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KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure

Lee JH, Seo HW, Ryu JY, Lim CJ, Yi KY, Oh KS, Lee BH

G protein-coupled receptor kinase 5 (GRK5) has been considered as a potential target for the treatment of heart failure as it has been reported to be an important regulator of...
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Hematopoietic Stem Cell Registry Report: 2018

Kang ES, Lim CS, Han KS, Kim DW

Background: Hematopoietic stem cell (HSC) transplantation is an important therapeutic option for many malignant and non-malignant diseases. The whole transplant process involves multiple areas and complex steps. The laboratory procedures...
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Seroprevalence of Anti-SARS-CoV-2 Antibodies among Outpatients in Southwestern Seoul, Korea

Noh JY, Seo YB, Yoon JG, Seong H, Hyun H, Lee J, Lee N, Jung S, Park MJ, Song W, Yoon J, Lim CS, Ryou J, Lee JY, Kim SS, Cheong HJ, Kim WJ, Yoon SY, Song JY

Serosurveillance studies reveal the actual disease burden and herd immunity level in the population. In Seoul, Korea, a cross-sectional investigation showed 0.07% anti-severe acute respiratory syndrome coronavirus-2 antibody seropositivity among...
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The quick sepsis-related organ failure score has limited value for predicting adverse outcomes in sepsis patients with liver cirrhosis

Son J, Choi S, Huh JW, Lim CM, Koh Y, Kim KM, Shim JH, Lim YS, Hong SB

Background/Aims: The quick Sepsis-related Organ Failure Assessment (qSOFA) is a newly developed risk stratification tool, which has been presented along with a new sepsis definition, to classify infected patients outside...
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Bleeding after Endoscopic Resection in Patients with End-Stage Renal Disease on Dialysis: A Multicenter Propensity Score-Matched Analysis

Yoo IK, Kim CG, Suh YJ, Oh Y, Baik GH, Kim SM, Kim YD, Lim CH, Jeon JW, Hong SJ, Bang BW, Kim JS, Chung JW

Background/Aims: Frequent bleeding after endoscopic resection (ER) has been reported in patients with end-stage renal disease (ESRD). We aimed to evaluate the association and clinical significance of bleeding with ER...
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The Implication of Cytogenetic Alterations in Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm Identified by Fluorescence In Situ Hybridization and Their Potential Diagnostic Utility

Lim CS, Im K, Lee DS, Kwon W, Kim JR, Han Y, Kim SW, Jang JY

Background/Aims: We investigated chromosomal aberrations in patients with pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasm (IPMN) by fluorescence in situ hybridization (FISH) to identify cytogenetic changes and molecular...
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Maternal and Perinatal Outcomes in Pregnancy by Chronic Kidney Disease Stage Based on Midterm Glomerular Filtration Rate

Lim Cm, Choi MJ, Jeon Hr, Jung Sy, Kim Sy

Objective: Chronic kidney disease (CKD) is a known risk factor of pregnancy that increases the rates of preterm birth, intrauterine growth restriction, and preeclampsia. And maternal CKD may worsen due...
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Reduced risk for chronic kidney disease after recovery from metabolic syndrome: A nationwide populationbased study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Han K, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: Metabolic syndrome (MetS) is linked to various chronic comorbidities, including chronic kidney disease (CKD). However, few large studies have addressed whether recovery from MetS is associated with reduction in...
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Subclinical Hypothyroidism Affects the Long-Term Outcomes of Patients Who Undergo Coronary Artery Bypass Grafting Surgery but Not Heart Valve Surgery

Kim H, Kong SH, Moon JH, Kim SY, Park KH, Kim JS, Choh JH, Park YJ, Lim C

Background: The aim of this study was to determine the associations between subclinical hypothyroidism (SCH) and long-term cardiovascular outcomes after coronary artery bypass grafting (CABG) or heart valve surgery (HVS). Methods:...
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Clinical Significance of a High SARS-CoV-2 Viral Load in the Saliva

Yoon JG, Yoon J, Song JY, Yoon SY, Lim CS, Seong H, Noh JY, Cheong HJ, Kim WJ

Background: Patients with coronavirus disease 2019 (COVID-19) can unknowingly spread the virus to several people during the early subclinical period. Methods: We evaluated the viral dynamics in various body fluid specimens,...
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Survey of Risk-Based Quality Management Status andEstablishment of Operational Model in Clinical Trials

Kim E, Lim C

Purpose: With the release of the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use E6 addendum, it is very important to establish risk-based quality management systems which...
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Outcomes and Patency of Complex Configurations of Composite Grafts Using Bilateral Internal Thoracic Arteries

Shih BCH, Chung S, Kim H, Chang HW, Kim DJ, Lim C, Park KH, Kim JS

Background: It is generally agreed that using a bilateral internal thoracic artery (BITA) composite graft improves long-term survival after coronary artery bypass grafting (CABG). Although the left internal thoracic artery...
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2019 Seoul Consensus on Esophageal Achalasia Guidelines

Jung HK, Hong SJ, Lee OY, Pandolfino J, Park H, Miwa H, Ghoshal UC, Mahadeva S, Oshima T, Chen M, Chua ASB, Cho YK, Lee TH, Min YW, Park CH, Kwon JG, Park MI, Jung K, Park JK, Jung KW, Lim HC, Jung DH, Kim DH, Lim CH, Moon HS, Park JH, Choi SC, Suzuki H, Patcharatrakul T, Wu JCY, Lee KJ, Tanaka S, Siah KTH, Park KS, Kim SE, The Korean Society of Neurogastroenterology and Motility

  • KMID: 2500676
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):180-203.
  • doi: 10.5056/jnm20014
Esophageal achalasia is a primary motility disorder characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Achalasia is a chronic disease that causes progressive irreversible loss of...
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Iatrogenic Opioid Withdrawal Syndrome in Critically Ill Patients: a Retrospective Cohort Study

Hyun Dg, Huh JW, Hong SB, Koh Y, Lim CM

Background: Opioid withdrawal syndrome (OWS) may occur following the reduction or discontinuation of opioid analgesics. In critically ill pediatric patients, OWS is a common and clinically significant condition. However, OWS...
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Evaluation of Diagnostic Performance of Three Real-Time PCR Assays for the Detection of Mycobacteria Species

Kim Sw, Park YH, Ko YJ, Kim YH, Kim CH, Lim CS

Background: The disease burden caused by Mycobacterium tuberculosis (MTB) complex continues to decrease in most countries. However, the diseases caused by the nontuberculous mycobacteria (NTM) become a public health problem....
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Effects of Dental Hygienists Job Stress on Somatization in an Area

Kim MJ, Kim HS, Lim CY

Background: This study aims to analyze the job stress of dental hygienists and the factors affecting somatization and to provide basic data for effectively managing job stress and somatization of...
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Functional Outcomes of Hip Arthroscopy for Pediatric and Adolescent Hip Disorders

Lim C, Cho TJ, Shin CH, Choi IH, Yoo WJ

BACKGROUND: There is a paucity of literature on the use of hip arthroscopy for pathologic conditions in skeletally immature patients. Thus, the indications and safety of the procedure are still...
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The Impact of an Attending Intensivist on the Clinical Outcomes of Patients Admitted to the Cardiac Surgical Intensive Care Unit after Coronary Artery Bypass Grafting

Kim DJ, Sohn B, Kim H, Chang HW, Lee JH, Kim JS, Lim C, Park KH

Background: We aimed to investigate the associations of critical care provided in a cardiac surgical intensive care unit (CSICU) staffed by an attending intensivist with improvements in intensive care unit...
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Primary leiomyosarcoma of the liver: Two new cases and a systematic review

Esposito F, Lim C, Baranes L, Salloum C, Feray C, Calderaro , Azoulay D

Primary hepatic leiomyosarcoma (PHL) is a rare malignant tumor, which originates from smooth muscles. Clinical presentation and imaging features are non-specific and can mimick the most frequent primary liver tumors...
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Operation and Management of Seoul Metropolitan City Community Treatment Center for Mild Condition COVID-19 Patients

Lee SY, Song KJ, Lim CS, Kim BG, Chai YJ, Lee JK, Kim SH, Lim HJ

Background: In response to the disaster of coronavirus disease 2019 (COVID-19) pandemic, Seoul Metropolitan Government (SMG) established a patient facility for mild condition patients other than hospital. This study was...
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