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Clinical Characteristics and Outcomes of COVID-19 Cohort Patients in Daegu Metropolitan City Outbreak in 2020

Kim SW, Kim SM, Kim YK, Kim Jy, Lee YM, Kim BO, Hwangbo S, Park T

Background: A coronavirus disease 2019 (COVID-19) outbreak started in February 2020 and was controlled at the end of March 2020 in Daegu, the epicenter of the coronavirus outbreak in Korea....
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Effect of corticosteroid therapy in the early phase of acute respiratory distress syndrome: a propensitymatched cohort study

Baek MS, Lee Y, Hong SB, Lim CM, Koh Y, Huh JW

Background/Aims: It is unclear whether corticosteroid use in patients with acute respiratory distress syndrome (ARDS) improves survival. This study aimed to investigate whether the administration of corticosteroids to patients in...
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Organizing an in-class hackathon to correct PDF-to-text conversion errors of Genomics & Informatics 1.0

Kim S, Kim R, Kim RG, Ko E, Kim HS, Shin J, Cho D, Jin Y, Bae S, Jo YW, Jeong SA, Kim Y, Ahn S, Jang B, Seong J, Lee Y, Seo SE, Kim Y, Kim HJ, Kim H, Sung HL, Lho H, Koo J, Chu J, Lim J, Kim Y, Lee K, Lim Y, Kim M, Hwang S, Han S, Bae S, Kim S, Yoo S, Seo Y, Shin Y, Kim Y, Ko YJ, Baek J, Hyun H, Choi H, Oh JH, Kim DY, Nam HJ, Park HS

This paper describes a community effort to improve earlier versions of the full-text corpus of Genomics & Informatics by semi-automatically detecting and correcting PDF-to-text conversion errors and optical character recognition...
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Clinical Characteristics and Mortality Predictors of COVID-19 Patients Hospitalized at Nationally-Designated Treatment Hospitals

Moon SS, Lee K, Park J, Yun S, Lee YS, Lee DS

Background: Coronavirus disease 2019 (COVID-19) was first reported in December 2019 in China, and then it has disseminated worldwide. In Korea, a religious group-related super-spreading event triggered a sudden outbreak...
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Cilostazol ameliorates diabetic nephropathy by inhibiting highglucose- induced apoptosis

Chian CW, Lee YS, Lee YJ, Chen YH, Wang CP, Lee WC, Lee HJ

Diabetic nephropathy (DN) is a hyperglycemia-induced progressivedevelopment of renal insufficiency. Excessive glucose can increase mitochondrialreactive oxygen species (ROS) and induce cell damage, causing mitochondrial dysfunction.Our previous study indicated that cilostazol...
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Lymphatic Vessels Mapping in the Lower Extremities of a Healthy Asian Population

Lee YH, Kim HK, You HJ, Kim DW

Purpose: Intraoperative indocyanine green (ICG) lymphography is an effective tool to obtain real-time video images of functioning lymph vessels in edematous limbs. However, it is difficult to identify the course...
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Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress

Kang JM, Lee HS, Kim J, Yang DH, Jeong HY, Lee YH, Kim DJ, Park SH, Sung M, Kim J, An HJ, Lee SH, Lee SY

Background: Oxidative stress induced by chronic hyperglycemia is recognized as a significant mechanistic contributor to the development of diabetic kidney disease (DKD). Nonphagocytic nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) is...
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A Complex Cortical Malformation Caused by a Mutation in the Tubulin-Encoding TUBB3 Gene

Lee YH, Park NH

Tubulinopathy commonly refers to complex congenital and non-progressive brain malformations caused by mutations in the tubulin genes. Among tubulin-encoding genes, TUBB3 has rarely been reported as a cause of complex...
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Potentially Avoidable Hospitalization among Long-Term Care Insurance Beneficiaries with Dementia

Kim JH, Lee Y

Background: This study investigated the differences in the risk of potentially avoidable hospitalization (PAH) among eligible long-term care insurance (LTCI) beneficiaries with dementia for LTCI services in Korea. Nested case-control...
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Reversible Cerebral Vasoconstriction Syndrome Presenting as Transient Vessel Wall Enhancement on Contrast-Enhanced Fluid-Attenuated Inversion Recovery Images: A Case Report and Literature Review

Heo SA, Kim ES, Lee Y

Reversible cerebral vasoconstriction syndrome (RCVS) is a clinical and radiological syndrome with primary features that include hyperacute onset of severe headache and segmental vasoconstriction of the cerebral arteries, which resolve...
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Myostatin Inhibitors: Panacea or Predicament for Musculoskeletal Disorders?

Suh J, Lee YS

Myostatin, also known as growth differentiation factor 8 (GDF8), is a transforming growth factor-β (TGF-β) family member that functions to limit skeletal muscle growth. Accordingly, loss-of-function mutations in myostatin result...
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vidence-Based Nursing Practice Guideline: Ostomy Care

Lee YJ, Park HS, Kim MK, Seo HW, Lee MJ, Won EA, Jo GN

Purpose: The aim of this study was to develop an evidence-based guideline for stoma management providing institutional policy, assessment, complications and follow-up care. Methods: The guideline adaptation manual consisting of...
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Effect of Age on Laparoscopic Surgery and Postoperative Chemotherapy in Elderly Patients With Colorectal Cancer

Kim HH, Ihn MH, Lee YH, Lee J, Yun S, Cho SW

Purpose: We aimed to evaluate the postoperative complications of laparoscopic colorectal cancer (CRC) surgery and the adverse events of postoperative chemotherapy in elderly patients compared to younger patients and to...
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Autoimmune encephalitis and epilepsy: evolving definition and clinical spectrum

Seo JH, Lee YJ, Lee KH, Gireesh E, Skinner H, Westerveld M

Advances in autoimmune encephalitis studies in the past 10 years have led to the identification of new syndromes and biomarkers that have transformed the diagnostic approach to the disorder. The...
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Omental Torsion and Infarction Secondary to Omental Hernia in the Right Inguinal Canal

Lee YH, Lim JH, Ha HK

Omental torsion secondary to inguinal hernia has rarely been reported as a cause of acute abdominalpain. However, in our case, omental infarction due to prolonged inguinal hernia-associatedomental torsion led to...
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Prognostic Factors of Patients with Postinfantile Epilepsy and Multiple Independent Spike Foci on Electroencephalography

Kong J, Lee YJ, Ko A, Kim YM, Yeon GM, Nam SO

Purpose: Multiple independent spike foci (MISF) have been reported to be associated with hypsarrhythmia and slow spikes and waves. However, some patients with MISF demonstrate a good prognosis, such as...
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Lung ultrasound for early diagnosis and severity assessment of pneumonia in patients with coronavirus disease 2019

Cho YJ, Song KH, Lee Y, Yoon JH, Park JY, Jung J, Lim SY, Lee H, Yoon HI, Park KU, Kim HB, Kim ES

Background/Aims: Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. We sought to determine the utility of lung ultrasound for early detection of pneumonia...
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Effectiveness of nivolumab versus regorafenib in hepatocellular carcinoma patients who failed sorafenib treatment

Lee CH, Lee YB, Kim MA, Jang H, Oh H, Kim SW, Cho EJ, Lee KH, Lee JH, Yu SJ, Yoon JH, Kim TY, Kim YJ

Background/Aims: Several treatment options are currently available for patients with hepatocellular carcinoma (HCC) failing previous sorafenib treatment. We aimed to compare the effectiveness of regorafenib and nivolumab in these patients. Methods:...
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Ramosetron versus Palonosetron in Combination with Aprepitant and Dexamethasone for the Control of Highly-Emetogenic Chemotherapy-Induced Nausea and Vomiting

Kang JH, Kwon JH, Lee YG, Park KU, An HJ, Sohn J, Seol YM, Lee H, Yun HJ, Ahn JS, Yang JH, Song H, Koo DH, Kim JY, Kim GM, Kim HJ

Purpose The purpose of this study was to compare ramosetron (RAM), aprepitant (APR), and dexamethasone (DEX) [RAD] with palonosetron (PAL), APR, and DEX [PAD] in controlling highly-emetogenic chemotherapy (HEC)–induced nausea and...
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Treatment Outcomes and Prognostic Factors of Acute Variceal Bleeding in Patients with Hepatocellular Carcinoma

Lee YR, Park SY, Tak WY

Background/Aims: The treatment outcomes and prognostic markers of acute variceal bleeding (AVB) in hepatocellular carcinoma (HCC) patients remain unclear. Therefore, we evaluated the clinical outcomes and prognostic factors of AVB...
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