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Comparison of age‐dependent alterations in thioredoxin 2 and thioredoxin reductase 2 expressions in hippocampi between mice and rats

Yoo YH, Kim DW, Chen BH, Sim H, Kim B, Lee JC, Ahn JH, Park Y, Cho JH, Kang IJ, Won MH, Lee TK

Background Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a class...
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High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils

Seo WJ, Ahn JH, Lee TK, Kim B, Lee JC, Park JH, Yoo YH, Shin MC, Cho JH, Won MH, Park Y

Obesity has been known as an independent risk factor for stroke. Effects of high-fat diet (HFD)-induced obesity on neuronal damage in the somatosensory cortex of animal models of cerebral ischemia...
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Brain Factor-7® improves learning and memory deficits and attenuates ischemic brain damage by reduction of ROS generation in stroke in vivo and in vitro

Noh Y, Lee JW, Hong J, Kim SS, Ahn JH, Lee TK, Kim B, Won MH

Brain Factor-7® (BF-7), silk fibroin peptide, is known to be effective in improvement of memory and learning ability. In this study, the effects of BF-7 (10 mg/kg, p.o., pre-treatment for 7 days...
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Epileptic Vertigo and Nystagmus in Cerebral Hemiatrophy Syndrome

Lee ES, Kim KT, Lee TK, Moon HJ

No abstract available.
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Persistent Nystagmus in Chronic Phase of Lateral Medullary Infarction

Lee TK, Park JY, Kim H, Choi KD, Kim JS, Sung KB

Background and Purpose We aimed to determine the patterns and mechanisms of persistent nystagmus (PN) lasting >1 year in lateral medullary infarction (LMI). Methods We recruited 13 patients with PN due to LMI...
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RbAp48 expression and neuronal damage in the gerbil hippocampus following 5 min of transient ischemia

Park JH, Lee TK, Kim DW, Park CW, Park YE, Kim B, Lee JC, Lee HA, Won MH, Ahn JH

Histone-binding protein RbAp48 has been known to be involved in histone acetylation, and epigenetic alterations of histone modifications are closely associated with the pathogenesis of ischemic reperfusion injury. In the...
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Behçet's Disease with Deep Vaginal Ulcer Diagnosed for the First Time during Pregnancy

Lee EH, Lee TK, Lee J

Behçet's disease is a chronic multisystem inflammatory disease characterized by recurrent oral ulcer, genital ulcer and ocular inflammation. It affects mainly young adults ranging from twenties to forties, so the...
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Outcome of Schwannoma Resection at Upper Extremity with Preservation of Nerve Fascicle

Choi JH, Yang TY, Lee TK, Woo SH

PURPOSE: To analyze the risk factors and the rate of neurological complication occurring after micro-surgical enucleation of schwannoma, and the relationship between single fascicle resection and neurological deficiency. METHODS: From January...
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Predictors of Survival Rate in Fingertip Replantation

Lee TK, Choi JH, Yang TY, Woo SH

PURPOSE: To evaluate the variable factors affecting the survival rate in fingertip replantation. METHODS: We have performed 640 replantation cases of amputation distal to the distal interphalangeal joint between January 2010...
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Non-General Anesthesia for the Correction of Pediatric Trigger Thumbs

Yang TY, Lee TK, Choi JH, Woo SH

PURPOSE: To report the outcome of non-general anesthesia methods for correction of 185 pediatric trigger thumbs. METHODS: The corresponding author performed a total of 185 cases of pediatric trigger thumbs over...
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Age-dependent changes of p53 and p63 immunoreactivities in the mouse hippocampus

Lee TK, Park YE, Park CW, Kim B, Lee JC, Park JH, Lee HA, Won MH, Ahn JH

P53 and its family member p63 play important roles in cellular senescence and organismal aging. In this study, p53 and p63 immunoreactivity were examined in the hippocampus of young, adult...
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Functional Recovery of the Shoulder after Arthroscopic Treatment for Chronic Calcific Tendinitis

Lee TK, Shin SJ

BACKGROUND: We investigated the resolution of pain and functional recovery of shoulder after arthroscopic removal of calcific deposits in patients with chronic calcific tendinitis. METHODS: We enrolled 39 patients who were...
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The relationship between low survival and acute increase of tumor necrosis factor α expression in the lung in a rat model of asphyxial cardiac arrest

Park Y, Tae HJ, Cho JH, Kim IS, Ohk TG, Park CW, Moon JB, Shin MC, Lee TK, Lee JC, Park JH, Ahn JH, Kang SH, Won MH, Cho JH

Cardiac arrest (CA) is sudden loss of heart function and abrupt stop in effective blood flow to the body. The patients who initially achieve return of spontaneous circulation (RoSC) after...
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Interaction of Autonomic and Vestibular System

Lee ES, Lee TK

The relationship between the vestibular system and the autonomic nervous system has been well studied in the context of the maintenance of homeostasis to the changing internal and external milieus....
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Factors associated with hospitalization via emergency department in children with acute bronchiolitis

Lee TK, Kyong YY, Woo SH, Park JT, Oh YM, Jung HH, Choi SM

PURPOSE: In infants and young children, acute bronchiolitis is a leading cause of hospitalization via emergency departments (EDs). We aimed to investigate factors associated with hospitalization via ED in children...
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Glioneuronal Tumor with Neuropil-Like Islands in the Cerebellum: A Case Report

Lee YJ, Hwang YS, Chang ED, Lee TK, Kim YJ

Glioneuronal tumor with neuropil-like islands (GTNI) is a rare and novel mixed neuronal-glial tumor that typically affects the supratentorial cerebral hemispheres of adult patients. It is extremely rare for GTNIs...
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Changes in histopathology and tumor necrosis factor-α levels in the hearts of rats following asphyxial cardiac arrest

Lee JH, Lee TK, Kim IH, Lee JC, Won MH, Park JH, Ahn JH, Shin MC, Ohk TG, Moon JB, Cho JH, Park CW, Tae HJ

OBJECTIVE: Post cardiac arrest (CA) syndrome is associated with a low survival rate in patients who initially have return of spontaneous circulation (ROSC) after CA. The aim of this study...
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Nerve Repair and Nerve Grafting in Brachial Plexus Injuries

Lee TK, Yoon JO, Shin YH, Kim JK

Brachial plexus injuries (BPI) can have devastating effects on upper extremity function, however, treatment in this injuries remains a difficult problem. Several kinds of surgical methods have been used to...
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Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils

Ahn JH, Lee TK, Park JH, Cho JH, Kim IH, Lee JC, Hong S, Jeon YH, Kang IJ, Lee YJ, Won MH, Lee CH

Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus,...
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Reversible Lesion in The splenium of The Corpus Callosum Induced by Topiramate in a Patient with Migraine

Heo D, Lee SK, Park JH, Lee TK

Reversible lesion in the splenium of the corpus callosum in patients with epilepsy is often associated with some antiepileptic drugs. However, topiramate has never been reported as a possible inducer...
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