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Immunohistochemical detection of GluA1 subunit of AMPA receptor in the rat nucleus accumbens following cocaine exposure

Cai WT, Han J, Kim WY, Kim JH

α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are differentially regulated in the nucleus accumbens (NAcc) of the brain after cocaine exposure. However, these results are supported only by biochemical and electrophysiological methods,...
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Association between body temperature measured at the emergency department with prognosis in septic shock patients

Choi JH, Park YS, Chung SP, Shin TG, Kim WY, Choi SH, Jo YH, Kang GH, Shin J, Lim TH, Han KS, Suh GJ, Korean Shock Society (KoSS) Investigators

  • KMID: 2506061
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):346-354.
Objective: Prior studies have explored the relationship between initial body temperature (BT) and mortality in patients with sepsis in the emergency department (ED). However, there has been no study on...
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Antioxidant and hepatoprotective effects of Korean ginseng extract GS-KG9 in a D-galactosamine-induced liver damage animal model

Jo YH, Lee H, Oh MH, Lee GH, Lee YJ, Lee JS, Kim MJ, Kim WY, Kim JS, Yoo DS, Cho SW, Cha SW, Pyo MK

BACKGROUND/OBJECTIVES: This study was designed to investigate the improvement effect of white ginseng extract (GS-KG9) on D-galactosamine (Ga1N)-induced oxidative stress and liver injury. SUBJECTS/METHODS: Sixty Sprague-Dawley rats were divided into 6...
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Cancer patients with neutropenic septic shock: etiology and antimicrobial resistance

Jung SM, Kim YJ, Ryoo SM, Sohn CH, Seo DW, Lim KS, Kim WY

Background/Aims: Among patients with febrile neutropenia that developed after chemotherapy, high-risk patients, such as those having clinical instability or Multinational Association of Supportive Care in Cancer score of < 21,...
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Vasospasm-related Sudden Cardiac Death Has Outcomes Comparable with Coronary Stenosis in Out-of-Hospital Cardiac Arrest

Lee DH, Lee BK, Kim YH, Park YS, Sim MS, Kim SJ, Oh SH, Lee DH, Kim YJ, Kim WY

Background: Characteristics of coronary vasospasm-related sudden cardiac death are not well understood. We aimed to compare the characteristics and clinical outcomes between coronary vasospasm and stenosis, in out-of-hospital cardiac arrest...
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Comparison between transumbilical and transvaginal morcellation of a large uterus during single-port-access total laparoscopic hysterectomy

Oh SJ, Lee SY, Kim WY, Kang J, Han KH, Lee SH, Park JS

Objective To compare the perioperative outcomes of transumbilical morcellation (TUM) and transvaginal morcellation (TVM) of a large uterus (≥500 g) during single-port-access total laparoscopic hysterectomy (SPA-TLH). Methods A total of 57 patients who underwent...
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Research for improvement of the national evaluation program for emergency medical center in Korea

Han KS, Kim WY, Kim SJ, Jeong J, Kang H, Lee C, Lee SW

In Korea, the national evaluation program for emergency medical centers (EMCs) was introduced in 2003. EMCs in Korea have three levels of emergency centers including regional emergency centers, local emergency...
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Survey of physicians' views on the clinical implementation of pharmacogenomics-based personalized therapy

Kim WY, Kim HS, Oh M, Shin JG

Despite quantitative increases and qualitative advances in pharmacogenomics (PGx) research, the clinical implementation of PGx-based personalized therapy has still been limited. The objective of this study was to assess physicians'...
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Evaluation of the Toxicity of Sugammadex in Zebrafish Larvae

Kim WY, Kim YH, Lee JY, Kim JH, Min TJ

BACKGROUND: Sugammadex is a new neuromuscular blockade reversal agent. Recently, it has been used in patients under general anesthesia. However, sugammadex could be toxic to fetuses and pediatric patients under...
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The Effective Weight Loss Therapy for Successful Weight Loss and the Relationship between Successful Weight Loss and Mental Health: The 2016, 7th Korean National Health and Nutrition Examination Survey

Bae HW, Kim WY

Background: This study was conducted to evaluate the effect of a weight loss method in individuals who successfully lost weight and determine the mental health problems that might have occurred...
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Yearly trend of milk intake in Korean children and adolescents and their nutritional status by the milk intake level using 2007–2015 Korea National Health and Nutrition Examination Survey

Kim Wy, Ha AW, Lee JH, Kim SH

Purpose This study examined the yearly trend of milk consumption and the nutritional status of subjects aged 6–18 years using the 2007–2015 Korea National Health and Nutrition Examination Survey data. Methods Milk and...
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Big Data-Driven Approach for Health Inequalities in Foreign Patients with Injuries Visiting Emergency Rooms

Kang JY, Kwon J, Sohn CH, Kim YJ, Lim HW, Lee SJ, Kim WY, Kim N, Seo DW

OBJECTIVES: Foreign patients are more likely to receive inappropriate health service in the emergency room. This study aimed to investigate whether there is health inequality between foreigners and natives who...
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Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core

Kim WY, Cai WT, Jang JK, Kim JH

The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases...
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Serum Cadmium Level Is Positively Associated with Unruptured Intracranial Aneurysm Incidence

Yoon BN, Lee JB, Jin GH, Kim WY

BACKGROUND: Cadmium is a toxic element in cigarette smoke associated with ischemic vascular disease. Its association with cerebral aneurysm is unknown. METHODS: We retrospectively analyzed the medical records of patients with...
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Extended Use of Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: A Retrospective Multicenter Study

Kim WY, Park S, Kim HJ, Baek MS, Chung CR, Park SH, Kang BJ, Oh JY, Cho WH, Sim YS, Cho YJ, Park S, Kim JH, Hong SB

BACKGROUND: Beyond its current function as a rescue therapy in acute respiratory distress syndrome (ARDS), extracorporeal membrane oxygenation (ECMO) may be applied in ARDS patients with less severe hypoxemia to...
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Intrapelvic Migration of the Lag Screw with Wedge Wing from Dyna Locking Trochanteric Nail: A Case Report and Literature Review

Kim YW, Kim WY, Kim KJ, Lee SW

The intrapelvic migration of cervicocephalic lag screws is a rare complication after intertrochanteric fracture synthesis with an intramedullary nail. Only 15 cases of intrapelvic penetration by three different instrument systems...
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Acute fulminant myocarditis following influenza vaccination requiring extracorporeal membrane oxygenation

Kim YJ, Bae JI, Ryoo SM, Kim WY

The inactivated influenza vaccination is generally safe with mostly mild side effects. We report a rare but fatal adverse event following influenza vaccination. A previously healthy 27-year-old woman who received...
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Relationship between low hemoglobin levels and mortality in patients with septic shock

Jung SM, Kim YJ, Ryoo SM, Kim WY

BACKGROUND: Hemoglobin levels are a critical parameter for oxygen delivery in patients with shock. On comparing target hemoglobin levels upon transfusion initiation, the correlation between the severity of decrease in...
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Utility of the early lactate area score as a prognostic marker for septic shock patients in the emergency department

Yu G, Yoo SJ, Lee SH, Kim JS, Jung S, Kim YJ, Kim WY, Ryoo SM

BACKGROUND: The current Surviving Sepsis Campaign guidelines recommend the remeasurement of lactate levels if the initial lactate level is elevated; however, the prognostic value of lactate kinetics is limited and...
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New Termination-of-Resuscitation Models and Prognostication in Out-of-Hospital Cardiac Arrest Using Electrocardiogram Rhythms Documented in the Field and the Emergency Department

Lee DE, Lee MJ, Ahn JY, Ryoo HW, Park J, Kim WY, Shin SD, Hwang SO, on behalf of the Korean Cardiac Arrest Research Consortium (KoCARC)

BACKGROUND: Electrocardiogram (ECG) rhythms, particularly shockable rhythms, are crucial for planning cardiac arrest treatment. There are varying opinions regarding treatment guidelines depending on ECG rhythm types and documentation times within...
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