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Comparison of Respiratory Outcome between the Surfactant without Endotracheal Tube Intubation and the Intubation-SurfactantExtubation Techniques in Extremely Low Gestational Age Neonates with Respi­ratory Distress Syndrome

Cha T, Jeong J, Lee BS, Kim EAR, Kim KS, Jung E

Objective: The aim of this study was to determine whether there were differences in respiratory out comes of extremely low gestational age neonates according to the surfactant without endotracheal tube...
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Targeting Risk Factors for the Control of Central Line-Associated Bloodstream Infection in the Neonatal Intensive Care Unit: A Single Tertiary Center Experience

Jeong J, Kwun Y, Kim Mj, Choi SH, Jung E, Lee BS, Kim KS, Kim EAR

Purpose: The aim of this study was to estimate the effect of targeting risk factors for the control of central line-associated bloodstream infection (CLABSI) among high-risk infants in a tertiary...
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Survival and Morbidities in Infants with Birth Weight Less than 500 g: a Nationwide Cohort Study

Hwang JH, Jung E, Lee BS, Kim EAR, Kim KS

Background: This study aimed to investigate the survival and morbidities of infants in the Korean Neonatal Network (KNN) with birth weight (BW) < 500 g. Methods: The demographic and clinical data...
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Intestinal Perforation as a Paradoxical Reaction to Antitubercular Therapy: A Case Report

Kang SH, Moon HS, Park JH, Kim JS, Kang SH, Lee ES, Kim SH, Lee BS, Sung JK, Jeong HY, Lee KH

Paradoxical reactions to tuberculosis (TB) treatment are characterized by an initial improvement of the clinical symptoms followed by clinical or radiological deterioration of existing tuberculous lesions, or by development of...
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Should We Delay Urodynamic Study When Patients With Spinal Cord Injury Have Asymptomatic Pyuria?

Kim E, Lee HJ, Kim O, Park IS, Lee BS

Objective To assess the incidence of urinary tract infection (UTI) with post-urodynamic study (post-UDS) in patients with spinal cord injury (SCI) and study its relationship with pre-UDS pyuria. Methods Patients with...
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Continuing besifovir dipivoxil maleate versus switching from tenofovir disoproxil fumarate for treatment of chronic hepatitis B: Results of 192-week phase 3 trial

Song DS, Kim W, Ahn SH, Yim HJ, Jang JY, Kweon YO, Cho YK, Kim YJ, Hong GY, Kim DJ, Jung YK, Sohn JH, Lee JW, Park SJ, Lee BS, Kim JH, Kim HS, Yoon SK, Kim MY, Lee KS, Lim YS, Lee WS, Yang JM, Kim KH, Han KH, Um SH

Background/Aims: Besifovir dipivoxil maleate (BSV), an acyclic nucleotide phosphonate, shows potent antiviral activity against hepatitis B virus. Our previous 48-week trial revealed that BSV has comparable antiviral efficacy to tenofovir...
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Association between new-onset liver cirrhosis and suicide risk in South Korea: A nationwide cohort study

Jang SY, Rou WS, Kim SH, Lee BS, Eun HS

Background/Aims: Current evidence suggests that liver cirrhosis (LC) causes severe psychological stress and depression, which are risk factors for suicide. Although previous studies reported the association between LC and suicidal...
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Effectiveness and safety of elbasvir/grazoprevir in Korean patients with hepatitis C virus infection: a nationwide real-world study

Jang ES, Kim KA, Kim YS, Kim IH, Lee BS, Lee YJ, Chung WJ, Jeong SH

Background/Aim: This study aimed to establish the real-world effectiveness and safety of grazoprevir/elbasvir (EBR/GZR) therapy in South Korea. Methods: A total of 242 patients with chronic hepatitis C virus (HCV) genotype...
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Management of Persistent Pulmonary Hypertension in Preterm Infants

Lee BS

Persistent pulmonary hypertension of the newborn (PPHN) is a consequence of the failure of a decrease in the elevated pulmonary vascular resistance after birth. Pulmonary vasodilators, including inhaled nitric oxide...
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Perinatal outcome of fetuses with congenital high airway obstruction syndrome: a single-center experience

Jeong SH, Lee MY, Kang OJ, Kim R, Chung JH, Won HS, Lee PR, Jung E, Lee BS, Choi WJ, Lee YS

Objective To report our experience with management of fetuses with congenital high airway obstruction syndrome (CHAOS). Methods We retrospectively reviewed the cases of fetuses who were prenatally diagnosed and postnatally confirmed...
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Surgical Interventions and Clinical Outcomes of Patients with Trisomy 18: a Single Center Experience

Oh MY, Lee BS, Cha T, Jeong J, Jung E, Kim EAR, Kim KS, Lee BH, Yoo HW

Objective: The purpose of this study was to investigate the impact of surgical interventions on the survival rate of the trisomy 18 and to provide the clinical information of the...
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Response to Inhaled Nitric Oxide and Clinical Outcome in Very Low Birth Weight Infants with Early Pulmonary Hypertension

Cho JY, Lee BS, Oh MY, Cha T, Jeong J, Jung E, Kim AR, Kim KS

Purpose: To determine the efficacy of inhaled nitric oxide (iNO) in very low birth weight (VLBW) infants with early pulmonary hypertension (PH). Methods: We reviewed the medical records of 22 preterm...
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Changes in the Trend in Bladder Emptying Methods in Patients With Spinal Cord Injury: A 20-Year Single-Center Retrospective Study

Oh SW, Jung JH, Cho IK, Lee HJ, Kwon SH, Lee BS

Objective To review trends in bladder emptying methods over a 20-year period in patients with spinal cord injury (SCI) by severity according to the American Spinal Injury Association impairment scale...
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Evolving Indication of Meniscal Allograft Transplantation

Lee BS, Bin SI, Kim T

The first human meniscal allograft transplantations (MATs) were performed 30 years ago. In the early era, candidates were limited to patients who have favorable joint conditions. MAT is currently indicated...
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Current Status of Neonatologist Staffing and Workload in Korean Neonatal Intensive Care Units

Lee BS, Lim JW, Choi YS, Kim KS

Purpose: To identify the recent status of the neonatologist and their workload in neonatal intensive care unit (NICU) in Korea. Methods: On October 2018, a survey was conducted on the statistics...
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Cumulative Effects of Constituents from the Mushroom Calvatia nipponica on the Contractility of Penile Corpus Cavernosum Smooth Muscle

Lee S, Kim MJ, Lee BS, Ryoo R, Kim HK, Kim KH

Calvatia nipponica, a puffball mushroom (Agaricaceae), is thought to be an aphrodisiac, as this mushroom is traditionally known to improve sexual function in males. As part of the systematic study...
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Energy Efficiency and Patient Satisfaction of Gait With Knee-Ankle-Foot Orthosis and Robot (ReWalk)-Assisted Gait in Patients With Spinal Cord Injury

Kwon SH, Lee BS, Lee HJ, Kim EJ, Lee JA, Yang SP, Kim TY, Pak HR, Kim HK, Kim HY, Jung JH, Oh SW

Objective To compare the energy efficiency of gait with knee-ankle-foot orthosis (KAFO) and robot-assisted gait and to develop a usability questionnaire to evaluate the satisfaction of walking devices in paraplegic...
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A Case of Bony Defect of the Anterior External Auditory Canal Wall Causing Ear Fullness

Lee JK, Lee BS, Jang SK, Park SK

A congenital defect of the anterior wall of the external auditory canal (EAC) is known as foramen of Huschke. The tympanic bone is incompletely developed and has a U shape...
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A Novel COL4A1 Mutation in a Neonate with Intrauterine Intraventricular Hemorrhage and Porencephaly

Noh J, Jung E, Jung AY, Lee BH, Lee BS, Kim EAR, Kim KS

Collagen type IV alpha 1 (COL4A1) plays an important role in construction of the basement membranes of all human tissues, especially vessels. Mutations in COL4A1 lead to various multisystemic...
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Refractory Hepatic Hydrothorax in Chronic Hepatitis C Controlled by Direct-acting Antivirals

Kim MH, Kim DK, Eun HS, Rou WS, Kim SH, Lee BS

Hepatic hydrothorax is a transudative pleural effusion that complicates advanced liver cirrhosis. Patients refractory to medical treatment plus salt restriction and diuretics are considered to have refractory hepatic hydrothorax and...
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