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Elevated Serum Leptin Receptor and Insulin-like Growth Factor-1 Levels and High Levels of Leptin Receptor Expression in Acanthosis Nigricans Patients: Serologic and Histopathologic Analyses

Kim WO, Kim HW, Joe HJ, Ryoo YW, Jung HR, Kim SA

  • KMID: 2506584
  • Korean J Dermatol.
  • 2020 Sep;58(8):530-536.
Background: Acanthosis nigricans is characterized by a velvety thickening of the epidermis accompanied by different degrees of hyperpigmentation, and known to be linked to obesity and insulin resistance. Objective: We aimed...
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Higher Lactate Level and Lactate-to-Pyruvate Ratio in Autism Spectrum Disorder

Oh M, Kim SA, Yoo HJ

  • KMID: 2506535
  • Exp Neurobiol.
  • 2020 Aug;29(4):314-322.
  • doi: 10.5607/en20030
Mitochondrial dysfunction is considered one of the pathophysiological mechanisms of autism spectrum disorder (ASD). However, previous studies of biomarkers associated with mitochondrial dysfunction in ASD have revealed inconsistent results. The...
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Effects of BeHaS Program on Health Behavior, Physiologic Index and Self-Esteem of the Elderly Living Alone with Metabolic Syndrome Based on Community Based Participatory Research

Kim JI, Kim SA, Park K, Kim J, Lee L, Choi SW, Ku BJ

Purpose: This study aimed to determine the effects of a 12-week metabolic syndrome BeHaS (Be Happy and Strong) program in elderly people with metabolic syndrome living alone, based on a...
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Nicolau Syndrome after Intramuscular Aminoglycoside Injection

Kim JH, Kim JH, Kim SA, Baek SE, Oh DY

Nicolau syndrome is a rare iatrogenic adverse reaction caused by intramuscular injection of various medications. The clinical features include pain, erythematous swelling, infection, and local ischemic necrosis, but the pathogenesis...
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Ultraviolet B Downregulated Aquaporin 1 Expression via the MEK/ERK pathway in the Dermal Fibroblasts

Kim WO, Kim SA, Jung YA, Suh SI, Ryoo YW

Background: Aquaporin 1 (AQP1) is a transmembrane channel protein that allows rapid transposition of water and gases, in recent discoveries of AQP1 function involve cell proliferation, differentiation, wound healing, inflammation...
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Urinary Concentration Defect and Renal Glycosuria in Cyclosporine-treated Rats

Lee JH, Kim SA, Jo CH, Lee CH, Kim GH

Background: Urinary concentration impairment is a major feature of cyclosporine nephrotoxicity. Methods: We explored two possible mechanisms that may underlie cyclosporineinduced polyuria; water, and/or osmotic diuresis. Cyclosporine was subcutaneously injected to...
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The Association of Relative Handgrip Strength with Impaired Fasting Glucose among Koreans Aged more than 20 Years Old

Kim SA, Choi EY, Park EW, Cheong YS

Background: The prevalence of impaired fasting glucose (IFG) in Korea is increasing. Few studies have investigated the relationship between handgrip strength (HGS) and type 2 diabetes among Koreans; however, no...
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Validation of the Korean version of the StandardizedCosmesis and Health Nasal Outcomes Survey

Choi WR, Kim SA, Kim SH, Jang YJ

Background and Objectives The 10-item Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) is a recently developed questionnaire for assessing both nasal obstruction and nasal cosmetic satisfaction. It is widely...
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Complete denture rehabilitation of edentulous patient with severe alveolar bone resorption andcondyle fracture using gothic arch tracing and closed mouth impression technique: A case report

Choi IH, Kim SA, Kim NH, Lee YS

It is essential to record maxillomandibular relationship accurately for the harmony of esthetic and function in complete denture. Gothic arch tracing visually demonstrates the movement of the mandible, and is useful...
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Expression of Human Herpes Virus 6, 7, Epstein-Barr Virus and Cytomegalovirus in Patients with Diverse Adverse Cutaneous Reactions to Drug

Ryoo YW, Lee JB, Kim WO, Kim SA

No abstract available.
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The pharmacology course for preclinical students using team-based learning

Kim DH, Lee JH, Kim SA

Purpose: A pharmacology course in undergraduate medical education aims to enable students to cultivate the ability of applying drugs in the clinical context using basic scientific knowledge. Although team-based learning...
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Can Current Recommendations on Sun Exposure Sufficiently Increase Serum Vitamin D Level?: One-Month Randomized Clinical Trial

Lee YM, Kim SA, Lee DH

BACKGROUND: Lack of sunlight exposure is the primary reason for the worldwide epidemic of vitamin D deficiency. Although recommended sunlight exposure guidelines exist, there is no evidence regarding whether current...
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The association of potassium intake with bone mineral density and the prevalence of osteoporosis among older Korean adults

Ha J, Kim SA, Lim K, Shin S

BACKGROUND/OBJECTIVES: Osteoporosis is characterized by low bone mass and results in vulnerability to fracture. Calcium and vitamin D are known to play an important role in bone health. Recently, potassium...
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Diosmetin and Its Glycoside, Diosmin, Improve Atopic DermatitisLike Lesions in 2,4-Dinitrochlorobenzene-Induced Murine Models

Park Sa, Bong SK, Lee JW, Park NJ, Choi Y, Kim SM, Yang MH, Kim YK, Kim SN

Naturally derived diosmetin and its glycoside diosmin are known to be effective in treating inflammatory disease. This study was performed to determine whether diosmin and diosmetin have the effect of...
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Full mouth rehabilitation with vertical increase in patient with severe tooth wear using monolithic zirconia prosthetic restoration

Bang JW, Kim SA, Lim SY, Lee YS

Gradual teeth wear is normal physiological progress, severe tooth wear can causes dysfunction, occlusal plane disharmony and esthetic problems. If additional space is needed for prosthetic restoration due to severe...
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Evolution of Interferon-Gamma Release Assay Results and Submillisievert Chest CT Findings among Close Contacts of Active Pulmonary Tuberculosis Patients

Yoon S, Mihn DC, Song JH, Kim SA, Yim JJ

Background: Latent tuberculosis (TB) infection among TB contacts is diagnosed using plain chest radiography and interferon-gamma release assays (IGRAs). However, plain chest radiographs often miss active TB, and the results...
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Can Habitual Exercise Help Reduce Serum Concentrations of Lipophilic Chemical Mixtures? Association between Physical Activity and Persistent Organic Pollutants

Lee YM, Shin JY, Kim SA, Jacobs Jr. DR, Lee DH

Background: Low-dose persistent organic pollutants (POPs), especially organochlorine pesticides (OCPs), have emerged as a new risk factor of many chronic diseases. As serum concentrations of POPs in humans are mainly...
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Effect of Dialysis on Aryl Hydrocarbon Receptor Transactivating Activity in Patients with Chronic Kidney Disease

Kim JT, Kim SH, Min HK, Jeon SJ, Sung SA, Park WH, Lee HK, Choi HS, Pak YK, Lee SY

PURPOSE: Elevated aryl hydrocarbon receptor (AhR) transactivating (AHRT) activity and uremia in chronic kidney disease (CKD) may interact with each other, further complicating the disease course. In this study, we...
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Risk Factors for Metachronous Recurrence after Endoscopic Submucosal Dissection of a Gastric Neoplasm

Choe AR, Shim KN, Kim TO, Kim SY, Lim J, Tae CH, Moon CM, Kim SE, Jung HK, Jung SA

BACKGROUND/AIMS: Although endoscopic submucosal dissection (ESD) is an accepted treatment method for gastric neoplasm worldwide, metachronous recurrence often occurs. Here, we evaluated the risk factors for metachronous recurrence after ESD...
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Proposal of a New TNM Classification for Gastric Cancer: Focusing on pN3b and Cytology-Positive (CY1) Disease

Kim SH, Lee HJ, Park JH, Choi JH, Park SH, Choe HN, Oh SY, Suh YS, Kong SH, Park DJ, Yang HK

PURPOSE: Gastric cancer with lymph node metastasis (LNM) more than 15 (N3b) was defined as stage IV until the 6th AJCC system. However, it has been reclassified as a localized...
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