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Minimally Invasive Gastric Electrical Stimulation Using a Newly Developed Wireless Gastrostimulator: A Pilot Animal Study

Kim SH, Kim HB, Chun HJ, Choi HS, Kim ES, Keum B, Seo YS, Jeen YT, Lee HS, Um SH, Kim CD

  • KMID: 2504010
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):410-416.
  • doi: 10.5056/jnm20063
Background/Aims Gastric electrical stimulation (GES) is a feasible modality for the treatment of gastroparesis; however, the presently available device requires invasive surgical implantation for long-term stimulation and repeated surgical procedure...
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Combination therapy with cilostazol, aripiprazole, and donepezil protects neuronal cells from β-amyloid neurotoxicity through synergistically enhanced SIRT1 expression

Heo HJ, Park SY, Lee YS, Shin HK, Hong KW, Kim CD

Alzheimer’s disease (AD) is a multi-faceted neurodegenerative disease. Thus, current therapeutic strategies require multitarget-drug combinations to treat or prevent the disease. At the present time, single drugs have proven to...
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Natural soluble human leukocyte antigen class I in donor serum neutralizes donor-specific HLA alloantibodies in recipient serum

Won DI, Lee NY, Lim JH, Han YS, Kim CD, Huh S

Background Human leukocyte antigen (HLA) molecules are cell-bound but can be identified in a soluble form. These soluble HLA (sHLA) molecules have an immunomodulatory function. We investigated whether natural sHLA...
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Mycophenolic Acid Trough Concentration and Dose Are Associated with Hematologic Abnormalities but Not Rejection in Kidney Transplant Recipients

Jung HY, Lee S, Jeon Y, Choi JY, Cho JH, Park SH, Kim YL, Kim HK, Huh S, Won DI, Kim CD

Background: Little is known regarding the safe fixed dose of mycophenolic acid (MPA) for preventing biopsy-proven acute rejection (BPAR) in kidney transplant recipients (KTRs). We investigated the correlation of MPA...
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Novel Mechanism of Action of Dutasteride for Inducing Hair Growth in Patients with Female-Pattern Hair Loss

Kim S, Hwang YL, Yim SH, Hong D, Choi CW, Jung KE, Seo YJ, Kim CD, Shin J, Lee Y

  • KMID: 2502820
  • Korean J Dermatol.
  • 2020 May;58(4):231-238.
Background: Female-pattern hair loss (FPHL) is a common hair loss disorder in women. The various treatments include topical minoxidil and 17α-estradiol, as well as oral anti-androgens. However, the clinical efficacy...
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Patterns in renal diseases diagnosed by kidney biopsy: A single-center experience

Yim T, Kim SU, Park S, Lim JH, Jung HY, Cho JH, Kim CD, Kim YL, Han MH, Kim YJ, Choi JY, Park SH

Background: The worldwide incidence of renal disease diagnosed by a kidney biopsy varies with age, race, sex, and region. Owing to a lack of studies and limited research resources for...
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Possible Role of Lysine Demethylase 2A in the Pathophysiology of Psoriasis

Kim DH, Choi MR, Lee JK, Hong DK, Jung KE, Choi CW, Lee Y, Kim CD, Seo YJ, Lee JH

Background Psoriasis is a common chronic inflammatory skin disease. The development of psoriasis is dependent on many intercellular events such as innate immunity and T cell-mediated inflammation. Furthermore, genetic factors are...
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Evaluation of Treatment Response after Endoscopic Variceal Obturation with Abdominal Computed Tomography

Lee HA, Goh HG, Kim TH, Lee YS, Suh SJ, Jung YK, Choi HS, Kim ES, Kim JH, An H, Seo YS, Yim HJ, Cho SB, Jeen YT, Yeon JE, Chun HJ, Byun KS, Um SH, Kim CD

Backgrounds/Aims: Rebleeding of gastric varices (GVs) after endoscopic variceal obturation (EVO) can be fatal. This study was performed to evaluate the usefulness of computed tomography (CT) for the prediction of...
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Outcomes of open heart surgery in patients with end-stage renal disease

Park JH, Lim JH, Lee KH, Jung HY, Choi JY, Cho JH, Kim CD, Kim YL, Jung H, Kim GJ, Park SH

BACKGROUND: Cardiovascular diseases of chronic dialysis patients are often undertreated because of their higher surgical risk. This study aimed to assess mortality and morbidity after open heart surgery in chronic...
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Clinical value of an adenosine triphosphate-based chemotherapy response assay in resectable stage III colorectal cancer

Kim CD, Kim SH, Jung SH, Kim JH

PURPOSE: ATP-based chemotherapy response assay (ATP-CRA) is a well-documented and validated technology that can individualize chemotherapy. This study was undertaken to assess the usefulness of ATP-CRA in advanced colorectal cancer...
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Clinical Relevance for Serum Cold-Inducible RNA-Binding Protein Level in Alopecia Areata

Shin JM, Ko JW, Kwon IS, Choi JW, Hong D, Lee JH, Seo YJ, Kim CD, Lee JH, Lee Y, Park KD

BACKGROUND: Alopecia areata (AA), a chronic, relapsing hair-loss disorder, is considered to be a T-cell-mediated autoimmune disease. Cold-inducible RNA-binding protein (CIRP) belongs to a family of cold-shock proteins that respond...
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Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD

BACKGROUND: Sebocytes are the major cells of sebaceous gland. The essential role of sebocytes is the production of sebum, a specific lipid mixture, that covers the body surface and provides...
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Inhibition of Poly(I:C)-Induced Inflammation by Salvianolic Acid A in Skin Keratinocytes

Zhang QL, Jiang RH, Li XM, Ko JW, Kim CD, Zhu MJ, Lee JH

BACKGROUND: Skin keratinocytes participate actively in inducing immune responses when external pathogens are introduced, thereby contributing to elimination of pathogens. However, in condition where the excessive inflammation is occurred, chronic...
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Comparison of Transplant Outcomes for Low-level and Standard-level Tacrolimus at Different Time Points after Kidney Transplantation

Jung HY, Cho SY, Choi JY, Cho JH, Park SH, Kim YL, Kim HK, Huh S, Won DI, Kim CD

BACKGROUND: Optimal tacrolimus (TAC) trough levels for different periods after kidney transplantation (KT) has not been definitely established. This study aimed to investigate transplant outcomes of low-level (LL) and standard-level...
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Adiponectin Attenuates the Inflammation in Atopic Dermatitis-Like Reconstructed Human Epidermis

Seo HS, Seong KH, Kim CD, Seo SJ, Park BC, Kim MH, Hong SP

BACKGROUND: Atopic dermatitis (AD) is a chronic disorder, with a vicious cycle of repetitive inflammation and deterioration of the epidermal barrier function. Adiponectin, an adipokine, has anti-inflammatory effects on various...
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Dialysis modality-related disparities in sudden cardiac death: hemodialysis versus peritoneal dialysis

Jung HY, Choi H, Choi JY, Cho JH, Park SH, Kim CD, Ryu DR, Kim YL, the ESRD Registry Committee of the Korean Society of Nephrology

BACKGROUND: Patients require risk stratification and preventive strategies for sudden cardiac death (SCD) based on the dialysis modality because the process of dialysis is a risk factor for SCD. This...
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Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells

Kang SH, Kim SW, Kim KJ, Cho KH, Park JW, Kim CD, Do JY

BACKGROUND: We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs). METHODS: We performed in...
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Using Etomidate and Midazolam for Screening Colonoscopies Results in More Stable Hemodynamic Responses in Patients of All Ages

Lee JM, Min G, Keum B, Lee JM, Kim SH, Choi HS, Kim ES, Seo YS, Jeen YT, Chun HJ, Lee HS, Um SH, Kim CD

BACKGROUND/AIMS: Recent studies have demonstrated that etomidate is a safe sedative drug with noninferior sedative effects. In our recent study, we revealed that etomidate/midazolam was more hemodynamically stable than propofol/midazolam...
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Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy

Song EJ, Jeong KH, Yang YA, Lim JH, Jung HY, Choi JY, Cho JH, Kim CD, Kim YL, Park SH

BACKGROUND: Phospholipase A2 receptor (PLA2R) has been identified as a major autoantigen in primary membranous nephropathy (MN). We evaluated the association between anti-PLA2R antibodies and clinical outcome in Korean patients...
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Bortezomib Treatment for Refractory Antibody-Mediated Rejection Superimposed with BK Virus-Associated Nephropathy during the Progression of Recurrent C3 Glomerulonephritis

Do W, Lee JH, Kim KJ, Han MH, Jung HY, Choi JY, Park SH, Kim YL, Kim CD, Cho JH, Yang Y, Kim M, Hwang I, Kim KY, Yim T, Kim YJ

A 38-year-old man, who underwent a second kidney transplantation (KT), was admitted because of antibody-mediated rejection (AMR) complicated by BK virus-associated nephropathy (BKVAN). He was placed on hemodialysis at the...
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