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Acute Hydronephrosis owing to A Giant Fecaloma in an Older Patient

Joo N, Lee HS

Hydroureteronephrosis with acute urinary tract obstruction can lead to serious complications such as obstructive nephropathy or pyelonephritis. We report the first case of hydroureteronephrosis caused by a giant fecaloma in...
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Beneficial Effect of Chloroquine and Amodiaquine on Type 1 Diabetic Tubulopathy by Attenuating Mitochondrial Nox4 and Endoplasmic Reticulum Stress

Kang JM, Lee HS, Kim J, Yang DH, Jeong HY, Lee YH, Kim DJ, Park SH, Sung M, Kim J, An HJ, Lee SH, Lee SY

Background: Oxidative stress induced by chronic hyperglycemia is recognized as a significant mechanistic contributor to the development of diabetic kidney disease (DKD). Nonphagocytic nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) is...
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Prediction of TP53 mutations by p53 immunohistochemistry and their prognostic significance in gastric cancer

Hwang HJ, Nam SK, Park H, Park Y, Koh J, Na HY, Kwak Y, Kim WH, Lee HS

Background: Recently, molecular classifications of gastric cancer (GC) have been proposed that include TP53 mutations and their functional activity. We aimed to demonstrate the correlation between p53 immunohistochemistry (IHC) and...
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A Case of Preleukemic Chronic Myeloid Leukemia Following Chemotherapy and Autologous Transplantation for T-lymphoblastic Lymphoma

Choi H, Cho Sr, Yang D, Lee W, Hwang H, Lee HS, Kim DJ, Kim T, Kim MH

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Repurposing Auranofin, an Anti-Rheumatic Gold Compound, to Treat Acne Vulgaris by Targeting the NLRP3 Inflammasome

Yang G, Lee SJ, Kang HC, Cho YY, Lee HS, Zouboulis CC, Han SH, Ma KH, Jang JK, Lee JY

Activation of the NLRP3 inflammasome is critical for host defense as well as the progression of inflammatory diseases through the production of the proinflammatory cytokine IL-1β, which is cleaved by...
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The impact of emergency department expansion on crowding and patient flow

Yoon H, Lee HS, Park JM, Kim JH, Lee JH, Park IC, Chung SP, Kim MJ

  • KMID: 2506068
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):420-429.
Objective: Overcrowding in the emergency department (ED) has been a long-standing global problem, but has yet to be resolved. This study was undertaken to investigate whether expansion of the ED...
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May–Thurner Syndrome with Deep Vein Trombosis after Total Knee Arthroplasty

Lee HS, Kim YW, Jung SH, Lee SW

May–Thurner syndrome (MTS), also known as iliac vein compression syndrome, is a condition, in which compression of the commonvenous outflow tract of the left lower extremity can cause discomfort, swelling,...
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Study of Functional Appliance for Treatments of Children and Adolescents with Class II Malocclusion

Kang H, Lee K, Kim M, Nam O, Lee Hs, Kim K, Choi S

The purpose of this study was to evaluate the skeletal and dentoalveolar effects and optimal timing for treatment of class II malocclusion with functional appliances in children and adolescents. A...
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Treatment of peripheral neuropathy: a multidisciplinary approach is necessary

Lee HS

The number of patients with peripheral neuropathy or neuropathic pain is increasing. The recommended treatment for peripheral neuropathy and neuropathic pain is proper medications, exercise, physical therapy, and support. Overly...
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Association between Body Weight Perception and Metabolic Syndrome in Korean Adults: The Korea National Health and Nutrition Examination Survey 2015–2016

Kim LY, Shim KW, Lee HS, Lee SW, Choi JY

Background: Obesity has become a concern globally. The incidence of metabolic syndrome has increased rapidly in Korea over the past decades.Previous studies have reported obesity as a major cause of...
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Introduction of Community-Based Preconception Care for Men and Women of Childbearing Age in Seoul

Na BJ, Lee MJ, Lee HS, Min SK, Kim HO, Ahn KH, Lee WR, Sohn IS, Ha EH, Joo SH, Kim HS, Kim YA, Han JY

Community-based preconception care for men and women of childbearing age has been introduced in Seoul. The program aims to focus on problem areas such as low birth rate, fertility issues...
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Genetic Signatures of Acute Asthma Exacerbation Related With Ineffective Response to Corticosteroid

Kang MG, Lee HS, Tantisira , Park HW

Purpose: Acute exacerbation (AE) is an important domain of asthma management and may be related with ineffective response to corticosteroid. This study aimed to find mechanisms of AE using genome-wide...
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Endoscopic and Endosonographic Features of Histologically Proven Gastric Ectopic Pancreas by Endoscopic Resection

Lee HS, Kim DH, Park SY, Kim S, Kim GT, Cho E, Yoon JH, Park CH, Kim HS, Choi SK, Kim NI, Rew JS

Background/Aims: Distinguishing gastric ectopic pancreas (GEP) from malignant tumors is relatively difficult. This study evaluated the endosonography findings of pathologically proven GEP. Methods: Thirty-one patients diagnosed with GEP based on a...
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Minimally Invasive Gastric Electrical Stimulation Using a Newly Developed Wireless Gastrostimulator: A Pilot Animal Study

Kim SH, Kim HB, Chun HJ, Choi HS, Kim ES, Keum B, Seo YS, Jeen YT, Lee HS, Um SH, Kim CD

  • KMID: 2504010
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):410-416.
  • doi: 10.5056/jnm20063
Background/Aims Gastric electrical stimulation (GES) is a feasible modality for the treatment of gastroparesis; however, the presently available device requires invasive surgical implantation for long-term stimulation and repeated surgical procedure...
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Clinical Factors to Predict the Response to Concurrent Chemoradiotherapy and Survival in Esophageal Cancer Patients

Nam SY, Jeon SW, Lee SJ, Kwon YH, Lee HS, Kim SK

Background/Aims: Several clinical factors have been used to predict the response for concurrent chemoradiotherapy (CCRT); however, these factors are insufficient for prognostic predictions. We investigated clinical factors to assess whether...
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PD-L1 Testing in Gastric Cancer by the Combined Positive Score of the 22C3 PharmDx and SP263 Assay with Clinically Relevant Cut-offs

Park Y, Koh J, Na HY, Kwak Y, Lee KW, Ahn SH, Park DJ, Kim HH, Lee HS

Purpose We provide a comparison between 22C3 pharmDx and SP263 assay, for evaluating programmed death ligand 1 (PD-L1) expression in advanced gastric cancer (GC) patients. Materials and Methods The PD-L1 immunohistochemistry...
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Changes in performance of small bowel capsule endoscopy based on nationwide data from a Korean Capsule Endoscopy Registry

Kim SH, Lim YJ, Park J, Shim KN, Yang DH, Chun J, Kim JS, Lee HS, Chun HJ, Research Group for Capsule Endoscopy/Small Bowel Endoscopy

Background/Aims: Capsule endoscopy (CE) is widely used for the diagnosis of small bowel diseases. The clinical performance and complications of small bowel CE, including completion rate, capsule retention rate, and...
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Role of Serum Pepsinogen II and Helicobacter pylori Status in the Detection of Diffuse-Type Early Gastric Cancer in Young Individuals in South Korea

Baek SM, Kim N, Kwon YJ, Lee HS, Kim HY, Lee J, Yoon H, Shin CM, Park YS, Lee DH

Background/Aims: The utility of serum pepsinogen (sPG) I and the sPGI/II ratio as biomarkers for screening individuals with gastric cancer (GC) has not been established in Korea. The aim of...
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Performances of serum creatinine, C-reactive protein and white blood cell to predict urinary tract infection in febrile children younger than 24 months of age

Lee HS, Kwak YH, Park JW, Kim DK, Lee SU

Purpose: Differentiation of urinary tract infection (UTI) from viral infection is a critical challenge in febrile children in emergency departments (EDs). This study aimed to assess the predicting performances of...
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Evaluation of Commercial Immunochromatographic Test Kits for the Detection of Canine Distemper Virus

Yang DK, Kim HH, Lee J, Ji M, Oh S, Lee HS, Hyun BH

The rapid diagnosis of canine distemper virus (CDV) helps to determine the treatment of dogs in veterinary clinics. We evaluated the performance of seven commercial rapid immunochromatographic test (RICT) kits...
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