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Radiotherapy for initial clinically positive internal mammary nodes in breast cancer

Kim J, Chang JS, Choi SH, Kim YB, Keum KC, Suh CO, Yang G, Cho Y, Kim JW, Lee IJ

PURPOSE: Internal mammary lymph node (IMN) involvement is associated with poor prognosis in breast cancer. This study investigated the treatment outcomes of initial clinically IMN-positive breast cancer patients who received...
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The Effect of Hospital Case Volume on Clinical Outcomes in Patients with Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Analysis (KROG-1106)

Ha B, Cho KH, Moon SH, Lee CG, Keum KC, Kim YS, Wu HG, Kim JH, Ahn YC, Oh D, Noh JM, Lee JH, Kim SH, Kim WT, Oh YT, Kang MK, Kim JH, Kim JY, Cho MJ, Kay CS, Choi JH

PURPOSE: The purpose of this study was to investigate the effect of hospital case volume on clinical outcomes in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: Data on 1,073 patients...
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External validation of IBTR! 2.0 nomogram for prediction of ipsilateral breast tumor recurrence

Lee BM, Chang JS, Cho YU, Park S, Park HS, Kim JY, Sohn JH, Kim GM, Koo JS, Keum KC, Suh CO, Kim YB

PURPOSE: IBTR! 2.0 nomogram is web-based nomogram that predicts ipsilateral breast tumor recurrence (IBTR). We aimed to validate the IBTR! 2.0 using an external data set. MATERIALS AND METHODS: The cohort...
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Elective neck treatment in clinically node-negative paranasal sinus carcinomas: impact on treatment outcome

Lee WH, Choi SH, Kim SH, Choi EC, Lee CG, Keum KC

PURPOSE: The indication of elective neck treatment (ENT) for clinically N0 (cN0) paranasal sinus (PNS) carcinoma remains unclear. We aimed to investigate different treatment outcomes regarding ENT and propose optimal...
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Prognoses and Clinical Outcomes of Primary and Recurrent Uveal Melanoma

Kim JH, Shin SJ, Heo SJ, Choe EA, Kim CG, Jung M, Keum KC, Yoon JS, Lee SC, Shin SJ

PURPOSE: Uveal melanoma has a very poor prognosis despite successful local primary tumor treatment. In this study, we investigated prognostic factors that more accurately reflected the likelihood of recurrence and...
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Survival and Functional Outcome after Treatment for Primary Base of Tongue Cancer: A Comparison of Definitive Chemoradiotherapy versus Surgery Followed by Adjuvant Radiotherapy

Park S, Cho Y, Lee J, Koh YW, Kim SH, Choi EC, Kim HR, Keum KC, Park KR, Lee CG

PURPOSE: The purpose of this study was to compare the clinical and functional outcomes in patients with primary base of tongue (BOT) cancer who received definitive radiotherapy (RT) or surgery followed...
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Radiotherapy Versus Cordectomy in the Management of Early Glottic Cancer

Chung SY, Kim KH, Keum KC, Koh YW, Kim SH, Choi EC, Lee CG

PURPOSE: The purpose of this study was to compare the treatment outcomes of definitive radiotherapy (RT) with cordectomy in patients with early glottic cancer. MATERIALS AND METHODS: A total of 165...
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Ruthenium-106 Brachytherapy with or without Additional Local Therapy Shows Favorable Outcome for Variable-Sized Choroidal Melanomas in Korean Patients

Cho Y, Chang JS, Yoon JS, Lee SC, Kim YB, Kim JH, Keum KC

PURPOSE: The purpose of this study was to report clinical outcomes of ruthenium-106 (106Ru) brachytherapy with or without additional local therapy for choroidal melanomas in Korean patients. MATERIALS AND METHODS: A...
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Patterns of Care for Radiotherapy in the Neoadjuvant and Adjuvant Treatment of Gastric Cancer: A Twelve-Year Nationwide Cohort Study in Korea

Chang JS, Choi Y, Shin J, Kim KH, Keum KC, Kim HS, Koom WS, Park EC

PURPOSE: Although Korea has the highest incidence of gastric cancer worldwide and D2-lymphadenectomies are routinely performed, radiotherapy (RT) practice patterns have not been well studied. Therefore, we examined RT usage...
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Comparison of the Clinical Outcomes of Patients with Squamous Cell Carcinoma of the Tonsil Receiving Postoperative Ipsilateral Versus Bilateral Neck Radiotherapy: A Propensity Score Matching Analysis (KROG 11-07)

Kim Y, Cho KH, Moon SH, Lee CG, Keum KC, Lee SW, Ahn YC, Oh D, Kim YS, Won YK, Wu HG, Hah JH, Oh YT

PURPOSE: The impact of postoperative ipsilateral neck radiotherapy (INRT) versus bilateral neck radiotherapy (BNRT) on the clinical outcomes of patients with tonsillar squamous cell carcinoma was analyzed retrospectively. MATERIALS AND METHODS:...
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Tumor Stage-Related Role of Radiotherapy in Patients with an External Auditory Canal and Middle Ear Carcinoma

Choi J, Kim SH, Koh YW, Choi EC, Lee CG, Keum KC

PURPOSE: The purpose of this study was to evaluate the clinical outcomes of patients treated with radiotherapy (RT) for a carcinoma of the external auditory canal (EAC) and middle ear. MATERIALS...
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Neoadjuvant chemotherapy followed by surgery has no therapeutic advantages over concurrent chemoradiotherapy in International Federation of Gynecology and Obstetrics stage IB-IIB cervical cancer

Lee J, Kim TH, Kim GE, Keum KC, Kim YB

OBJECTIVE: We aimed to assess the efficacy of neoadjuvant chemotherapy followed by surgery (NACT+S), and compared the clinical outcome with that of concurrent chemoradiotherapy (CCRT) in patients with International Federation...
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Gold nanoparticles enhance anti-tumor effect of radiotherapy to hypoxic tumor

Kim MS, Lee EJ, Kim JW, Chung US, Koh WG, Keum KC, Koom WS

PURPOSE: Hypoxia can impair the therapeutic efficacy of radiotherapy (RT). Therefore, a new strategy is necessary for enhancing the response to RT. In this study, we investigated whether the combination...
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The Clinical Usefulness of ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography (PET) to Predict Oncologic Outcomes and PET-Based Radiotherapeutic Considerations in Locally Advanced Nasopharyngeal Carcinoma

Yoon HI, Kim KH, Lee J, Roh YH, Yun M, Cho BC, Lee CG, Keum KC

PURPOSE: We investigated ¹⁸F-fluorodeoxyglucose positron emission tomography (PET)-derived parameters as prognostic indices for disease progression and survival in locally advanced nasopharyngeal carcinoma (NPC) and the effect of high-dose radiotherapy for...
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The Role of Neoadjuvant Chemotherapy in the Treatment of Nasopharyngeal Carcinoma: A Multi-institutional Retrospective Study (KROG 11-06) Using Propensity Score Matching Analysis

Song JH, Wu HG, Keam BS, Hah JH, Ahn YC, Oh D, Noh JM, Park HJ, Lee CG, Keum KC, Cha J, Cho KH, Moon SH, Kim JY, Chung WK, Oh YT, Kim WT, Cho MJ, Kay CS, Kim YS

PURPOSE: We compared the treatment results and toxicity in nasopharyngeal carcinoma (NPC) patients treated with concurrent chemotherapy (CCRT) alone (the CRT arm) or neoadjuvant chemotherapy followed by CCRT (the NCT...
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18F-FDG/PET May Help to Identify a Subgroup of Patients with T1-T2 Breast Cancer and 1-3 Positive Lymph Nodes Who Are at a High Risk of Recurrence after Mastectomy

Chang JS, Lee J, Kim HJ, Kim KH, Yun M, Kim SI, Keum KC, Suh CO, Kim YB

PURPOSE: The purpose of this study is to assess the utility of positron emission tomography (PET) for predicting recurrence among patients with T1-T2/N1 breast cancer who were treated with mastectomy. MATERIALS...
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Overexpression of SOX2 Is Associated with Better Overall Survival in Squamous Cell Lung Cancer Patients Treated with Adjuvant Radiotherapy

Yoon HI, Park KH, Lee EJ, Keum KC, Lee CG, Kim CH, Kim YB

PURPOSE: The purpose of this study is to investigate the prognostic significance of SOX2 gene amplification and expression in patients with American Joint Committee on Cancer stage III lung squamous...
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Evaluation of Radiation Dose for Dual Energy CBCT Using Multi-Grid Device

Ju EB, Ahn SH, Cho SJ, Keum KC, Lee R

The paper discusses radiation dose of dual energy CT on which copper modulation layer, is mounted in order to improve diagnostic performance of the dual energy CT. The radiation dose...
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Analysis of Beam Hardening of Modulation Layers for Dual Energy Cone-beam CT

Ahn S, Cho SJ, Keum KC, Choi SG, Lee R

Dual energy cone-beam CT can distinguish two materials with different atomic compositions. The principle of dual energy cone-beam CT based on modulation layer is that higher energy spectrum can be...
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An Empirical Approach to Dosimetric Effect of Carbon Fiber Couch for Flattening Filter Free Beam of Elekta LINAC

Ahn S, Park K, Kim J, Lee H, Yoon J, Lee E, Park S, Park J, Kim J, Keum KC

Generally, it is recommended that the dosimetric effect of carbon fiber couch should be considered especially for an intensity-modulated therapy with a large portion of monitor units from posterior angles....
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