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Apoptotic activity of demethoxycurcumin in MG-63 human osteosarcoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Chun HS, Yu SK, Kim HJ, Kim CS, Kim DK

Demethoxycurcumin (DMC), which is a curcuminoid found in turmeric, has anti-proliferative effects on cancer cells. However, the effect of DMC on osteosarcoma has not been established. The aim of this...
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Alpha-lipoic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced cell injury by inhibiting autophagy and apoptosis

Kang KR, Kim JS, Kim TH, Seo JY, Lim H, Park JH, Yang KY, Yu SK, Kim HJ, Kim CS, Chun HS, Lee DS, Park JC, Kim DK

Alpha-lipoic acid (ALA) is a naturally occurring antioxidant and has been previously used to treat diabetes and cardiovascular disease. However, the autophagy effects of ALA against oxidative stress-induced dopaminergic neuronal...
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Impact of the COVID-19 Outbreak on Trends in Emergency Department Utilization in Children: a Multicenter Retrospective Observational Study in Seoul Metropolitan Area, Korea

Choi DH, Jung JY, Suh D, Choi JY, Lee SU, Choi YJ, Kwak YH, Kim DK

Background: Understanding the changes in emergency department (ED) visit patterns during the coronavirus disease 2019 (COVID-19) outbreak is important for effectively operating EDs during the pandemic. We aimed to analyze...
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The Impact of Erosive Reflux Esophagitis on the Decline of Lung Function in the General Population

Kang HR, Lee YJ, Lee HY, Park TY, Lee JK, Heo EY, Chung HS, Choi SH, Kim DK

Background: The impact of reflux esophagitis on the decline of lung function has been rarely reported. This study was performed to evaluate the association between erosive reflux esophagitis and lung...
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Clinical implication and risk factor of pneumonia development in mild coronavirus disease 2019 patients

Lee HW, Yoon SY, Lee JK, Park TY, Kim DK, Chung HS, Heo EY

Background/Aims Although a majority of coronavirus disease 2019 (COVID-19) cases were characterized as mild, data assessing the development of pneumonia in mild COVID-19 patients are limited. We aimed to examine the...
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Studies on Signal Transduction Mechanism of Alcohol-induced Neuronal Cell Death and Protective Effect

Lee D, Kim S, Kim K, Lee W, Kim D, Kim K, Jung H, Lee S

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Magnesium Hydride Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia

Lee MJ, Lee JH, Kim DK, Lee NS, Jeong YG, Jeong JH, Park JH, Yoo YC, Han SY

Abstract : Reactive oxygen species (ROS)-mediated oxidative stress plays a key role in the pathogenesis of central nervous system diseases, including vascular dementia (VaD). Thus, scientific attention has been given...
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Inhibition of cell growth and induction of apoptosis by acacetin in FaDu human pharyngeal carcinoma cells

Kang KR, Kim JS, Kim TH, Seo JY, Park JH, Lim JW, Yu SK, Kim HJ, Shin SH, Park BR, Kim CS, Kim DK

Acacetin, which is present in damiana (Turnera diffusa) and black locust (Robinia pseudoacacia), has several pharmacologic activities such as antioxidant, anti-inflammatory, and anti-proliferative effects on cancer cells. However, the effect...
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Impact of gender on chronic obstructive pulmonary disease outcomes: a propensity scorematched analysis of a prospective cohort study

Cho J, Lee CH, Kim DK, Hwang HG, Kim YI, Choi HS, Park JW, Yoo KH, Jung KS, Lee SD

Background/Aims: Despite increasing awareness of the burden of chronic obstructive pulmonary disease (COPD) in women, knowledge regarding gender differences in COPD outcomes is limited. Therefore, we aimed to evaluate whether...
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Business Cycle and Occupational Accidents in Korea

Kim DK, Park S

Background: Occupational accidents occur for a variety of reasons, such as unsafe behaviors of workers and insufficient safety equipment at the workplace, but there are also various economic and social...
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A Pilot Study on the Effect of Cannabis Extract on Weight Loss in Diet-induced Obese Mice

Jang YJ, Lim SW, Woo SY, Kim SY, Kim DK

Objectives This study aimed to investigate the pharmacological effect of cannabis extract on weight loss in diet-induced obese mice. Methods A total of 12 C57BL/6 male mice (Orient Bio), aged 6...
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Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: Incorporating Considerations of Resources Use into Grading Recommendations’ (A Secondary Publication)

Kim HW, Jung JH, Kim DK, Kang HW, Ku JY, Jung HJ, Hwang EC, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

This article is the fifth translation of a GRADE series published in the BMJ for incorporating the considerations of resources use into grading recommendations. Clinical recommendations inevitably involve judgments about the...
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Veno-arterial extracorporeal membrane oxygenation may be useful in critically ill COVID-19 patients with suspected cardiac injury

Heo E, Oh SJ, Lee HW, Lee JK, Kim DK, Park SW

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The First Finding of the Lichen Solorina saccata at an Algific Talus Slope in Korea

Park JS, Kim DK, Kim CS, Oh S, Kim KH, Oh SO

An algific talus slope is composed of broken rocks with vents connected to an ice cave, releasing cool air in summer and relatively warmer air in winter to maintain a...
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KSNR Clinical Consensus Statements: Rehabilitation of Patients with Parkinson's Disease

KSNR PD Writing Group, Kim DY, Oh HM, Bok SK, Chang WH, Choi Y, Chun MH, Han SJ, Han TR, Jee S, Jung SH, Jung HY, Jung TD, Kim MW, Kim EJ, Kim HS, Kim YH, Kim Y, Kim DY, Kim DY, Kim DK, Ko SH, Ko MH, Lee JK, Lee J, Lee SJ, Lee SG, Lim SH, Oh BM, Paik NJ, Park KD, Park SW, Park GY, Park JH, Park YG, Pyun SB, Ryu B, Seo HG, Shin YI, Sohn MK, Yang SN, Yoo SD, Yoo WK

Clinical consensus statements (CCSs) aim to improve care for patients with Parkinson's disease (PD) and reduce the variability of rehabilitation methods in clinical practice. A literature search was conducted to...
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Carbon monoxide–releasing molecule-3: Amelioration of renal ischemia reperfusion injury in a rat model

Kim DK, Shin SJ, Lee J, Park SY, Kim YT, Choi HY, Yoon YE, Moon HS

Purpose: Despite the role of carbon monoxide in ameliorating ischemia-reperfusion injury (IRI), its use in the clinical setting is restricted owing to its toxicity. Herein, we investigated the in vivo...
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Performances of serum creatinine, C-reactive protein and white blood cell to predict urinary tract infection in febrile children younger than 24 months of age

Lee HS, Kwak YH, Park JW, Kim DK, Lee SU

Purpose: Differentiation of urinary tract infection (UTI) from viral infection is a critical challenge in febrile children in emergency departments (EDs). This study aimed to assess the predicting performances of...
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Reduced risk for chronic kidney disease after recovery from metabolic syndrome: A nationwide populationbased study

Park S, Lee S, Kim Y, Lee Y, Kang MW, Han K, Lee H, Lee JP, Joo KW, Lim CS, Kim YS, Kim DK

Background: Metabolic syndrome (MetS) is linked to various chronic comorbidities, including chronic kidney disease (CKD). However, few large studies have addressed whether recovery from MetS is associated with reduction in...
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Korean clinical practice guidelines for preventing transmission of coronavirus disease 2019 (COVID-19) in hemodialysis facilities

Park HC, Kim DH, Yoo KD, Kim YG, Lee SH, Yoon HE, Kim DK, Kim SN, Kim MS, Jung YC, Kim YS, Lee YK, The Korean Society of Nephrology COVID-19 Task Force Team

Coronavirus disease 2019 (COVID-19) is a highly contagious viral disease that is caused by the novel virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). COVID-19 has become pandemic since December 2019,...
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A Case of Nasofrontal Dermoid Cyst Via Transcollumelar Approach

Lee KH, Lee SM, Kim SW, Park KJ, Kim DK

The midline nasal dermoid cysts are rare congenital neoplasms, which are diagnosed frequently in childhood. Masses are often noticeable at birth gaining size over time with recurrent infections and usually...
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