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Stratification of Nuclear Homogeneous Patterns on HEp-2 Cells Based on Neutrophil Nuclear Staining

Won DI, Park J, Kim BS, Kim CE, Yoon HS, Jung JS

Antinuclear antibody (ANA) testing is used to diagnose systemic autoimmune rheumatic disease (SARD). Nuclear homogeneous patterns on ANA-HEp-2 cells can result from anti-double-stranded DNA (dsDNA), anti-nucleosome, anti-histone, anti-Scl-70, or anti-dense...
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Suicidality and Related Psychopathology across Different Stages of Schizophrenia

Joh E, Park K, Lee DK, Lee H, Kim CE, Ryu S

Objectives: This study aimed to investigate suicidal behaviors and the related psychopathology across the different stages of schizophrenia. Methods: We recruited 131 patients with schizophrenia and categorized them into two groups,...
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Ketamine-Induced Behavioral Effects Across Different Sub-AnestheticDose Ranges in Adolescent and Adult Mice

Choi HJ, Im SJ, Park HR, Lee SM, Kim CE, Ryu S

ObjectivesZZKetamine has been reported to have antidepressant effects or psychotomimetic effects. The aim of this study was to investigate the behavioral effects of ketamine treatment at various sub-anesthetic doses in adolescent...
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Semantic Network Analysis of Iussues Related to Mental Illness in Korea Media: Focusing on the Five Major Media from 2016 to 2018

Park SJ, Shin NR, Kim SH, Park SB, Kim CE

OBJECTIVES: This study examined the trend of press reports on mental illness in Korea to help set a desirable direction for future press reports on the subject. METHODS: This study adopted...
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Multiplexed Processing of Vibrotactile Information in the Mouse Primary Somatosensory Cortex

Kim YR, Kim CE, Yoon H, Kim SK, Kim SJ

  • KMID: 2510505
  • Exp Neurobiol.
  • 2020 Dec;29(6):425-432.
  • doi: 10.5607/en20041
The primary somatosensory (S1) cortex plays a key role in distinguishing different sensory stimuli. Vibrotactile touch information is conveyed from the periphery to the S1 cortex through three major classes...
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Long-term Effects of Aripiprazole Treatment during Adolescence on Cognitive Function and Dopamine D2 Receptor Expression in Neurodevelopmentally Normal Rats

Choi HJ, Im SJ, Park HR, Park S, Kim CE, Ryu S

OBJECTIVE: This study aimed to investigate the long-term effects of aripiprazole treatment during adolescence on behavior, cognitive function, and dopamine D2 receptor (D2R) expression in adult rats. METHODS: Adolescent male Sprague-Dawley...
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Detection of Suicide Attempters among Suicide Ideators Using Machine Learning

Ryu S, Lee H, Lee DK, Kim SW, Kim CE

OBJECTIVE: We aimed to develop predictive models to identify suicide attempters among individuals with suicide ideation using a machine learning algorithm. METHODS: Among 35,116 individuals aged over 19 years from the...
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Mental Health Literacy of Autism Spectrum Disorder in Korea: Recognition, Etiology, Treatment

Rim SJ, Park S, Lee Y, Kim CE

OBJECTIVE: The objective of this study was to investigate the Korean public’s recognition of autism spectrum disorder (ASD), revealing underlying factors regarding perception relative to etiology and treatment of ASD,...
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Functional Disabilities Evaluated using World Health Organization Disability Assessment Schedule 2.0 in Patients with Chronic Schizophrenia and Its Related Factors

Park K, Lee DK, Lee H, Kim CE, Ryu S

OBJECTIVES: This study examined the functional disabilities of patients with chronic schizophrenia using WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) and its related factors. METHODS: The subjects consisted of 86 patients...
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Physical Activity of Patients with Chronic Schizophrenia and Related Clinical Factors

Lee SH, Kim G, Kim CE, Ryu S

OBJECTIVE: This study aimed to investigate clinical factors contributing to the low physical activity (PA) of patients with chronic schizophrenia. METHODS: PA was measured in 50 outpatients with chronic schizophrenia using...
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The effect of µ-opioid receptor activation on GABAergic neurons in the spinal dorsal horn

Kim YR, Shim HG, Kim CE, Kim SJ

The superficial dorsal horn of the spinal cord plays an important role in pain transmission and opioid activity. Several studies have demonstrated that opioids modulate pain transmission, and the activation...
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An association between diet quality index for Koreans (DQI-K) and total mortality in Health Examinees Gem (HEXA-G) study

Lim J, Lee Y, Shin S, Lee HW, Kim CE, Lee JK, Lee SA, Kang D

BACKGROUND/OBJECTIVES: Diet quality scores or indices, based on dietary guidelines, are used to summarize dietary intake into a single numeric variable. The aim of this study was to examine the...
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The Prevalence of Chronic Physical Diseases Comorbid with Depression among Different Sex and Age Groups in South Korea: A Population-Based Study, 2007–2014

Park SJ, Hong S, Jang H, Jang JW, Yuk B, Kim CE, Park S

OBJECTIVE: People with depression often suffer from comorbid, chronic physical diseases. Little is known about how demographic characteristics such as age and sex influence the prevalence of chronic physical diseases...
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A Preliminary Study to Determine Comprehensive Research and Development Plans for Promoting Mental Health Services

Kim CE, Ko YM, Lee SU, Choi S, Han K, Park SJ, Jo M, Park YK, Lee HY, Park S

OBJECTIVES: The aim of this study was to analyze research and development projects in mental health services in Korea, using priority evaluation of mental health promotion policies to determine direction...
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Operation Status and Improvement Plan of Continuing Hospitalization Judgement System in Mental Health Review Board

Park SJ, Nam YY, Hwang TY, Joe KH, Jun JY, Kim EJ, Kim CE

BACKGROUND: The recent revision of South Korea's Mental Health Law emphasizes the role of the Mental Health Review Board. For this study, we examined the current status of continuing hospitalization...
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The Development of the Mission · Vision · Core Values for Korean NeuroPsychiatric Association

Han C, Lee K, Jung HY, Lee KJ, Kim CE

Awareness of public mental health has increased due to drastic changes in society, and issues concerning the rights of mentally ill patients have emerged. The Korean NeuroPsychiatric Association (KNPA) has...
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Comparison of Hematologic Variability between Clozapine Monotherapy and Augmentation Therapy with Atypical Antipsychotics for Schizophrenia: Results from a 6-Month Retrospective Follow-Up Study

Shin J, Oh SM, Kim WH, Bae JN, Lee JS, Kim CE, Kim JH

OBJECTIVES: Clozapine is an antipsychotic agent commonly prescribed in patients with treatment-resistant schizophrenia. A drawback of using clozapine is risk of hematologic side effects ranging from mild neutropenia to fatal...
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Reason for Clozapine Discontinuation

Cho JW, Kim WH, Shin JH, Kim JH, Lee JS, Bae JN, Kim CE

OBJECTIVES: Approximately 30% of individuals diagnosed with schizophrenia suffer from treatment-resistant schizophrenia. Clozapine is underutilized in the management of treatment-resistant schizophrenia. To understand contributing factors, we analyzed the time course...
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Factors Affecting Quality of Life and Family Burden among the Families of Patients with Schizophrenia

Maeng SR, Kim WH, Kim JH, Bae JN, Lee JS, Kim CE

OBJECTIVES: Study aimed to identify factors that may affect family burden and quality of life (QOL) of primary caregivers in schizophrenia family. METHODS: Among outpatients with schizophrenia undergoing treatment at the...
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Therapeutic Dose Range of Valproate-Induced Hyperammonemic Encephalopathy: A Case Report

Maeng SR, Roh JH, Kim CE

We report a case of a 34-year-old woman who was in temporary delirium and hyperammonemia during treatment of bipolar affective disorder with valproate. Patient showed delirium after 20 days of...
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