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Introduction to the human disease resource search and distribution platform through the Korea Biobank Network portal

Kim YH, Cha HR, Lee JE, Cha SE, Choi YJ

Human-derived materials are a crucial element of research in the life sciences. The Korea Biobank Network (KBN) portal is a shared open platform that provides the nationʼs most extensive disease...
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The Importance of Early Recognition, Timely Management, and the Role of Healthcare Providers in Multisystem Inflammatory Syndrome in Children

Lee JH, Han HS, Lee JK

In April 2020, a pediatric report of an unusual inflammatory illness associated with coronavirus disease 2019 (COVID-19) led to similar cases in Europe and North America, which was referred to...
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Impact of Cardiovascular Risk Factors and Cardiovascular Diseases on Outcomes in Patients Hospitalized with COVID-19 in Daegu Metropolitan City

Park BE, Lee JH, Park HK, Kim HN, Jang SY, Bae MH, Yang DH, Park HS, Cho Y, Lee BY, Nam CW, Lee JB, Kim U, Chae SC, the Daegu COVID-19 Research Project

Background: Data regarding the association between preexisting cardiovascular risk factors (CVRFs) and cardiovascular diseases (CVDs) and the outcomes of patients requiring hospitalization for coronavirus disease 2019 (COVID-19) are limited. Therefore,...
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Comparative Survival Outcome of Robot-Assisted Staging Surgery Using Three Robotic Arms versus Open Surgery for Endometrial Cancer

Eoh KJ, Lee DW, Lee JH, Nam EJ, Kim SW, Kim YT

Purpose: There is lack of data on direct comparison of survival outcomes between open surgery and robot-assisted staging surgery (RSS) using three robotic arms for endometrial cancer. The purpose of...
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Sarcopenia as a Predictor of Prognosis in Early Stage Ovarian Cancer

Chae SH, Lee C, Yoon SH, Shim SH, Lee SJ, Kim SN, Chung S, Lee JY

Background: To identify sarcopenia as a predictive prognostic factor of ovarian cancer in terms of survival outcome in patients with early-stage ovarian cancer. Methods: Data of Konkuk University Medical Center from...
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Trends in End-of-Life Resource Utilization and Costs among Prostate Cancer Patients from 2006 to 2015: A Nationwide Population-Based Study

Ha YS, Kim SY, Chung JI, Choi H, Kim JH, Yu HS, Cho IC, Kim HJ, Chung HC, Koh JS, Lee JY, Park DJ, Kim HT, Yoo ES, Kwon TG, Min K, Kim WJ, Yun SJ, Park JH

Purpose:The purpose of this study was to evaluate end-of-life resource utilization and costs for prostate cancer patients during the last year of life in Korea. Materials and Methods:The study used the...
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Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study

Kim SJ, Park MI, Kim GH, Lee MW, Jung K, Lee J, Seol SY, Jee SR, Lee HS, Jang JS, Cha JH, Busan, Ulsan, Gyeongnam Society of Neurogastroenterology and Motility

  • KMID: 2510064
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):71-77.
  • doi: 10.5056/jnm20069
Background/Aims The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking....
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Maintenance chemotherapy after 6 cycles of platinum-doublet regimen in anthracycline-and taxane-pretreated metastatic breast cancer

Joung EK, Yang JH, Oh S, Park SJ, Lee J

Background/Aims Sequential monotherapy is recommended for anthracycline-and taxane-resistant metastatic breast cancer (MBC), but combination chemotherapy is considered in patients with visceral crisis. Cisplatin-doublet chemotherapy is a combination regimen for MBC, but...
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Magnesium Hydride Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia

Lee MJ, Lee JH, Kim DK, Lee NS, Jeong YG, Jeong JH, Park JH, Yoo YC, Han SY

Abstract : Reactive oxygen species (ROS)-mediated oxidative stress plays a key role in the pathogenesis of central nervous system diseases, including vascular dementia (VaD). Thus, scientific attention has been given...
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Impact of extended-criteria donor lungs according to preoperative recipient status and age in lung transplantation

Suh JW, Lee JG, Park MS, Kim SY, Jeong SJ, Paik HC

Background: Organ donor shortage remains as one of the limiting factors for lung transplantation. Given the increase in waiting time, preoperative condition has worsened and affects surgical outcomes. This study...
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Out-of-Hospital Data: Patient Generated Health Data

Lee J, Kim HS, Kim J

Patient-generated health data (PGHD) are health-related data generated, recorded, and collected by patients or caregivers. Its main advantage is that patients can actively participate in their own health care, since...
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Comparison of Preanalytical Sample Stability between Serum and Ethylenediaminetetraacetic Acid Plasma for the Measurement of Biological Analytes

Lee J, Jeon K, Lee T, Lee J, Kim M, Kim HS, Lee YK, Kang HJ

Background: In this study, we aim to examine the effects of pre-analytical factors such as specimen type (serum or plasma), collection and storage conditions, and time, on the results of...
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Positional Audiometry in Patients with Light Cupula: A Preliminary Study

Lee J, Lee DH, Shin JE, Kim CH

Objectives: Light cupula is characterized by persistent geotropic direction-changing positional nystagmus in a supine head-roll test. The purpose of this study is to investigate if hearing level is influenced by...
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Effect of Korean Red Ginseng on Early Vestibular Function Restoration after Unilateral Labyrinthectomy

Lee J, Kim MJ, Han GC

Objectives: Vertigo is a common condition. Definitive treatment is to induce vestibular compensation. Currently, no medications have been discovered that enhance vestibular functional restoration. The current study was conducted to...
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Air and Environmental Contamination Caused by COVID-19 Patients: a MultiCenter Study

Kim UJ, Lee SY, Lee JY, Lee A, Kim SE, Choi OJ, Lee JS, Kee SJ, Jang HC

Background: The purpose of this study was to determine the extent of air and surface contamination of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in four health care facilities with hospitalized...
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Impacts of Remaining Single above the Mean Marriage Age on Mental Disorders and Suicidality: a Nationwide Study in Korea

Lee J, Kim H, Woo J, Chang SM, Hong JP, Lee DW, Hahm BJ, Cho SJ, Park JI, Jeon HJ, Seong SJ, Park JE, Kim BS

Background: This study investigated the impact of getting older than the mean marriage age on mental disorders and suicidality among never-married people. Methods: We performed an epidemiological survey, a nationwide study...
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Comparison between minimally invasive plate osteosynthesis and the deltopectoral approach with allogenous fibular bone graft in proximal humeral fractures

Kim JY, Lee J, Kim SH

Background: Both allogenous fibular bone graft and minimally invasive plate osteosynthesis have been developed to reduce issues such as fixation failure, displacement, angulation, and nonunion after plate fixation of proximal...
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The health-related quality-of-life of chronic obstructive pulmonary disease patients and disease-related indirect burdens

Choi HS, Yang DW, Rhee CK, Yoon HK, Lee JH, Lim SY, Kim YI, Yoo KH, Hwang YI, Lee SH, Park YB

Background/Aims: Many chronic obstructive pulmonary disease (COPD) patients have physical limitations. We investigated EuroQol five-dimensions five-level (EQ-5D-5L) of COPD patients to assess quality of life, and assessed indirect burden including time...
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Induced Pluripotent Stem Cell Modeling of Best Disease and Autosomal Recessive estrophinopathy

Lee JH, Oh Jo, Lee CS

Purpose: To understand the pathophysiology of Best disease (BD) and autosomal recessive bestrophinopathy (ARB) by establishing an in vitro model using human induced pluripotent stem cell (iPSC). Materials and Methods:...
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All-Trans Retinoic Acid Synergizes with Enasidenib to Induce Differentiation of IDH2-Mutant Acute Myeloid Leukemia Cells

Kim Y, Jeung HK, Cheong JW, Song J, Bae SH, Lee JI, Min YH

Purpose: Pharmacological inhibition of mutant isocitrate dehydrogenase (IDH) reduces R-2-hydroxyglutarate (2-HG) levels and restores cellular differentiation in vivo and in vitro. The IDH2 inhibitor enasidenib (AG-221) has been approved by...
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