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Validation of Prediction Models for Mismatch Repair Gene Mutations in Koreans

Lee SY, Kim DW, Shin YK, Ihn MH, Lee SM, Oh HK, Ku JL, Jeong SY, Lee JB, Ahn S, Won S, Kang SB

PURPOSE: Lynch syndrome, the commonest hereditary colorectal cancer syndrome, is caused by germline mutations in mismatch repair (MMR) genes. Three recently developed prediction models for MMR gene mutations based on...
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Clinicopathological Features and Type of Surgery for Lynch Syndrome: Changes during the Past Two Decades

Son IT, Kim DW, Jeong SY, Shin YK, Ihn MH, Oh HK, Kang SB, Park KJ, Oh JH, Ku JL, Park JG

PURPOSE: The Korean Hereditary Tumor Registry, the first and one of the largest registries of hereditary tumors in Korea, has registered about 500 families with hereditary cancer syndromes. This study...
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Effects of granulocyte-colony stimulating factor and the expression of its receptor on various malignant cells

Moon HW, Kim TY, Oh BR, Hwang SM, Kwon J, Ku JL, Lee DS

BACKGROUND: Granulocyte-colony stimulating factor (G-CSF) is extensively used to improve neutrophil count during anti-cancer chemotherapy. We investigated the effects of G-CSF on several leukemic cell lines and screened for the...
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Biology of SNU Cell Lines

Ku JL, Park JG

  • KMID: 1743349
  • Cancer Res Treat.
  • 2005 Feb;37(1):1-19.
SNU (Seoul National University) cell lines have been established from Korean cancer patients since 1982. Of these 109 cell lines have been characterized and reported, i.e., 17 colorectal carcinoma, 12...
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The Effect of Gastrin and Cholecystokinin on the Growth of Pancreato-biliary Cancer Cell Lines

Jang JY, Kim SW, Yoon YS, Ku JL, Park YH, Park JG

  • KMID: 2004562
  • J Korean Surg Soc.
  • 2003 May;64(5):408-417.
PURPOSE: Gastrin and cholecystokinin (CCK) have been reported to play a role in the development and growth stimulation of gastrointestinal cancers including pancreatic cancer. METHODS: We investigated the effects of...
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Germline Mutation of Rb1 Gene in Korean Retinoblastoma Patients

Ku JL, Yu YS, Park JG

  • KMID: 2175466
  • J Korean Cancer Assoc.
  • 1997 Apr;29(2):291-298.
PURPOSE: Retinoblastoma is an intraocular tumor occurring almost exclusively in young children. Germline mutations in the Rb1 gene confer hereditary predisposition to retinoblastoma. To identify germline mutations in the Rb1...
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