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Efficacy and Safety of DWJ1252 Compared With Gasmotin in the Treatment of Functional Dyspepsia: A Multicenter, Randomized, Double-blind, Active-controlled Study

Park JH, Lee KN, Lee OY, Choi MG, Chung H, Choi SC, Kim N, Park H, Sung IK, Sohn CI, Jee SR, Jang JY, Rhee PL, Park MI, Kwon JG, Park KS, Lee KJ, Lee JS

  • KMID: 2510066
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):87-96.
  • doi: 10.5056/jnm20061
Background/Aims Prokinetics such as mosapride citrate CR (conventional-release; Gasmotin) are commonly used in functional dyspepsia (FD). This study aims to evaluate the efficacy and safety of once-a-day mosapride citrate SR (DWJ1252),...
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Multidisciplinary and Multisociety Practice Guideline on Reprocessing Flexible Gastrointestinal Endoscopes and Endoscopic Accessories

Cheung DY, Jang BI, Kim SW, Kim JH, Kim HK, Shin JE, Yoon WJ, Lee YK, Chung KH, Cho SJ, Shin HP, Cho SY, Shin WG, Choi KD, Kim BW, Kwon JG, Yang HC, Gweon TG, Kim HG, Ahn DW, Cho KB, Kim SH, Hwang KH, Im HH

The area of endoscopic application has been continuously expanded since its introduction in the last century and the frequency of its use also increased stiffly in the last decades. Because...
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2019 Seoul Consensus on Esophageal Achalasia Guidelines

Jung HK, Hong SJ, Lee OY, Pandolfino J, Park H, Miwa H, Ghoshal UC, Mahadeva S, Oshima T, Chen M, Chua ASB, Cho YK, Lee TH, Min YW, Park CH, Kwon JG, Park MI, Jung K, Park JK, Jung KW, Lim HC, Jung DH, Kim DH, Lim CH, Moon HS, Park JH, Choi SC, Suzuki H, Patcharatrakul T, Wu JCY, Lee KJ, Tanaka S, Siah KTH, Park KS, Kim SE, The Korean Society of Neurogastroenterology and Motility

  • KMID: 2500676
  • J Neurogastroenterol Motil.
  • 2020 Apr;26(2):180-203.
  • doi: 10.5056/jnm20014
Esophageal achalasia is a primary motility disorder characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Achalasia is a chronic disease that causes progressive irreversible loss of...
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Clinical Practice Guidelines for Functional Dyspepsia in Korea

Oh JH, Kwon JG, Jung HK, Tae CH, Song KH, Kang SJ, Kim SE, Jung K, Kim JS, Park JK, Bang KB, Baeg MK, Shin JE, Shin CM, Lee JY, Lim HC, Functional Dyspepsia Research Group, Clinical Practice Guidelines Group Under the Korean Society of Neurogastroenterology and Motility

  • KMID: 2500648
  • J Neurogastroenterol Motil.
  • 2020 Jan;26(1):29-50.
  • doi: 10.5056/jnm19209
Functional dyspepsia (FD) is a chronic upper gastrointestinal (GI) symptom complex that routine diagnostic work-up, such as endoscopy, blood laboratory analysis, or radiological examination, fails to identify a cause. It...
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The Goldilocks technique: An alternative method to construct a breast mound after prosthetic breast reconstruction failure

Zavala KJ, Kwon JG, Han HH, Kim EK, Eom JS

The Goldilocks technique for breast reconstruction utilizes redundant mastectomy flap tissue to construct a breast mound. This technique is suitable for women who decline, or are poor candidates for, traditional...
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The efficacy and safety of irsogladine maleate in nonsteroidal anti-inflammatory drug or aspirin-induced peptic ulcer and gastritis

Shim KN, Kim JI, Kim N, Kim SG, Jo YJ, Hong SJ, Shin JE, Kim GH, Park KS, Choi SC, Kwon JG, Kim JH, Kim HJ, Kim JW

BACKGROUND/AIMS: Irsogladine maleate, an enhancer of gastric mucosal protective factors, has demonstrated its efficacy for various gastric mucosal injuries. The aim of this study was to evaluate the efficacy and...
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Appropriate Prophylactic Antibiotic Use in Clean Wound Surgery Under Local Anesthesia

Cha HG, Kwon JG, Han HH, Eom JS, Kim EK

BACKGROUND: Although guidelines to prevent surgical site infections (SSIs) were published more than a decade ago, prophylactic antibiotics are still used subjectively in clinical practice. In this study, we evaluated...
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Self-reported Food Intolerance in Korean Patients With Irritable Bowel Syndrome

Lee HJ, Kim HJ, Kang EH, Jung KW, Myung SJ, Min YW, Choi CH, Ryu HS, Choi JK, Kwon JG, Hong KS, Park KS

  • KMID: 2449094
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):222-232.
  • doi: 10.5056/jnm18125
BACKGROUND/AIMS: Various foods trigger and/or worsen the symptoms of irritable bowel syndrome (IBS). However, Korean food-related gastrointestinal (GI) symptoms in IBS patients have not yet been investigated. This study aims...
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Functional Dyspepsia

Oh JH, Kwon JG

Dyspepsia is a common problem, and when dyspeptic symptoms develop within a short period of time, organic diseases such as gastroesophageal reflux disease, peptic ulcer diseases, pancreatoduodenal diseases, and gastrointestinal...
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Obesity and Functional Gastrointestinal Disorders

Lee JY, Kwon JG, Kim SE, Diet, Obesity, and Metabolism Research Group of Korean Society of Neurogastroenterology and Motility

The prevalence of obesity and functional gastrointestinal disorders (FGIDs) is increasing worldwide. Obesity has been linked to gastroesophageal reflux disease, irritable bowel syndrome, functional dyspepsia, and various FGIDs. However, the...
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What Is Appropriate Upper Endoscopic Interval Among Dyspeptic Patients With Previously Normal Endoscopy? A Multicenter Study With Bayesian Change Point Analysis

Kim JW, Jung KW, Kwon JG, Lee JB, Park JK, Bang KB, Tae CH, Oh JH

  • KMID: 2460484
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):544-550.
  • doi: 10.5056/jnm19063
BACKGROUND/AIMS: Appropriate interval for performing follow-up endoscopy among dyspeptic patients without abnormal findings on previous endoscopy is unclear. We analyzed the multicenter-collected data from the Korean Society of Neurogastroenterology and...
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A Double-blind, Randomized, Multicenter Clinical Trial Investigating the Efficacy and Safety of Esomeprazole Single Therapy Versus Mosapride and Esomeprazole Combined Therapy in Patients with Esophageal Reflux Disease

Lee JY, Kim SK, Cho KB, Park KS, Kwon JG, Jung JT, Kim EY, Jang BI, Lee SH, Daegu-Gyeongbuk Gastrointestinal Study Group (DGSG)

  • KMID: 2433522
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):218-228.
  • doi: 10.5056/jnm16100
BACKGROUND/AIMS: We aim to evaluate the efficacy and safety of combination therapy in erosive reflux disease (ERD) patients by comparing endoscopic healing rates according to the Los Angeles classification for...
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Nationwide Multicenter Study for Overlaps of Common Functional Gastrointestinal Disorders in Korean Patients With Constipation

Park KS, Jee SR, Lee BE, Hong KS, Shin JE, Na SY, Kwon JG, Choi SC, Kim YS, Lee HS, Lee TH, Kim KO, Choi J, Moon HS, Kim YS, Park MI, Park SJ, Park SY, Hong SN, Constipation Research Group of Korean Society of Neurogastroenterology and Motility

  • KMID: 2395426
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):569-577.
  • doi: 10.5056/jnm17033
BACKGROUND/AIMS: In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we...
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A Case of Gastro-Gastric Intussusception Secondary to Primary Gastric Lymphoma

Jo HH, Kang SM, Kim SH, Ra M, Park BK, Kwon JG, Kim EY, Jung JT, Kim HG, Ryoo HM, Kang UR

In adults, most intussusceptions develop from a lesion, usually a benign or malignant neoplasm, and can occur at any site in the gastrointestinal tract. Intussusception in the proximal gastrointestinal tract...
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Association between Smoking and the Progression of Computed Tomography Findings in Chronic Pancreatitis

Lee JW, Kim HG, Lee DW, Han J, Kwon HY, Seo CJ, Oh JH, Lee JH, Jung JT, Kwon JG, Kim EY

BACKGROUND/AIMS: Smoking and alcohol intake are two well-known risk factors for chronic pancreatitis. However, there are few studies examining the association between smoking and changes in computed tomography (CT) findings...
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Efficacy of DA-9701 (Motilitone) in Functional Dyspepsia Compared to Pantoprazole: A Multicenter, Randomized, Double-blind, Non-inferiority Study

Jung HK, Lee KJ, Choi MG, Park H, Lee JS, Rhee PL, Kim N, Park KS, Choi SC, Lee OY, Huh KC, Song GA, Hong SJ, Sohn CI, Jung HY, Lee YC, Rew JS, Jee SR, Kwon JG

  • KMID: 2203579
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):254-263.
  • doi: 10.5056/jnm15178
BACKGROUND/AIMS: The effect of proton pump inhibitors (PPI) in Asian functional dyspepsia (FD) patients has not been well established as in Western countries. DA-9701, a novel prokinetic agent, stimulates gastric...
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Comparison between Endoscopic Therapy and Medical Therapy in Peptic Ulcer Patients with Adherent Clot: A Multicenter Prospective Observational Cohort Study

Kim SH, Jung JT, Kwon JG, Kim EY, Lee DW, Jeon SW, Park KS, Lee SH, Park JB, Ha CY, Park YS, Daegu-Gyeongbuk Gastrointestinal Study Group (DGSG)

BACKGROUND/AIMS: The optimal management of bleeding peptic ulcer with adherent clot remains controversial. The purpose of this study was to compare clinical outcome between endoscopic therapy and medical therapy. We...
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Clinical Outcomes of the Endoscopic Submucosal Dissection of Early Gastric Cancer Are Comparable between Absolute and New Expanded Criteria

Shin KY, Jeon SW, Cho KB, Park KS, Kim ES, Park CK, Chung YJ, Kwon JG, Jung JT, Kim EY, Kim KO, Jang BI, Lee SH, Park JB, Yang CH

BACKGROUND/AIMS: Advances in endoscopic submucosal dissection (ESD) techniques have led to the development of expanded criteria for endoscopic resection of early gastric cancer (EGC). The aim of this study was...
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Trend in the Eradication Rates of Helicobacter pylori Infection in the Last 8 Years in Daegu: A Single Center Experience

Kim SH, Jung JT, Kwon JG, Kim EY, Kang SM, Song JE

BACKGROUND/AIMS: Helicobacter pylori eradication rates achieved by first-line triple treatment with proton pump inhibitor (PPI), clarithromycin, and amoxicillin have decreased to 70~85%, in part due to increasing antimicrobial resistance. This...
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Alterations of Colonic Contractility in an Interleukin-10 Knockout Mouse Model of Inflammatory Bowel Disease

Park JH, Kwon JG, Kim SJ, Song DK, Lee SG, Kim ES, Cho KB, Jang BI, Kim DH, Sin JI, Kim TW, Song IH, Park KS

  • KMID: 2381231
  • J Neurogastroenterol Motil.
  • 2015 Jan;21(1):51-61.
  • doi: 10.5056/jnm14008
BACKGROUND/AIMS: Inflammatory bowel disease is commonly accompanied by colonic dysmotility and causes changes in intestinal smooth muscle contractility. In this study, colonic smooth muscle contractility in a chronic inflammatory condition...
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