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The Early Response to Dietary Therapy can Predict the Late Outcome in Children with Intractable Epilepsy

Lim Sy, Yum MS, Ahn H, Kim MJ, Jang HN, Ko TS

Background and Purpose Dietary therapy (DT), including the ketogenic diet (KD), is one of the nonpharmacological treatment options for patient with drug-resistant epilepsy. However, maintaining DT in patients without seizure...
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Psychological Impact of Quarantine on Caregivers at a Children's Hospital for Contact with Case of COVID-19

Kim H, Park KJ, Shin YW, Lee JS, Chung S, Lee T, Kim MJ, Jung J, Lee J, Yum MS, Lee BH, Koh KN, Ko TS, Lim E, Lee JS, Lee JY, Choi JY, Han HM, Shin WA, Lee NJ, Kim SH, Kim HW

Quarantine often provokes negative psychological consequences. Thus, we aimed to identify the psychological and behavioral responses and stressors of caregivers quarantined with young patients after a close contact to a...
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The Genetic Relationship between Paroxysmal Movement Disorders and Epilepsy

Ahn H, Ko TS

Seizures and movement disorders both involve abnormal movements and are often difficult to distinguish due to overlapping phenomenology and possible etiological commonalities. Paroxysmal movement disorders, which include three paroxysmal dyskinesias...
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Treatment of Children and Adolescents with Epilepsy with Atomoxetine

Park KJ, Ahn H, Yum MS, Ko TS, Kim HW

Objective The objective of this study was to assess the effectiveness and safety of atomoxetine in Korean children and adolescents with epilepsy. Methods We retrospectively reviewed the electronic medical records of...
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Altered Structural Network in Newly Onset Childhood Absence Epilepsy

Kim EH, Shim WH, Lee JS, Yoon HM, Ko TS, Yum MS

Background and Purpose: Recent quantitative neuroimaging studies of childhood absence epilepsy (CAE) have identified various structural abnormalities that might be involved in the onset of absence seizure and associated cognitive...
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Clinical Implications of Ketosis in Children with Benign Convulsions with Mild Gastroenteritis

Lee JY, Ryu JM, Lee JS, Ko TS, Yum MS

BACKGROUND AND PURPOSE: The pathophysiologic mechanisms underlying benign convulsions with mild gastroenteritis (CwG) in children remain unclear. We investigated the incidence of ketosis in CwG and whether this is related...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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Efficacy and Tolerability of Low-Dose Perampanel in Patients with Childhood-Onset Intractable Epilepsy

Park H, Ahn H, Jang HN, Kim HJ, Yum MS, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of perampanel as adjunctive therapy in childhood-onset refractory epilepsy. METHODS: We retrospectively reviewed the medical records of 110...
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A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years

Kwak M, Yeh HR, Yum MS, Kim HJ, You SJ, Ko TS

Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of...
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Experience of a Single Center in Treating Multiple Manifestations of Tuberous Sclerosis Complex with Everolimus

Ahn H, Yum MS, Jang HN, Song C, Ko TS

PURPOSE: The aim of this study was to evaluate the efficacy and tolerability of everolimus, an oral mammalian target of rapamycin (mTOR) inhibitor, for the treatment of tuberous sclerosis complex...
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Diagnosis of Tuberous Sclerosis Complex and Epilepsy Outcomes in Children with Fetal Cardiac Rhabdomyoma: A Long Term Follow-up Study

Kim D, Kim HJ, You SJ, Yum MS, Ko TS

PURPOSE: Prenatal diagnosis of cardiac rhabdomyoma is suggestive of the presence of tuberous sclerosis complex (TSC), which is commonly associated with epilepsy. This study investigated the diagnostic rate of TSC,...
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Magnetic Resonance Imaging and Clinical Results of Outside-in Anterior Cruciate Ligament Reconstruction: A Comparison of Fixed- and Adjustable-Length Loop Cortical Fixation

Ahn JH, Ko TS, Lee YS, Jeong HJ, Park JK

BACKGROUND: Cortical suspensory femoral fixation is commonly performed for graft fixation to the femur in anterior cruciate ligament (ACL) reconstruction using hamstring tendons. The purpose of this study was to...
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Two Cases of Hirayama Disease in a Pediatric Clinic

Ahn H, Yum MS, Kim HJ, Yeh HR, Ko TS

We report two pediatric cases with Hirayama disease—a 16-year-old boy with a left wrist drop and a 14-year-old-boy with weakness and muscle atrophy of right hand. Motor nerve conduction study...
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The Inaccuracy of Surface Landmarks for the Anterior Approach to the Cervical Spine in Southern Chinese Patients

Ko TS, Siu Hei Tse M, Wong KK, Wong WC

STUDY DESIGN: Observational study. PURPOSE: To assess the correlational accuracy between the traditional anatomic landmarks of the neck and their corresponding vertebral levels in Southern Chinese patients. OVERVIEW OF LITERATURE: Recent studies...
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Rufinamide in Patients with Childhood Onset Intractable Epilepsy

Ahn H, Yum MS, Yeh HR, Kim MJ, Ko TS

PURPOSE: This study is aimed to evaluate the effectiveness and tolerability of rufinamide as add-on therapy in patients with intractable epilepsies. METHODS: We retrospectively reviewed the medical records of 70 patients...
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Analysis of Parenting Stress, Coping and the Quality of Life for the Mother of Children Suffering from Epilepsy

Jung SJ, Ko TS, Yom YH

PURPOSE: The purpose of this study was to identify factors affecting the parenting stress, coping and the quality of life for the mother of children suffering from epilepsy. METHODS: Research subjects...
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Clinical Characteristics of Transplant-associated Encephalopathy in Children

Lee YJ, Yum MS, Kim EH, Kim MJ, Kim KM, Im HJ, Kim YH, Park YS, Ko TS

We aimed to analyze characteristics of encephalopathy after both hematopoietic stem cell and solid organ pediatric transplantation. We retrospectively reviewed medical records of 662 pediatric transplant recipients (201 with liver...
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Identification of two novel Duchenne muscular dystrophies mutations in patients with Becker muscular dystrophy

Kim D, Kim YM, Seo GH, Kim GH, Yoo HW, Yum MS, Ko TS, Lee BH

Duchenne and Becker muscular dystrophies (DMD and BMD, respectively) are X-linked neuromuscular disorders characterized by progressive muscle weakness and severe skeletal muscle degeneration. BMD is a milder form with a...
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Genotype-Phenotype Correlation of SMN1 and NAIP Deletions in Korean Patients with Spinal Muscular Atrophy

Ahn EJ, Yum MS, Kim EH, Yoo HW, Lee BH, Kim GH, Ko TS

BACKGROUND AND PURPOSE: Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. Most SMA patients have a homozygous deletion in survival of...
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Two cases of familial cerebral cavernous malformation caused by mutations in the CCM1 gene

Yang IY, Yum MS, Kim EH, Choi HW, Yoo HW, Ko TS

Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue. We report 2 cases of familial CCMs diagnosed with the CCM1...
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