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Association between ALDH2 Polymorphism and Gastric Cancer Risk in a Korean Population

Choi CK, Kweon SS, Cho SH, Kim HY, Shin MH

The association between alcohol and gastric cancer is stronger in East Asians than in other ethnic groups, presumably due to an aldehyde dehydrogenase 2 (ALDH2) polymorphism. Therefore, we investigated the...
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Effect Modification of Acetaldehyde Dehydrogenase 2 rs671 Polymorphism on the Association between Alcohol Intake and Blood Pressure: the Dong-gu Study

Kim HY, Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Shin MH

BACKGROUND: Elevated blood pressure is a major preventable cause of cardiovascular diseases. Alcohol consumption is a well-known risk factor of elevated blood pressure. The aldehyde dehydrogenase 2 (ALDH2) polymorphism is...
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Low serum 25-hydroxyvitamin D levels, tooth loss, and the prevalence of severe periodontitis in Koreans aged 50 years and older

Kim H, Shin MH, Yoon SJ, Kweon SS, Lee YH, Choi CK, Kim O, Kim YJ, Chung H, Kim OS

Purpose: Vitamin D deficiency may cause bone loss and increased inflammation, which are well-known symptoms of periodontal disease. This study investigated whether serum 25-hydroxyvitamin D (25(OH)D) levels are associated with...
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Epidemiology of liver cancer in Korea

Kweon SS

The incidence rate of primary liver cancer in Korea, the majority of which is hepatocellular carcinoma, has been decreasing steadily since 1999. However, Korea still has one of the highest...
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Non-linear Relationship Between Body Mass Index and Lower Urinary Tract Symptoms in Korean Males

Choi CK, Kim SA, Jeong JA, Kweon SS, Shin MH

OBJECTIVES: The purpose of this study was to evaluate the association between body mass index (BMI) and severe lower urinary tract symptoms (LUTS) in Korean males. METHODS: This study was conducted...
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Association of Falls and Fear of Falling with Mortality in Korean Adults: The Dong-gu Study

Oh J, Choi CK, Kim SA, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Shin MH

This study evaluated the association between falls and the fear of falling (FOF) with the risk of all-cause mortality in Korean adults. The study enrolled 4,386 subjects aged 50 years...
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Novel Germline Mutations of BRCA1 and BRCA2 in Korean Familial Breast Cancer Patients

Kim HN, Shin MH, Lee R, Park MH, Kweon SS

Breast cancer is the second most common cancer in Korean women. Germline mutations in the BRCA1 and BRCA2 genes cause hereditary breast cancer and are detected in 15–20% of hereditary...
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The Association between the Apolipoprotein E Gene Polymorphism and All-cause Mortality in the Korean Population

Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Kim HY, Shin MH

BACKGROUND: Apolipoprotein E (APOE) gene polymorphism is associated with neurodegenerative and cardiovascular diseases. Although the effects of the gene differ by ethnic group, few studies have examined Asians. Therefore, the...
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Patient's Cognitive Function and Attitudes towards Family Involvement in Cancer Treatment Decision Making: A Patient-Family Caregiver Dyadic Analysis

Shin DW, Cho J, Roter DL, Kim SY, Park JH, Yang HK, Lee HW, Kweon SS, Kang YS, Park K

PURPOSE: Older patient populations commonly have cognitive impairment, which might impact decisional capacity. We examined patients and family caregivers preferences for family involvement in treatment decision making assuming different level...
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Association between Plasma Pentraxin 3 Levels and Bone Mineral Density in Elderly Koreans: the Dong-gu Study

Lee R, Ahn HR, Shin MH, Kim HN, Lee YH, Choi SW, Kweon SS

BACKGROUND: We investigated the association between pentraxin 3 (PTX3), a novel inflammatory marker, and bone mineral density (BMD) in the general Korean population. METHODS: We selected a sub-cohort of 1,440 subjects...
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Updates on Cancer Epidemiology in Korea, 2018

Kweon SS

Cancer is a major cause of morbidity and the most common cause of death in Korea. There are currently approximately 200,000 incident cancer cases and 78,000 individuals die from cancer...
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Association between Serum Parathyroid Hormone Levels and the Prevalence of Atrial Fibrillation: the Dong-gu Study

Lee KH, Shin MH, Park HW, Cho JG, Kweon SS, Lee YH

BACKGROUND AND OBJECTIVES: We aimed to investigate the association between serum parathyroid hormone (PTH) levels and the prevalence of atrial fibrillation (AF) in a population based study. METHODS: This study included...
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Detection of Familial Hypercholesterolemia Using Next Generation Sequencing in Two Population-Based Cohorts

Kim HN, Kweon SS, Shin MH

We aimed to evaluate the prevalence of familial hypercholesterolaemia (FH) in a subject with hypercholesterolaemia from two population-based cohorts in South Korea. A total of 283 subjects with total cholesterol...
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Effect of Family History of Diabetes on Hemoglobin A1c Levels among Individuals with and without Diabetes: The Dong-gu Study

Lee YH, Shin MH, Nam HS, Park KS, Choi SW, Ryu SY, Kweon SS

PURPOSE: We investigated associations between family history of diabetes (FHD) and hemoglobin A1c (HbA1c) level, among people with and without diabetes. MATERIALS AND METHODS: In total, 7031 people without diabetes and...
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Carotid Atherosclerosis and Electrocardiographic Left Ventricular Hypertrophy in the General Population: The Namwon Study

Kim NH, Shin MH, Kweon SS, Ko JS, Lee YH

This study aimed to investigate the relationship between carotid atherosclerosis and left ventricular hypertrophy on electrocardiogram (ECG-LVH) on adults living in the community. A total of 9,266 adults who participated...
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A Gender-Specific Association between Self-Reported Snoring and Hemoglobin A1c Levels in a General Population without Type 2 Diabetes Mellitus

Lee YH, Kweon SS, Choi JS, Nam HS, Park KS, Choi SW, Oh SH, Kim SA, Shin MH

PURPOSE: We explored whether a gender difference was evident in terms of the associations of snoring with hemoglobin A1c (HbA1c) and homeostatic model assessment-insulin resistance (HOMA-IR) levels in a healthy...
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Association between Serum 25-hydroxyvitamin D Levels and Type 2 Diabetes in Korean Adults

Nam H, Kim HY, Choi JS, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Oh SH, Kim SA, Shin MH

Previous studies have suggested that a vitamin D deficiency increases the risk of type 2 diabetes. This study evaluated the association between serum vitamin D levels and type 2 diabetes...
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Association between Vitamin D Status and Risk of Peripheral Arterial Disease: The Dong-gu Study

Oh SH, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Shin MH

Low levels of vitamin D have been associated with increased cardiovascular disease risk. However, few studies have evaluated the association between vitamin D status and peripheral arterial disease (PAD). We...
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Association of APOE Genotype with Bone Mineral Density in Men and Women: The Dong-gu and Namwon Studies

Kim SA, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Kim HN, Song HR, Oh SH, Cauley JA, Shin MH

Many studies have investigated relationships between APOE genotype and bone mineral density (BMD). However, the results of these studies have been inconsistent. Few studies have been carried out in Asian...
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APOE Polymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study

Yun YW, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Kim HN, Cauley JA, Shin MH

We evaluated the association of the APOE polymorphism with serum C-reactive protein levels and white blood cell count in two large population-based studies in Korean. The datasets included the Dong-gu...
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