti-inflammatory, anti-tumor and immunomodulatory activities. This work aimed to clarify the...
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Complete Response of Single Nodular Large Hepatocellular Carcinoma with Pulmonary Metastasis by Sequential Transarterial Chemoembolization and Sorafenib: A Case Report

Kim GH, Yu HM, Lim CJ, Cho SB

Current guidelines recommend sorafenib as the first-line molecular target agent for advanced hepatocellular carcinoma (HCC) with extrahepatic metastasis and unresectable HCC. Sorafenib was reported to show survival benefit for patients...
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Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues

Choi SH, Moon JS, Jeon BS, Jeon YJ, Yoon BI, Lim CJ

BP201, porcine lung tissue-derived phospholipids, consists of phosphatidylcholine as a major phospholipid species. BP201 promoted hair growth after application onto the shaved backs of BALB/c and C3H mice. Its effect...
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Anti-Inflammatory, Antioxidant, Anti-Angiogenic and Skin Whitening Activities of Phryma leptostachya var. asiatica Hara Extract

Jung HJ, Cho YW, Lim HW, Choi H, Ji DJ, Lim CJ

  • KMID: 2170689
  • Biomol Ther.
  • 2013 Jan;21(1):72-78.
This work aimed to assess some pharmacological activities of P. leptostachya var. asiatica Hara. The dried roots of P. leptostachya var. asiatica Hara were extracted with 70% ethanol to generate...
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Monitoring of antibiotic resistance in bacteria isolated from laboratory animals

Goo JS, Jang MK, Shim SB, Jee SW, Lee SH, Bae CJ, Park S, Kim KJ, Kim JE, Hwang IS, Lee HR, Choi SI, Lee YJ, Lim CJ, Hwang DY

The drug resistance of microorganisms isolated from laboratory animals never treated with antibiotics is being reported consistently, while the number of laboratory animals used in medicine, pharmacy, veterinary medicine, agriculture,...
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The Survey of Prevalence of Osteoporosis in Alzheimer's Disease Patients

Kim Y, Ahn KY, Yoon TH, Lim CJ, Shin WJ

  • KMID: 2255861
  • Korean J Bone Metab.
  • 2011 Nov;18(2):125-130.
OBJECTIVES: To evaluate the prevalence of osteoporosis in the Alzheimer's disease patients. METHODS: One hundred and twenty eight patients with Alzheimer's disease were included in this study. The patients are diagnosed...
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Investigation of the Bovine Leukemia Virus Proviral DNA in Human Leukemias and Lung cancers in Korea

Lee J, Kim Y, Kang CS, Cho DH, Shin DH, Yum YN, Oh JH, Kim SH, Hwang MS, Lim CJ, Yang KH, Han K

The bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. This study investigated the presence of the BLV in leukemia (179 acute lymphoblastic leukemia, 292 acute myeloid...
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Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells

Lim HW, Hong S, Jin W, Lim S, Kim SJ, Kang HJ, Park EH, Ahn K, Lim CJ

  • KMID: 1089461
  • Exp Mol Med.
  • 2005 Oct;37(5):497-506.
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in...
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Differential Thioredoxin Reductase Activity from Human Normal Hepatic and Hepatoma Cell Lines

Jung HI, Lim HW, Kim BC, Park EH, Lim CJ

  • KMID: 2428322
  • Yonsei Med J.
  • 2004 Apr;45(2):263-272.
Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins...
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Clinical Application of Polymerase Chain Reaction for Diagnosis of Pulmonary Tuberculosis in Pneumoconiotic Patient

Park JH, Lim CJ, Lee KH

  • KMID: 2027999
  • Korean J Occup Environ Med.
  • 1998 Feb;10(1):20-28.
Recent development in thepolymerase chain reaction (PCR) has brought an extraordinary opportunity for the rapid detection of M. tuberculosis in clinical specimens for the diagnosis of tuberculosis. Pneumoconiosis is a...
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Reconstruction combined with HBO therapy and iliac bone graft in mandibular fracture site osteomyelitis

Kim SN, Lee DK, Lim CJ, Yun SP

  • KMID: 1690149
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 1991 Mar;13(1):110-116.
No abstract available.
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A Radiological Study of the Elbow in Professional Baseball Players

Rowe SM, Kim SC, Lim CJ

Bony changes about the elbow in the baseball players are common problem. Pure bony injuries occur in the elbow of the throwing arm, but most often they have some associated...
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A case report of Angle's Class III subdivision

Kim JK, Lim CJ, Yang WS, Cho HW

  • KMID: 1675720
  • Korean J Orthod.
  • 1970 Dec;1(1):43-46.
No abstract available.
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A case report of Angle's Class II, division 1, subdivision

Lim CJ, Kim JK, Yang WS, Cho HW

  • KMID: 1675719
  • Korean J Orthod.
  • 1970 Dec;1(1):38-42.
No abstract available.
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Clinical Study on Recurrent Dislocation of the Shoulder: Treated with Putti-Platt Operation

Kim NH, Cho JH, Lim CJ

The clinical study on recurrent dislocation of the shoulder was performed on fourteen cases who were treated by Putti-Platt operation from July 1967 to November 1968. The cases studied were...
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Femoral Shaft Fractures in Adult (Clinical analysis of 73 cases)

Kee WS, Lim CJ

Clinical analysis of fracture of femral shaft in 73 cases treated at the 17 Army Hospital during the period from May 1965 to July 1968 is presented. 1) All the...
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