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Clinical Characteristics and Treatment Outcomes of De Novo Nonconvulsive Status Epilepticus: A Retrospective Study

Lee JJ, Park KI, Park JM, Kang K, Kwon O, Lee WW, Kim BK

Background and Purpose Nonconvulsive status epilepticus (NCSE) is challenging to diagnose. This study aimed to describe and classify the clinical features and electroencephalography (EEG) findings of patients with de novo...
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Human Cytomegalovirus (HCMV)-infected Astrocytoma Cells Impair the Function of HCMV-specific Cytotoxic T Cells

Kim J, Lee WW, Hwang ES

Background: Human cytomegalovirus (HCMV) infection in glioblastoma multiforme (GBM) is associated with a poor prognosis and may affect the pathogenesis of GBM. In this study, we investigated the role of...
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Dopa-responsive dystonia with additional unusual clinical features: A case report confirmed by molecular genetics

Lee WW, Choi JM, Lee CG

The term dopa-responsive dystonia (DRD) is used to describe a group of neurometabolic disorders, which are characterized by dystonia, and are typically associated with diurnal fluctuations and respond to levodopa...
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The Effect of Integrated Nursing using Cognicise and Neurofeedback

Weon HW, Heo GY, Kim JB, Shin JE, Lee WW, Son HK

Purpose: This study aimed to identify the effect of integrated nursing using cognicise and neurofeedback on cognition and ⍺ waves among elderly individuals. Methods: This quasi-experimental single group pretest-posttest study...
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Febrile Hashimoto’s encephalopathymimicking infectious encephalitis

Lee JJ, Youn MS, Park JM, Kwon O, Lee WW, Kang K, Kim BK

Hashimoto’s encephalopathy (HE) is a heterogeneous encephalopathy with diverse clinical presentations. Here we report on a 69-year-old woman who presented with confusion, aphasia, fever, and focal ictal discharges. Cerebrospinal fluid analysis and...
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Myocardial Positron Emission Tomography for Evaluation of Cardiac Sarcoidosis: Specialized Protocols for Better Diagnosis

Hwang IC, Bang JI, Yoon YE, Lee WW

Sarcoidosis is a multisystemic granulomatous disease of unknown etiology with various clinical presentations depending on the organs involved. Since cardiac sarcoidosis (CS) portends a higher risk of morbidity and mortality,...
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Characteristic Neuroimaging Findings in a Patient with Acute Metabolic Encephalopathy, Lactic Acidosis and Stroke-Like Episodes Syndrome Distinguishable from that of Acute Ischemic Stroke

Kim H, Lee Jj, Kim Bk, Kwon O, Park Jm, Kang K, Lee Ww

Metabolic encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome is characterized by encephalopathy mimicking acute stroke, which is rarely observed in adulthood. We present a case of a female who...
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Clinical Guidance for Point-of-Care Ultrasound in the Emergency and Critical Care Areas after Implementing Insurance Coverage in Korea

Choi WJ, Ha YR, Oh JH, Cho YS, Lee WW, Sohn YD, Cho GC, Koh CY, Do HH, Jeong WJ, Ryoo SM, Kwon JH, Kim HM, Kim SJ, Park CY, Lee JH, Lee JH, Lee DH, Park SY, Kang BS

Point-of-care ultrasound (POCUS) is a useful tool that is widely used in the emergency and intensive care areas. In Korea, insurance coverage of ultrasound examination has been gradually expanding in...
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Minimum Standardized Uptake Value from Quantitative Bone Single-Photon Emission Computed Tomography/Computed Tomography for Evaluation of Femoral Head Viability in Patients with Femoral Neck Fracture

Ryoo HG, Lee WW, Kim JY, Kong E, Choi WH, Yoon JK, K-SPECT Group

PURPOSE: Bone single-photon emission computed tomography/computed tomography (SPECT/CT) has been widely used for evaluation of femoral head viability in patients with femoral neck fracture. The current study aimed to investigate...
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Cohort Profile: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort in Korea

Shim JS, Song BM, Lee JH, Lee SW, Park JH, Choi DP, Lee MH, Ha KH, Kim DJ, Park S, Lee WW, Youm Y, Shin EC, Kim HC

Mortalities from cardiovascular disease in Korea have decreased markedly over the past three decades. The major cardiovascular and metabolic risk factors, however, remain prevalent, and their burden on health is...
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Recent Update of Advanced Imaging for Diagnosis of Cardiac Sarcoidosis: Based on the Findings of Cardiac Magnetic Resonance Imaging and Positron Emission Tomography

Chang S, Lee WW, Chun EJ

Sarcoidosis is a multisystem disease characterized by noncaseating granulomas. Cardiac involvement is known to have poor prognosis because it can manifest as a serious condition such as the conduction abnormality,...
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Clinical Applications of Technetium-99m Quantitative Single-Photon Emission Computed Tomography/Computed Tomography

Lee WW, K-SPECT Group

Single-photon emission computed tomography/computed tomography (SPECT/CT) is an already established nuclear imaging modality. Co-registration of functional information (SPECT) with anatomical images (CT) paved the way to the wider application of...
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Antitumor effect of TW-37, a BH3 mimetic in human oral cancer

Ahn CH, Lee WW, Jung YC, Shin JA, Hong KO, Choi S, Swarup N, Kim J, Ahn MH, Jung M, Cho SD, Jin B

TW-37 is a small molecule B cell lymphoma-2 (Bcl-2) homology 3 mimetic with potential anticancer activities. However, the in vivo anti-cancer effect of TW-37 in human oral cancer has not...
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Musculoskeletal Problems Affect the Quality of Life of Patients with Parkinson's Disease

Kim YE, Kim HJ, Yun JY, Lee WW, Yang HJ, Kim JM, Jeon B

OBJECTIVE: Musculoskeletal problems are more common in patients with Parkinson's disease (PD) than in normal elderly, but the impact of musculoskeletal problems on health-related quality of life (HRQoL) in patients...
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Expanding the Spectrum of Dopa-Responsive Dystonia (DRD) and Proposal for New Definition: DRD, DRD-plus, and DRD Look-alike

Lee WW, Jeon B, Kim R

Previously, we defined DRD as a syndrome of selective nigrostriatal dopamine deficiency caused by genetic defects in the dopamine synthetic pathway without nigral cell loss. DRD-plus also has the same...
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Heterogeneity Does Matter for Tumor Characterization

Lee WW

No abstract available.
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Utility of Quantitative Parameters from Single-Photon Emission Computed Tomography/Computed Tomography in Patients with Destructive Thyroiditis

Kim JY, Kim JH, Moon JH, Kim KM, Oh TJ, Lee DH, So Y, Lee WW

OBJECTIVE: Quantitative parameters from Tc-99m pertechnetate single-photon emission computed tomography/computed tomography (SPECT/CT) are emerging as novel diagnostic markers for functional thyroid diseases. We intended to assess the utility of SPECT/CT...
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Amantadine and the Risk of Dyskinesia in Patients with Early Parkinson's Disease: An Open-Label, Pragmatic Trial

Kim A, Kim YE, Yun JY, Kim HJ, Yang HJ, Lee WW, Shin CW, Park H, Jung YJ, Kim A, Kim Y, Jang M, Jeon B

OBJECTIVE: We examined whether amantadine can prevent the development of dyskinesia. METHODS: Patients with drug-naïve Parkinson's disease (PD), younger than 70 years of age and in the early stage of PD...
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Evaluation of Hot Nodules of Thyroid Gland Using Tc-99m Pertechnetate: a Novel Approach Using Quantitative Single-Photon Emission Computed Tomography/Computed Tomography

Lee R, So Y, Song YS, Lee WW

Planar scintigraphy using Tc-99mpertechnetate is useful for snapshot evaluation of hot thyroid nodules, which are pathologically follicular adenoma and seldom, if ever, malignant. The autonomy of the hot nodules has...
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Acute Temporary Autonomic Dysfunction Following Encephalitis

Yoon J, Kye MS, Lee WW, Kang K, Park JM, Kim BK, Kwon O, Lee JJ

No abstract available.
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