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Improved immune responses and safety of foot-and-mouth disease vaccine containing immunostimulating components in pigs

Choi JH, You SH, Ko MK, Jo HE, Shin SH, Jo H, Lee MJ, Kim SM, Kim B, Lee JS, Park JH

Background: The quality of a vaccine depends strongly on the effects of the adjuvants applied simultaneously with the antigen in the vaccine. The adjuvants enhance the protective effect of the...
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New foot-and-mouth disease vaccine, O JC-R, induce complete protection to pigs against SEA topotype viruses occurred in South Korea, 2014–2015

Jo HE, Ko MK, Choi JH, Shin SH, Jo H, You SH, Lee MJ, Kim SM, Kim B, Park JH

Foot-and-mouth disease (FMD) is an acute epidemic that spreads rapidly among cattle and pigs. In 2014, in Korea, despite enforced vaccination, the type O Southeast Asia (SEA) topotype viruses (Mya-98...
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Prevalence and Risk Factors of Carbapenem-resistant Enterobacteriaceae Acquisition in an Emergency Intensive Care Unit in a Tertiary Hospital in Korea: a Case-Control Study

Kang JS, Yi J, Ko MK, Lee SO, Lee JE, Kim KH

BACKGROUND: Infections caused by carbapenem-resistant Enterobacteriaceae (CRE) are associated with high mortality rates and their treatment is difficult because treatment is limited to certain antibiotics, such as colistin and tigecycline....
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Deep Vein Thrombosis Due to Compression of Huge Hepatic Cyst Successfully Treated by Inferior Vena Cava Filter and Cyst Drainage

Ko MK, Kim T, Lee WH, Park SH, Choi JH, Shin M, Heo NY

An 88-year-old woman complained of right quadrant abdominal pain and severe edema in both legs. She had a history of pulmonary embolism one month ago. Abdomen CT showed a huge...
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Erratum: Correction of Author Information and Funding Source: Seroprevalence of Severe Fever with Thrombocytopenia Syndrome in Southeastern Korea, 2015

Kim KH, Ko MK, Kim N, Kim HH, Yi J

The authors regret that there were errors in the article. The errors were in one co-author's affiliation and funding source.
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Control of type O foot-and-mouth disease by vaccination in Korea, 2014–2015

Park JH, Tark D, Lee KN, Chun JE, Lee HS, Ko YJ, Kye SJ, Kim YJ, Oem JK, Ryoo S, Lim SB, Lee SY, Choi JH, Ko MK, You SH, Lee MH, Kim B

On December 3, 2014, a type O foot-and-mouth disease (FMD) outbreak began in Korea. Although vaccinations were administered, FMD cases increased steadily for five months, and reached 185 cases by...
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Severe Fever with Thrombocytopenia Syndrome Patients with Hemophagocytic Lymphohistiocytosis Retrospectively Identified in Korea, 2008–2013

Kim KH, Lee MJ, Ko MK, Lee EY, Yi J

The incidence of severe fever with thrombocytopenia syndrome (SFTS) has increased in Korea since a first report in 2013. We investigated whether SFTS existed before 2013 using real-time reverse transcription...
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Synergistic effect of ribavirin and vaccine for protection during early infection stage of foot-and-mouth disease

Choi JH, Jeong K, Kim SM, Ko MK, You SH, Lyoo YS, Kim B, Ku JM, Park JH

In many countries, vaccines are used for the prevention of foot-and-mouth disease (FMD). However, because there is no protection against FMD immediately after vaccination, research and development on antiviral agents...
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Immune responses in pigs and cattle vaccinated with half-volume foot-and-mouth disease vaccine

Park ME, You SH, Lee SY, Lee KN, Ko MK, Choi JH, Kim B, Lee JS, Park JH

With the current commercial foot-and-mouth disease vaccine, inoculating twice increases the formation of denatured meat due to granuloma or residual adjuvant at the injection site in pigs, resulting in economic...
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Seroprevalence of Severe Fever with Thrombocytopenia Syndrome in Southeastern Korea, 2015

Kim KH, Ko MK, Kim N, Kim HH, Yi J

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease characterized by fever, thrombocytopenia and diarrhea. SFTS was firstly reported in Korea in 2013 but its seroprevalence in the...
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Effects of the Enamel Erosion Caused by Certain Antipyretic and Analgesic Medicines for Children

Cheun SK, Jeong MJ, Ahn YS, Lee YJ, Ko MK, Jeong SJ, Lim DS

This study was conducted to provide basic understanding regarding possible enamel erosion by three kinds of fist-aid antipyretic and analgesic medicines over a period of time, with comparison and analysis...
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Novel foot-and-mouth disease virus in Korea, July-August 2014

Park JH, Tark D, Lee KN, Lee SY, Ko MK, Lee HS, Kim SM, Ko YJ, Seo MG, Chun JE, Lee MH, Kim B

Despite nation-wide immunization with O, A, and Asia 1 type vaccines in Republic of Korea, foot-and-mouth disease type O occurred again in July 2014 after three years and three months....
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Antigenic properties and virulence of foot-and-mouth disease virus rescued from full-length cDNA clone of serotype O, typical vaccine strain

Kim RH, Chu JQ, Park JN, Lee SY, Lee YJ, Ko MK, Hwang JH, Lee KN, Kim SM, Tark D, Ko YJ, Lee HS, Seo MG, Park ME, Kim B, Park JH

We cloned the full-length cDNA of O Manisa, the virus for vaccinating against foot-and-mouth disease. The antigenic properties of the virus recovered from the cDNA were similar to those of...
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Peripheral Vascular Leakage Findings of Asymptomatic Eyes Based on Fluorescein Angiography

Lee SH, Shin YU, Lee BR, Ko MK

  • KMID: 2338807
  • J Korean Ophthalmol Soc.
  • 2014 Jul;55(7):1017-1023.
PURPOSE: To report peripheral vascular retinal leakage findings of asymptomatic eyes based on fluorescein angiography, and investigate the associated factors. METHODS: Data were collected retrospectively from 47 subjects (94 eyes) and...
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A Case of Insulinoma with Hypoglycemic Encephalopathy

Kim KH, Kim ES, Park CS, Ko MK, Byun SS, Hong JM, Lee MY, Nam-Goong , Kim YI, Na YW, Choi HJ, Kwon JH

A 47-year-old male with recurrent abnormal behavior for ten years was referred to our clinic. He was diagnosed with insulinoma and cognitive dysfunction. Persistent hypoglycemia leads to a high risk...
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Utility of F-18 FDG-PET in Detecting Primary Aldosteronism in Patients with Bilateral Adrenal Incidentalomas

Ko MK, Park CS, Byun SS, Hong JM, Lee MY, Kim KH, Na YW, Choi HJ, Nam-Goong , Kim YI, Kim ES

In patients with primary aldosteronism who have bilateral adrenal incidentalomas, it is important to identify which adrenal gland is secreting excess aldosterone. Traditionally, adrenal vein sampling (AVS) has been performed...
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Clinical Characteristics of Occult HBV Infection and Impact on Treatment Response in Patients with Chronic Hepatitis C

Byun SS, Shin JW, Ko MK, Hong JM, Kim KH, Lee MY, Choi HJ, Jeong YK, Park BR, Park NH

  • KMID: 2264779
  • Korean J Med.
  • 2012 Dec;83(6):731-739.
BACKGROUND/AIMS: The prevalence of occult HBV infection (OBI) in patients with chronic hepatitis C (CHC) in Korea has not been reported. Additionally, it is unclear whether OBI influences treatment outcome...
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A Case of Dengue Fever with Maculopathy

Nam KW, Kim JE, Doo EY, Jung HM, Lee ES, Kim BS, Park JH, Min JY, Ko MK, Pai HJ

Dengue fever is transmitted principally by Aedes aegypti, which is not infested in Korea. Therefore, all Korean patients with dengue fever are imported cases from endemic areas such as Southeast...
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Prenatal diagnosis of trisomy 7 mosaicism with omphalocele in the first trimester of pregnancy

Ko MK, Cho IA, Lee JI, Park JK, Shin JK, Choi WJ, Lee SA, Lee JH, Paik WY

  • KMID: 2393149
  • Korean J Obstet Gynecol.
  • 2012 Oct;55(10):751-755.
The trisomy 7 is rare autosomal aneuploidy worldwide, which accounts for 4%-10% of all trisomies, and most of the cases are mosaicism. The partial trisomy 7 mosaicism demonstrates facial deformities,...
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A case of terminal deletion of chromosome 10p

Cho JH, Park JE, Ko MK, Kim EJ, Park JK, Lee SA, Lee JH, Paik WY

Chromosome 10p deletion (partial monosomy 10p) is rare chromosomal disorder. It was first reported in 1970. Since then, as far as we know, about 45 patients have been described. The...
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