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Clinical Aspects of Neurobehavioral Symptoms of Dementia

Yang Y, Kandiah N, Kim S, Kwak YT

Neurobehavioral symptoms of dementia (NBSD) are very common and are significant symptoms of the illness, contributing most to caregiver burdens and often resulting in premature institutionalization of the person with...
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FDG PET Findings according to Wandering Patterns of Patients with Drug-naïve Alzheimer's Disease

Yang Y, Kwak YT

BACKGROUND AND PURPOSE: To explore anatomic substrate of specific wandering patterns in patients with Alzheimer's disease (AD) by performing positron emission tomography with 18F fluorodeoxyglucose positron emission tomography (FDG PET). METHODS:...
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A Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial for Efficacy of Acetyl-L-carnitine in Patients with Dementia Associated with Cerebrovascular Disease

Yang Y, Choi H, Lee CN, Kim YB, Kwak YT

BACKGROUND AND PURPOSE: Acetyl-L-carnitine (ALC) is a widely used drug for various neurodegenerative diseases including dementia. The aim of the present study was to elucidate the efficacy of ALC in...
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18F-FP-CIT Positron Emission Tomography for Correlating Motor and Cognitive Symptoms of Parkinson's Disease

Yang Y, Cheon M, Kwak YT

BACKGROUND AND PURPOSE: The aim of this paper was to investigate the utility of 18F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane (FP-CIT) positron emission tomography (PET) for evaluating the severity of Parkinson's disease (PD) according...
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Anxiety in Dementia

Kwak YT, Yang Y, Koo MS

Until recently, there is considerable mess regarding the nature of anxiety in dementia. However, anxiety is common in this population affecting from 8% to 71% of prevalence, and resulted in...
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Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer's Dementia

Yang Y, Kwak YT

BACKGROUND AND PURPOSE: Cognitive training is known to be an effective tool in enhancing cognitive functioning. Research has also shown that playing video game improves certain aspects of visual attention...
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Is Parkinson's Disease with History of Agent Orange Exposure Different from Idiopathic Parkinson's Disease?

Yang Y, Cheon M, Kwak YT

BACKGROUND AND PURPOSE: During Vietnam War, many Korean soldiers were dispatched to fight in the war where they were exposed to Agent Orange. Until now, there exist only limited evidence...
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The Neuropsychological Characteristics in Early Stage of Alzheimer's Patients with Depression

Yang Y, Kwak YT

BACKGROUND AND PURPOSE: Although depression is a common psychiatric symptom in Alzheimer's disease (AD), there has not been a lot of research on neuropsychological characteristics of this symptom. To determine...
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Neurocognitive Model of Delusion: Two-Factor Theory

Kwak YT

The underlying nature of delusions remains unclear despite their importance in psychopathology. Here we present a review of the neurocognitive model of delusions from a cognitive neuroscience viewpoint. There have...
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Depression and Cognition

Kwak YT, Yang Y, Koo MS

Depression is a relatively common agonizing psychiatric disorder that affects the way we feel and think about ourselves and the world around us. Cognitive theories of depression have long posited...
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Valve-Sparing Root Replacement: Aortic Root Remodeling with External Subvalvular Ring Annuloplasty

Cho SH, Kim DH, Kwak YT

The original valve-sparing procedures for aortic root aneurysms were remodeling and reimplantation of the aortic root. The remodeling technique provides more physiologic movement of the cusps within 3 reconstructed neo-sinuses,...
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Wandering in Dementia

Kwak YT, Yang Y, Koo MS

Wandering is acknowledged as one of the most complex, challenging, and potentially dangerous dementia-related behaviors, and can result in elopement, injury, and even death. For the healthy people, walking is...
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Understanding of Antipsychotics in Elderly Patients with Dementia

Kwak YT, Yang Y, Jang HR

Elderly patients affected with dementia frequently accompany delusions, hallucinations and other psychotic symptoms. As such, these patients are commonly prescribed antipsychotic medications for the treatment of psychosis. However, in recent...
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The Relationship between Geriatric Depression Scale Structure and Cognitive-Behavioral Aspects in Patients with Alzheimer's Disease

Kwak YT, Song SH, Yang Y

BACKGROUND AND PURPOSE: Although the 15-item Geriatric Depression Scale (GDS15) is a widely used depression screening questionnaire, the implications of the GDS15 in patients with Alzheimer's disease (AD) are questionable....
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Late-Onset Psychosis; Is It Real?

Kwak YT, Yang Y, Koo MS

The nature of late-onset psychosis in the absence of a dementia or secondary to organic dysfunctions in the fifth decade of life and beyond is contentious and unresolved. Different terminologies,...
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Neuropsychological Characteristics of Wandering in Patients with Drug-naive Alzheimer's Disease

Yang Y, Hwang I, Kwak YT

BACKGROUND: Wandering represents one of a major problem occurring in patients with Alzheimer's disease (AD). To find the disproportionate neuropsychological deficit and behavioral psychological symptoms in dementia (BPSD) of AD...
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Delusions in Alzheimer's Disease

Kwak YT, Yang Y, Koo MS

Alzheimer's disease (AD) is associated with cognitive and functional impairment as well as neuropsychiatric complications, including psychotic symptoms such as delusions and hallucinations. Recent studies strongly suggest that delusions should...
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Depression in Alzheimer's Disease

Kwak YT, Yang Y, Koo MS

Depression is one of the most common psychiatric complications of Alzheimer disease (AD), affecting from 30% to 50% of prevalence, with most estimates in the 20-30% range. Because of having...
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Normothermic Cardiac Surgery with Warm Blood Cardioplegia in Patient with Cold Agglutinins

Cho SH, Kim DH, Kwak YT

  • KMID: 2115238
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Apr;47(2):133-136.
Cold agglutinins are predominately immunoglobulin M autoantibodies that react at cold temperatures with surface antigens on the red blood cell. This can lead to hemagglutination at low temperatures, followed by...
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Missing Data Analysis in Drug-Naive Alzheimer's Disease with Behavioral and Psychological Symptoms

Kwak YT, Yang Y, Park SG

PURPOSE: To clarify the effects of missing values due to behavioral and psychological symptoms in dementia (BPSD) in Alzheimer's disease (AD) patients on the neuropsychological tests, this study describes the...
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