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Efficacy of S-pantoprazole 10 mg in the Symptom Control of Non-erosive Reflux Disease: A Phase III Placebo-controlled Trial

Cho YK, Choi MG, Park H, Kim JW, Lee DH, Ko KH, Kim SG, Jung HY, Hong SJ, Lee YC, Lee SH

  • KMID: 2514680
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):223-230.
  • doi: 10.5056/jnm19053
Background/Aims S-isomer (S) pantoprazole is more bioavailable and less dependent on cytochrome 2C19 than is racemic pantoprazole. We aim to evaluate the efficacy and safety of 10 mg S-pantoprazole for treatment...
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Current Status and Recent Update of Imaging Evaluation for Peri-Hilar Cholangiocarcinoma

Lee DH

Owing to the anatomic complexity of the hepatic hilum, it has been considered difficult to diagnose and treat peri-hilar cholangiocarcinoma. Currently, imaging studies, including contrastenhanced CT and MRI, play a...
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Regional Gaps in Health Status Estimated by Amenable Mortality Rate in Korea

Baek SJ, Kim H, Lee DH, Jeong HS

Background: This study aims to figure out the gaps in health status by estimating amenable mortality rate by region, reflecting the characteristics of Korea, and estimating the years of life...
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Large Animal Models in Pancreas and Biliary Disease

Jeong S, Park JS, Lee DH

Rodent models, which have played important roles in preclinical research of pancreas and biliary diseases, have some limitations to translating data from rodent models to human diseases. Large animal models...
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Estimating Baseline Incidence of Conditions Potentially Associated with Vaccine Adverse Events: a Call for Surveillance System Using the Korean National Health Insurance Claims Data

Huh K, Kim YE, Radnaabaatar M, Lee DH, Kim DW, Shin SA, Jung J

Background: Vaccines against coronavirus disease 2019 (COVID-19) are raising concerns about vaccine safety, particularly in the context of large-scale immunization. To address public concerns, we measured the baseline incidence rates...
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Compositional and Functional Changes in the Gut Microbiota in Irritable Bowel Syndrome Patients

Lee SM, Kim N, Yoon H, Kim YS, Choi SI, Park JH, Lee DH

Background/Aims: This study aimed to characterize the changes in the gut microbiota of irritable bowel syndrome (IBS) patients and to investigate the consequent alterations in bacterial functions. Methods: We performed 16S...
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Characteristics of the Gut Microbiome of Healthy Young Male Soldiers in South Korea: The Effects of Smoking

Yoon H, Lee DH, Lee JH, Kwon JE, Shin CM, Yang SJ, Park SH, Lee JH, Kang SW, Lee JS, Kim BY

Background/Aims: South Korean soldiers are exposed to similar environmental factors. In this study, we sought to evaluate the gut microbiome of healthy young male soldiers (HYMS) and to identify the...
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Retreatment of Chronic Hepatitis C Failed to Daclatasvir Plus Asunaprevir by Other Direct-acting Antivirals

Lee DH, Ryu SH, Myung Hj, Shin YJ, Lee SH, Park TY, Moon JS

The pegylated interferon plus ribavirin combination therapy has been used as the primary treatment for chronic hepatitis C (CHC) but fails to produce a sustained viral response (SVR) in many...
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The Effect of Adalimumab in Korean Patients with Refractory Noninfectious Uveitis

Park SE, Jun JW, Lee DH, Lee SC, Kim M

We sought to analyze the efficacy of adalimumab in active noninfectious uveitis, and evaluate its efficacy and safety for the management of refractory noninfectious uveitis in Korean patients. A retrospective...
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Radiofrequency Ablation Using a Separable Clustered Electrode for the Treatment of Hepatocellular Carcinomas: A Randomized Controlled Trial of a DualSwitching Monopolar Mode Versus a Single-Switching Monopolar Mode

Choi JW, Lee JM, Lee DH, Yoon JH, Kim YJ, Lee JH, Yu SJ, Cho EJ

Objective: This study aimed to prospectively compare the efficacy, safety, and mid-term outcomes of dual-switching monopolar (DSM) radiofrequency ablation (RFA) to those of conventional single-switching monopolar (SSM) RFA in the...
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Changes in Cecal Microbiota and Short-chain Fatty Acid During Lifespan of the Rat

Choi SI, Son JH, Kim N, Kim YS, Nam RH, Park JH, Song CH, Yu JE, Lee DH, Yoon K, Min H, Kim YR, Seok YJ

  • KMID: 2510071
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):134-146.
  • doi: 10.5056/jnm20148
Background/Aims The gut microbiota regulates intestinal immune homeostasis through host-microbiota interactions. Multiple factors affect the gut microbiota, including age, sex, diet, and use of drugs. In addition, information on gut microbiota...
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Treatment Outcomes of Patients with Head and Neck Squamous Cell Carcinoma of Unknown Primary

Park KS, Lim HR, Jeong SH, Lee DH, Lim SC

The purpose of this study was to evaluate clinical characteristics and treatment outcome of patients with head and neck squamous cell carcinoma of unknown primary (HNSCCUP), treated according to the...
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Rapid Response System Should Be Enhanced at Non-general Ward Locations: a Retrospective Multicenter Cohort Study in Korea

Kang BJ, Hong SB, Jeon K, Lee SM, Lee DH, Moon JY, Lee YJ, Kim JS, Park J, Ahn JJ

Background: A rapid response system (RRS) contributes to the safety of hospitalized patients. Clinical deterioration may occur in the general ward (GW) or in non-GW locations such as radiology or...
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Efficacy of Tegoprazan for Improving the Susceptibility of Antimicrobial Agents against Antibiotic-Resistant Helicobacter pylori

Lee JW, Kim N, Nam RH, Yu JE, Son JH, Lee SM, Lee DH

Background/Aims: Favorable outcomes of potassium-competitive acid blocker (PCAB)-containing eradication therapy have been reported. In fact, tegoprazan, a recently developed PCAB, was presumed to show good eradication efficacy even for resistant...
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Factors Related to Outcomes of Fecal Microbiota Transplantation in Patients with Clostridioides difficile Infection

Yoon H, Shim HI, Seol M, Shin CM, Park YS, Kim N, Lee DH

Background/Aims: The aim of this study was to evaluate factors related to outcomes of fecal microbiota transplantation (FMT) in patients with Clostridioides difficile infection (CDI) and viability of frozen stock...
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Radiologic Evaluation and Structured Reporting Form for Extrahepatic Bile Duct Cancer: 2019 Consensus Recommendations from the Korean Society of Abdominal Radiology

Lee DH, Kim B, Lee ES, Kim HJ, Min JH, Lee JM, Choi MH, Seo N, Choi SH, Kim SH, Lee SS, Park YS, Chung YE, The Korean Society of Abdominal Radiology

Radiologic imaging is important for evaluating extrahepatic bile duct (EHD) cancers; it is used for staging tumors and evaluating the suitability of surgical resection, as surgery may be contraindicated in...
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Comparison of flexural strength according to thickness between CAD/CAM denture base resins and conventional denture base resins

Lee DH, Lee JS

Purpose: The purpose of this study is to compare the flexural strength of CAD/CAM denture base resins with conventional denture base resins based on their thicknesses. Materials and Methods: For...
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The Influence of Knowledge of Human Papilloma Virus and Health Beliefs Related to Human Papilloma Virus Vaccination on the Intention of Cervical Cancer Prevention Behavior in Nurses

Lee DH, Eim YL, Choi SY

Purpose: This study aimed to examine the effects of knowledge of Human Papilloma Virus (HPV) and health beliefs related to HPV vaccination on the intention of cervical cancer prevention behavior...
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Role of microsurgery for treatment of posterior circulation aneurysms in the endovascular era

Kim DJ, Heo Y, Byun J, Park JC, Ahn JS, Lee DH, Kwun BD, Park W

Objective: Several studies have reported that the outcomes of endovascular treatment were superior to those of microsurgical treatment for posterior circulation aneurysms. Thus, this study compared outcomes of endovascular and...
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Acute Peripheral Vestibular Syndrome in Relapsing Polychondritis

Noh H, Lee DH, Shin JE, Kim CH

Relapsing polychondritis is a rare multisystemic autoimmune disorder of unknown etiology and characterized by recurrent episodes of inflammation affecting the cartilaginous tissues. Otologic manifestation such as auricular chondritis is one...
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