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Impact of gender on chronic obstructive pulmonary disease outcomes: a propensity scorematched analysis of a prospective cohort study

Cho J, Lee CH, Kim DK, Hwang HG, Kim YI, Choi HS, Park JW, Yoo KH, Jung KS, Lee SD

Background/Aims: Despite increasing awareness of the burden of chronic obstructive pulmonary disease (COPD) in women, knowledge regarding gender differences in COPD outcomes is limited. Therefore, we aimed to evaluate whether...
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Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning

Kim M, Lee SD, Kim MY

Acetaminophen or paracetamol (N-acetyl-para-aminophenol [APAP]) is a safe and effective antipyretic and analgesic drug and is a representative nonprescription drug. However, APAP is one of the most common nonprescription drugs...
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Risk Factors of Febrile Urinary Tract Infection after Ureteral Reimplantation in Infant

Lee S, Chung JM, Lee SD

Purpose: Children with febrile urinary tract infection (fUTI) and vesicoureteral reflux (VUR) show significant morbidity. Few studies have examined the incidence of fUTI after ureteral reimplantation for congenital urinary tract...
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Hyperuricemia Is Not Predictive of Long-Term Outcome in Patients with Stable Chronic Obstructive Pulmonary Disease

Hwang JJ, Oh YM, Rhee CK, Yoo KH, Park YB, Yoon HI, Lim SY, Lee JH, Kim EK, Kim TH, Lee SW, Lee SD, Lee JS, KOLD Group

BACKGROUND: Although the association of hyperuricemia with an increased risk of mortality has been demonstrated in the context of acute exacerbation of chronic obstructive pulmonary disease (COPD), the long-term outcomes...
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Epidemiology of Antiphospholipid Syndrome in Korea: a Nationwide Population-based Study

Hwang JJ, Shin SH, Kim YJ, Oh YM, Lee SD, Kim YH, Choi CW, Lee JS

BACKGROUND: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by arterial and venous thrombosis or pregnancy morbidity in patients with persistent antiphospholipid antibodies. However, nationwide population-based epidemiology studies regarding...
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Analysis of high predicted pulmonary function: possibility of overestimation in small elderly examinees

Chang Y, Kim HC, Jo KW, Lee JS, Oh YM, Lee SD, Lee SW

Background/Aims: Few studies have attempted to interpret unusually high predicted pulmonary function test results. This study aimed to investigate the demographic features of patients with an unusually high predicted pulmonary...
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Classification of Common Relationships Based on Short Tandem Repeat Profiles Using Data Mining

Jeong SJ, Lee HJ, Lee SD, Lee SH, Park SJ, Kim JS, Lee JW

We reviewed past studies on the identification of familial relationships using 22 short tandem repeat markers. As a result, we can obtain a high discrimination power and a relatively accurate...
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Clinical Utility of Quantitative CT Analysis for Fissure Completeness in Bronchoscopic Lung Volume Reduction: Comparison between CT and Chartisâ„¢

Lee SW, Shin SY, Park TS, Choi YY, Park JC, Park J, Oh SY, Kim N, Lee SH, Lee JS, Seo JB, Oh YM, Lee SD, Lee SM

OBJECTIVE: The absence of collateral ventilation (CV) is crucial for effective bronchoscopic lung volume reduction (BLVR) with an endobronchial valve. Here, we assessed whether CT can predict the Chartisâ„¢ results. MATERIALS...
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Clinical Phenotypes, Comorbidities, and Exacerbations according to Serum 25-OH Vitamin D and Plasma Fibrinogen Levels in Chronic Obstructive Pulmonary Disease

Hyun DG, Oh YM, Lee SW, Lee SD, Lee JS

BACKGROUND: Although vitamin D deficiency is prevalent in patients with chronic obstructive pulmonary disease (COPD), the influence of vitamin D deficiency on COPD has not been fully established. Moreover, the...
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Repeat hepatectomy for recurred colorectal liver metastasis: is it justified?

Park J, Lee SD, Han SS, Kim SH, Park SJ, Oh JH, Joo J

PURPOSE: Liver resection is considered the only curative treatment modality for colorectal liver metastasis. The recurrence rate after hepatectomy is >50%. Two or more hepatectomies are applied to treat recurred...
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Utility of Computed Tomography in a Differential Diagnosis for the Patients with an Initial Diagnosis of Chronic Obstructive Pulmonary Disease Exacerbation

Park HJ, Kim SH, Kim HC, Lee BY, Lee SW, Lee JS, Lee SD, Seo JB, Oh YM

BACKGROUND: The utility of computed tomography (CT) in the differential diagnosis of patients with chronic obstructive pulmonary disease (COPD) exacerbation remains uncertain. However, due to the low cost associated with...
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Rivaroxaban versus Low-Molecular-Weight Heparin for Venous Thromboembolism in Gastrointestinal and Pancreatobiliary Cancer

Lee JH, Oh YM, Lee SD, Lee JS

BACKGROUND: Low-molecular-weight heparin (LMWH) is the standard treatment for venous thromboembolism (VTE) in patients with active cancer. However, use of factor Xa inhibitors, such as rivaroxaban, is increasing on the...
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Single Nucleotide Polymorphisms Associated with Alcohol-Induced Flushing Syndrome in Korean Population

Lee JH, Seo HJ, Cho S, Kim MY, Lee SD

Alcohol-induced flushing syndrome is one of the alcohol hypersensitivity reactions commonly found among Asian population. This study was designed to find markers that can predict this particular propensity among Korean...
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Bronchial Thermoplasty in Patients with Severe Uncontrolled Asthma: First Korean Cases

Kang J, Cho YS, Choi DK, Lee JS, Oh YM, Lee SD, Lee SW

Bronchial thermoplasty is a nonpharmacological treatment for severe asthma that delivers thermal energy to the bronchial walls and reduces hypertrophied smooth muscle mass. Previous studies have shown its efficacy and...
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Microbiology of smegma: Prospective comparative control study

Chung JM, Park CS, Lee SD

PURPOSE: The aim of the study was to investigate the common bacteria found in the smegma in the subpreputial space of asymptomatic boys prospectively, and to determine the difference of...
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Analysis of State-Trait Anxiety Inventory for Patients Diagnosed with Insomnia in an Outpatient Department

Lee SD, Ryu SH, Ha JH, Jeon HJ, Park DH

OBJECTIVES: Insomnia patients who visited the psychiatric outpatient of a university department, were divided into those patients with insomnia alone and those with depression or anxiety disorder, along with insomnia....
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A Study on the Efficacy and Safety of Rivaroxaban in Urologic Cancer-Associated Venous Thromboembolism

Lee JH, You D, Lee SD, Oh YM, Lee JS

PURPOSE: Although direct oral anticoagulants (DOACs) are recommended as an alternative to low-molecular weighted heparin for cancer-associated venous thromboembolism (VTE), there is no firm evidence on the efficacy and safety...
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Prevalence of Emotional Distress and Related Factors of Orthopedic Surgical Patients in a Military Hospital : A Cross-sectional Feasibility Study

Oh IM, Hong M, Lee SY, Yoon GH, Lee H, Kim MJ, Kim HM, Lee SD

OBJECTIVE: The purpose of this study was to investigate prevalence of psychiatric symptoms and determine predictors of emotional distress of military hospital surgical patients. METHODS: This study examined 104 orthopedic patients...
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Pharmacological evaluation of HM41322, a novel SGLT1/2 dual inhibitor, in vitro and in vivo

Lee KH, Lee SD, Kim N, Suh KH, Kim YH, Sim SS

HM41322 is a novel oral sodium-glucose cotransporter (SGLT) 1/2 dual inhibitor. In this study, the in vitro and in vivo pharmacokinetic and pharmacologic profiles of HM41322 were compared to those...
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Clinical Phenotype of a First Unprovoked Acute Pulmonary Embolism Associated with Antiphospholipid Antibody Syndrome

Na YS, Jang S, Hong S, Oh YM, Lee SD, Lee JS

BACKGROUND: Antiphospholipid antibody syndrome (APS), an important cause of acquired thrombophilia, is diagnosed when vascular thrombosis or pregnancy morbidity occurs with persistently positive antiphospholipid antibodies (aPL). APS is a risk...
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