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Clinical characteristics of congenital pulmonary airway malformation of the lungs: A single-center study

Yoo HW, Kim SH, Kim YM, Kwak MJ, Kim HY

Purpose: Congenital pulmonary airway malformation (CPAM) is a rare developmental abnormality of the lungs. We investigated clinical characteristics of CPAM based on patient age at diagnosis. Methods: In this retrospective study,...
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Diagnostic Performance of Serum Asialo α1 -Acid Glycoprotein Levels to Predict Liver Cirrhosis

Lim DH, Kim M, Jun DW, Kwak MJ, Yoon JH, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS, Kang BK

Background/Aims: To date, studies on various noninvasive techniques have been suggested to evaluate the degree of liver fibrosis. We aimed to investigate the diagnostic performance of se-rum asialo α1-acid glycoprotein...
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Identification of a novel variant in the PHEX gene using targeted gene panel sequencing in a 24-month-old boy with hypophosphatemic rickets

Jo HY, Shin JH, Kim HY, Kim YM, Lee H, Bae MH, Park KH, Jang JH, Kwak MJ

Familial hypophosphatemic rickets (FHR) is a disorder characterized by phosphate wasting and hypophosphatemia due to defects in renal phosphate transport regulation. There are 4 known inherited forms of FHR that...
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Bilateral Acute Retinal Necrosis and Encephalomalacia Due to Herpes Simplex Virus Infection in a Premature Infant

Bae MH, Lee NR, Han YM, Yoon L, Kim YM, Byun SY, Lee JJ, Kwon HJ, Kwak MJ, Park KH

Herpes simplex virus (HSV) is a common pathogen, that causes a broad spectrum of diseases, ranging from minor skin infections to severe encephalitis and widespread infections. Acute retinal necrosis (ARN),...
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A Novel c.6766_6767insAA Mutation in the Neurofibromin Gene in a Patient with Neurofibromatosis Type 1-Associated Glioblastoma

Yang EH, Kim YM, Kim KJ, Cha SH, Kwak MJ

Neurofibromatosis type 1 (NF-1) is an autosomal dominant neurocutaneous syndrome caused by mutations in the neurofibromin gene. NF-1 patients have a high risk of tumors, and optic glioma is the...
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National Trends in Smoking Cessation Medication Prescriptions for Smokers With Chronic Obstructive Pulmonary Disease in the United States, 2007-2012

Kwak MJ, Kim J, Bhise V, Chung TH, Petitto GS

OBJECTIVES: Smoking cessation decreases morbidity and mortality due to chronic obstructive pulmonary disease (COPD). Pharmacotherapy for smoking cessation is highly effective. However, the optimal prescription rate of smoking cessation medications...
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Transient Abnormalities on Magnetic Resonance Imaging after Absence Seizures

Yoo HW, Yoon L, Kim HY, Kwak MJ, Park KH, Bae MH, Lee Y, Nam SO, Kim YM

Magnetic resonance imaging (MRI) is recommended for patients with epileptic seizures to rule out an underlying focal lesion. However, abnormalities in idiopathic generalized epilepsy, including childhood absence epilepsy, cannot usually...
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Clinical genetics of defects in thyroid hormone synthesis

Kwak MJ

Thyroid dyshormonogenesis is characterized by impairment in one of the several stages of thyroid hormone synthesis and accounts for 10%–15% of congenital hypothyroidism (CH). Seven genes are known to be...
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Comparison of conservative therapy and steroid therapy for Bell's palsy in children

Yoo HW, Yoon L, Kim HY, Kwak MJ, Park KH, Bae MH, Lee Y, Nam SO, Kim YM

PURPOSE: Bell's palsy is characterized by sudden onset of unilateral facial weakness. The use of corticosteroids for childhood Bell's palsy is controversial. This study aimed to identify clinical characteristics, etiology,...
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Vitamin D deficiency in children aged 6 to 12 years: single center's experience in Busan

Roh YE, Kim BR, Choi WB, Kim YM, Cho MJ, Kim HY, Park KH, Kim KH, Chun P, Kim SY, Kwak MJ

PURPOSE: This study investigated the prevalence and risk factors associated with vitamin D deficiency in children. METHODS: We analyzed the medical records of 330 patients from the age of 6 to...
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Displaced Double-Layered Lateral Meniscus That Mimicked the Bucket-Handle Tear: a Case Report

Kwak MJ, Kim SK, Kim KJ, Lee BS, Kang J

Among the various types of congenital meniscal anomalies, the double-layered lateral meniscus is extremely rare. The double-layered meniscus consists of both the upper additional and the lower normal meniscus. As...
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The Effect of Behavior Inhibition System on Smart-Phone Addiction : The Mediation Roll of Depression

Jung DJ, Cho H, Park JW, Kwak MJ, Kim DJ

OBJECTIVES: This study was conducted to examine the mediating effect of depression on the relationship between behavior inhibition system (BIS) and smart-phone addiction (SA) in Korea. METHODS: An online survey was...
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A Leri-Weill dyschondrosteosis patient confirmed by mutation analysis of SHOX gene

Choi WB, Seo SH, Yoo WH, Kim SY, Kwak MJ

Leri-Weill dyschondrosteosis is characterized by SHOX deficiency, Madelung deformity, and mesomelic short stature. In addition, SHOX deficiency is associated with idiopathic short stature, Turner syndrome, and Langer mesomelic dysplasia. We...
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Radiological Features of a Fibro-Osseous Pseudotumor in the Digit: A Case Report

Kwak MJ, Kim SK, Lee SU, Jun SY, Lee AH

A fibro-osseous pseudotumor is a rare ossifying soft tissue lesion, which is thought to be a reactive rather than a neoplastic lesion, developing due to repeated trauma. The lesion mostly...
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Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam

Lee JH, Kim YM, Kwak MJ, Kim SY, Kim HJ, Cheon CK, Chung WY, Choi IJ, Hong SY, Chueh HW, Yoo JH

PURPOSE: This study investigated the incidence trends and associated factors of type 1 (T1DM) and type 2 diabetes mellitus (T2DM) in children and adolescents under 15 years of age in...
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A novel de novo mutation within PHEX gene in a young girl with hypophosphatemic rickets and review of literature

Cheon CK, Lee HS, Kim SY, Kwak MJ, Kim GH, Yoo HW

X-linked hypophosphatemia (XLH) is the most common form of familial hypophosphatemic rickets and it is caused by loss-of-function mutations in the PHEX gene. Recently, a wide variety of PHEX gene...
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Cause and incidence of eosinophilia in children: a single center study in one year

Kim KM, Bae MH, Kim YM, Cho MJ, Kwak MJ, Kim SH, Son SK, Park HJ, Kim HY

PURPOSE: Eosinophilia may be associated with various primary and reactive conditions. However, studies on the cause and incidence of eosinophilia in Korean children are rare. This study aimed to evaluate...
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The Role of AMPA Receptors in Synaptic Plasticity by Drugs of Abuse

Kwak MJ, Kim JH

Dopamine has long time considered as the main player in drug addiction. However, growing body of literature strongly supports a role for glutamate in addiction. 2-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors,...
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The Utility of Basal Serum Luteinizing Hormone Levels for Screening Central Precocious Puberty in Girls

Ju JK, Lee HL, Lee YA, Chung SK, Kwak MJ

  • KMID: 2320019
  • Yeungnam Univ J Med.
  • 2013 Dec;30(2):90-94.
BACKGROUND: This study was conducted to examine if basal luteinizing hormone (LH) levels could be useful for screening central precocious puberty (CPP) in girls. METHODS: A total of 90 girls under...
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Comparative Study of the Effects of Different Growth Hormone Doses on Growth and Spatial Performance of Hypophysectomized Rats

Kwak MJ, Park HJ, Nam MH, Kwon OS, Park SY, Lee SY, Kim MJ, Kim SJ, Paik KH, Jin DK

This study was designed to examine the effects of recombinant human growth hormone replacement on somatic growth and cognitive function in hypophysectomized (HYPOX) female Sprague-Dawley rats. Rats (5 per group)...
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