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The First Korean Case of NUP98-NSD1 and a Novel SNRK-ETV6 Fusion in a Pediatric Therapy-related Acute Myeloid Leukemia Patient Detected by Targeted RNA Sequencing

Lim HJ, Lee JH, Lee YE, Baek HJ, Kook H, Park JH, Lee SY, Choi HW, Choi HJ, Kee SJ, Shin JH, Shin MG

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First Identification of IMP-1 Metallo-β-Lactamase in Delftia tsuruhatensis Strain CRS1243 Isolated From a Clinical Specimen

Cho SM, Hong SG, Lee Y, Song W, Yong D, Jeong SH, Lee K, Chong Y

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Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia

Park MS, Lee YE, Kim HR, Shin JH, Cho HW, Lee JH, Shin MG

Phospholipase C beta 2 (PLC-β2) regulates various essential functions in cell signaling, differentiation, growth, and mobility. We investigated the clinical implications of PLC-β2 protein expression in newly diagnosed normal karyotype...
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Clinical Application of Sequential Epigenetic Analysis for Diagnosis of Silver–Russell Syndrome

Kim SY, Shin CH, Lee YA, Shin CH, Yang SW, Cho TJ, Ko JM

Background: Silver-Russell syndrome (SRS) is a pre- or post-natal growth retardation disorder caused by (epi)genetic alterations. We evaluated the molecular basis and clinical value of sequential epigenetic analysis in pediatric...
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Standardization Status of Total Cholesterol Concentration Measurement: Analysis of Korean External Quality Assessment Data

Yoon YA, Lee YW, Kim S, Lee K, Park HD, Chun S, Min WK

Background: Total cholesterol concentration measurement is important in the diagnosis of dyslipidemia and evaluation of cardiovascular disease risk factors. Measurement reliability for obtaining an accurate total cholesterol concentration requires procedure...
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Diagnostic Efficacy of Serum Mac-2 Binding Protein Glycosylation Isomer and Other Markers for Liver Fibrosis in Non-Alcoholic Fatty Liver Diseases

Jang SY, Tak WY, Park SY, Kweon YO, Lee YR, Kim G, Hur K, Han MH, Lee WK

Background: Mac-2 binding protein glycosylation isomer (M2BPGi) has been established as a non-invasive biomarker for liver fibrosis. We evaluated the diagnostic efficacy of M2BPGi compared with those of other liver...
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Immunosuppressive Drug Measurement by Liquid Chromatography Coupled to Tandem Mass Spectrometry: Interlaboratory Comparison in the Korean Clinical Laboratories

Kim HK, Park HD, Lee SG, Chae H, Song SH, Lee YW, Yun YM, Ahn S, Kim S, Lee SM, Lee SY, Chun S, on behalf of the Clinical Mass Spectrometry Research Committee of the Korean Society of Clinical Chemistry

Background: Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is increasingly used for immunosuppressive drug tests. However, most LC-MS/MS tests are laboratory-developed and their agreement is unknown in different Korean...
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Efficacy of S-pantoprazole 10 mg in the Symptom Control of Non-erosive Reflux Disease: A Phase III Placebo-controlled Trial

Cho YK, Choi MG, Park H, Kim JW, Lee DH, Ko KH, Kim SG, Jung HY, Hong SJ, Lee YC, Lee SH

  • KMID: 2514680
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):223-230.
  • doi: 10.5056/jnm19053
Background/Aims S-isomer (S) pantoprazole is more bioavailable and less dependent on cytochrome 2C19 than is racemic pantoprazole. We aim to evaluate the efficacy and safety of 10 mg S-pantoprazole for treatment...
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A Systematic Review and Meta-analysis of Randomized Control Trials: Combination Treatment With Proton Pump Inhibitor Plus Prokinetic for Gastroesophageal Reflux Disease

Jung DH, Huh CW, Lee SK, Park JC, Shin SK, Lee YC

  • KMID: 2514673
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):165-175.
  • doi: 10.5056/jnm20161
Background/Aims Prokinetics can be used for treating patients with gastroesophageal reflux disease (GERD), who exhibit suboptimal response to proton pump inhibitor (PPI) treatment. We conducted a systematic review to assess the...
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Epidemiological Features and Economic Burden of Guillain-Barré Syndrome in South Korea: A Nationwide Population-Based Study

Kim AY, Lee H, Lee YM, Kang HY

Background and Purpose Guillain-Barré syndrome (GBS) is rare, but its symptoms are severe and they occasionally lead to long-term disability. Country-specific epidemiological evidence is useful for detecting potential problems at...
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The Gut Microbiome and Osteoarthritis: A Two-Sample Mendelian Randomization Study

Lee YH, Song GG

Objective: The aim of this study was to examine if the intestinal microbiome is causally correlated with osteoarthritis (OA) incidence. Methods: A two-sample Mendelian randomization (MR) study was conducted using...
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Health-related Quality of Life Outcomes of Adalimumab for Patients With Rheumatoid Arthritis in Korea

Lee Ms, Lee CH, Lee HS, Sung YK, Choi JR, Park K, Lim MK, Choi BY, Kim HA, Choi SW, Lee Y, Yoo WH

Objective: Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disorder that impairs patients’ overall health-related quality of life (HRQOL). In this study, we evaluated the effect of adalimumab in Korean...
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Hypertrichosis Lanuginosa Acquisita Associated with Autoimmune Hepatitis

Yim SH, Hong D, Jung KE, Seo YJ, Lee Y

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Analysis of the Conjunctival Microbiome in Patients with Atopic Keratoconjunctivitis and Healthy Individuals

Hur MS, Lee JS, Jang M, Shin HJ, Lee YW

Background: Atopic dermatitis (AD) has been clarified that imbalance of bacterial and fungal communities in the skin and gut play key roles in immunologic dysfunction. Atopic keratoconjunctivitis (AKC), one of...
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Predictor of Subungual Melanoma against Benign Longitudinal Melanonychia: A Retrospective Cohort Study from Korea

Yim SH, Kwon IS, Hong D, Jung KE, Lee Y, Seo YJ, Choi CW

Background: Longitudinal melanonychia (LM) is a common clinical finding. Most cases of LM are benign, and a waitand-see approach is preferred in the management of this condition. Nevertheless, it is...
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Association between BDNF Polymorphism and Depressive Symptoms in Patients Newly Diagnosed with Type 2 Diabetes Mellitus

Ryu JS, Lee YM, Kim YS, Kang S, Park JS, Ahn CW, Nam JS, Seok JH

Purpose: Little is known about the relationship between brain-derived neurotrophic factor (BDNF) gene polymorphisms and psychiatric symptoms in diabetes patients. We investigated the effects of BDNF Val/66/Met polymorphism, glucose status,...
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Association between stress and dietary habits, emotional eating behavior and insomnia of middle-aged men and women in Seoul and Gyeonggi

Choi O, Kim J, Lee Y, Lee Y, Song K

BACKGROUND/OBJECTIVES: The study was performed to investigate the degree of perceived stress by sex in middle-aged people, and to provide basic data for appropriate nutrition education and interventional measures for...
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Correction to: A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

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A Novel Method to Differentiate Tonsil-Derived Mesenchymal Stem Cells In Vitro into Estrogen-Secreting Cells

Kim HY, Lee Y, Yoon HS, Kim YH, Cho KA, Woo SY, Kim HS, Park BY, Jung SC, Jo I, Park WJ, Park JW, Ryu KH

BACKGROUND: The advantages of tonsil-derived mesenchymal stem cells (TMSCs) over other mesenchymal stem cells (MSCs) include higher proliferation rates, various differentiation potentials, efficient immune-modulating capacity, and ease of obtainment. Specifically,...
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Nationwide “Pediatric Nutrition Day” survey on the nutritional status of hospitalized children in South Korea

Lee YM, Ryoo E, Hong J, Kang B, Choe BH, Seo JH, Park JS, Jang HJ, Lee Y, Chang EJ, Chang JY, Lee HJ, Kim JY, Lee EH, Kim HJ, Chung JY, Choi YJ, Choi SY, Kim SC, Kang KS, Yi DY, Moon KR, Lee JH, Kim YJ, Yang HR

BACKGROUND/OBJECTIVES: To evaluate the nutritional status and prevalence of malnutrition in hospitalized children at admission and during hospitalization in South Korea. SUBJECTS/METHODS: This first cross-sectional nationwide “Pediatric Nutrition Day (pNday)” survey...
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