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Comparison of age‐dependent alterations in thioredoxin 2 and thioredoxin reductase 2 expressions in hippocampi between mice and rats

Yoo YH, Kim DW, Chen BH, Sim H, Kim B, Lee JC, Ahn JH, Park Y, Cho JH, Kang IJ, Won MH, Lee TK

Background Aging is one of major causes triggering neurophysiological changes in many brain substructures, including the hippocampus, which has a major role in learning and memory. Thioredoxin (Trx) is a class...
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Multicenter Adherence Study of Asthma Medication for Children in Korea

Kim CK, Callaway Z, Choi J, Kim HB, Kwon EM, Chang YS, Rha YH, Hong SJ, Oh JW, Kim HH, Lim DH, Kim SW, Park KS, Cho YH, Chung HL, Park HJ, Jung SG, Kang IJ, Hyun MC, Oh MY, Jung JA, Kim MS, Shim JY, Kim JT, Koh YY, KAPARD Work Group on Asthma Medication Compliance

PURPOSE: Adherence is a major component of successful medical treatment. However, non-adherence remains a barrier to effective delivery of healthcare worldwide. METHODS: Twenty healthcare facilities (secondary or tertiary hospitals) belonging to...
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Timing of Fusarium Head Blight Infection in Rice by Heading Stage

Kim Y, Kang IJ, Shin DB, Roh JH, Heu S, Shim HK

Fusarium graminearum causes the devastating plant disease Fusarium head blight and produces mycotoxins on small cultivated grains. To investigate the timeframe of F. graminearum infection during rice cultivation, a spore...
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Age-dependent differences in myelin basic protein expression in the hippocampus of young, adult and aged gerbils

Ahn JH, Lee TK, Park JH, Cho JH, Kim IH, Lee JC, Hong S, Jeon YH, Kang IJ, Lee YJ, Won MH, Lee CH

Myelin degeneration is one of the characteristics of aging and degenerative diseases. This study investigated age-related alterations in expression of myelin basic protein (MBP) in the hippocampal subregions (dentate gyrus,...
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Synergetic Hepatoprotective Effects of Korean Red Ginseng and Pueraria Radix on the Liver Damaged-Induced by Carbon Tetrachloride (CClâ‚„) in Mice

Hwang SH, Wang Z, Kang IJ, Lim SS

This study was designed to investigate the synergetic hepatoprotective effects from a mixture of Korean Red Ginseng and Pueraria Radix on carbon tetrachloride (CClâ‚„)-induced hepatotoxicity in mice. Liver toxicity was...
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Protective effects of an ethanol extract of Angelica keiskei against acetaminophen-induced hepatotoxicity in HepG2 and HepaRG cells

Choi YH, Lee HS, Chung CK, Kim EJ, Kang IJ

BACKGROUND/OBJECTIVE: Although Angelica keiskei (AK) has widely been utilized for the purpose of general health improvement among Asian, its functionality and mechanism of action. The aim of this study was...
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Pre-treated Populus tomentiglandulosa extract inhibits neuronal loss and alleviates gliosis in the gerbil hippocampal CA1 area induced by transient global cerebral ischemia

Park JH, Lee TK, Ahn JH, Shin BN, Cho JH, Kim IH, Lee JC, Kim JD, Lee YJ, Kang IJ, Hong S, Kim YH, Jeon YH, Lee YL, Won MH

The genus Populus (poplar) belonging to the Salicaceae family has been used in traditional medicine, and its several species show various pharmacological properties including antioxidant and anti-inflammatory effects. No study...
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Increased humoral antibody response of foot-and-mouth disease virus vaccine in growing pigs pre-treated with poly-γ-glutamic acid

Lee JH, Kang IJ, Kim AR, Noh YS, Chung HC, Park BK

This study was conducted to determine if humoral antibody response of foot-and-mouth disease (FMD) vaccine improved in 8-week-old growing pigs born to well-vaccinated sows pre-treated with 60 mg of poly-γ-glutamic...
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Changes in Sensitization Rate to Weed Allergens in Children with Increased Weeds Pollen Counts in Seoul Metropolitan Area

Kim JH, Oh JW, Lee HB, Kim SW, Kang IJ, Kook MH, Kim BS, Park KS, Baek HS, Kim KR, Choi YJ

The prevalence of allergic diseases in children has increased for several decades. We evaluated the correlation between pollen count of weeds and their sensitization rate in Seoul, 1997-2009. Airborne particles...
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Multicenter Study on Factors Influencing the Quality of Life of Asthmatic Children and Their Caregivers

Cho AR, Lee SY, Kim YH, Yoo Y, Yang HJ, Lee JS, Song TW, Kim WK, Hong SJ, Kang IJ, Lee HR

  • KMID: 2315209
  • Pediatr Allergy Respir Dis.
  • 2012 Mar;22(1):37-44.
PURPOSE: Pediatric asthma is the most common chronic disease in children. It negatively affects the health-related quality of life (QoL) in children with this disease and of their caregivers. This...
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The Revised Edition of Korean Calendar for Allergenic Pollens

Oh JW, Lee HB, Kang IJ, Kim SW, Park KS, Kook MH, Kim BS, Baek HS, Kim JH, Kim JK, Lee DJ, Kim KR, Choi YJ

The old calendar of pollens did not reflect current pollen distribution and concentrations that can be influenced by changes of weather and environment of each region in South Korea. A...
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Association of Respiratory Viral Infection and Atopy with Severity of Acute Bronchiolitis in Infants

Kim HJ, Kim JH, Kang IJ

  • KMID: 2315156
  • Pediatr Allergy Respir Dis.
  • 2011 Dec;21(4):302-312.
PURPOSE: We investigated the influence of respiratory virus and atopic characteristics on the severity of bronchiolitis. METHODS: Four hundred and eighteen infants
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The Influence of Atopic Findings on Severity of Pneumonia in Children with 2009 Pandemic Influenza A (H1N1) Infection

Kim JH, Kim HJ, Kang IJ

  • KMID: 2278979
  • Korean J Pediatr Infect Dis.
  • 2011 Dec;18(2):182-192.
PURPOSE: Atopic findings may be associated with severity of pneumonia in 2009 pandemic influenza A (H1N1) infection, which could suggest a possible association between atopic findings and the severity of...
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The Influence of Respiratory Virus and Atopy on Recurrence of Virus Induced Wheezing in Children

Ahn BW, Lee DH, Kang IJ

  • KMID: 2315025
  • Pediatr Allergy Respir Dis.
  • 2010 Sep;20(3):179-187.
PURPOSE: We studied to know the influence of respiratory virus and atopic characteristics on recurrence of virus-induced wheezing in children under 3 years of age. METHODS: Between March 2006 and February...
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A Case of Non-occulsive Mesentery Ischemia with Pulmonary Embolism due to Protein C Deficiency

Kim TW, Choi SY, Kang IJ, Kang YJ, Shin DH

Protein C is an important physiological anticoagulant factor. Protein C deficiency has been linked to venous thrombosis at unusual sites, including the cerebral and mesenteric veins. Hereditary protein C deficiency...
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Risk Factors for Adenoid Hypertrophy in Children with Allergic Rhinitis

  • KMID: 2299526
  • Korean J Asthma Allergy Clin Immunol.
  • 2010 Dec;30(4):299-306.
BACKGROUND: Many children who have allergic rhinitis (AR) have adenoid hypertrophy (AH) which can cause significant morbidity. OBJECTIVE: To know the risk factors for AH in children with AR. METHOD: 208 children...
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Association between nasogastric tube insertion and aspiration pneumonia in drug intoxication

Ghim BK, Choi SY, Kang IJ, Kang YJ, Kwon BS, Lee JE, Seo MH, Lee TH, Park SK

  • KMID: 2259207
  • Korean J Med.
  • 2010 Jan;78(1):87-94.
BACKGROUND/AIMS: The clinical usefulness of nasogastric tube insertion in poisoning patients is controversial. This study compared the incidence of aspiration pneumonia between patients with or without nasogastric tubes. METHODS: We retrospectively...
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Factors Associated with the Development of Wheezing in Late Childhood with Cough-Variant Asthma

  • KMID: 2299561
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Sep;29(3):171-178.
BACKGROUND: Cough-variant asthma (CVA) is a phenotype of asthma solely presenting with persistent cough. It shares several features of classic asthma (CA) with wheezing including atopy, bronchial hyperresponsiveness (BHR) and...
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Relationship between Total Serum IgE Level and Allergic Sensitization/Bronchial Hyperresponsiveness in Preschool Children with Asthma

Jun JS, Yun KT, Kang IJ

  • KMID: 1474537
  • Pediatr Allergy Respir Dis.
  • 2009 Sep;19(3):260-270.
PURPOSE: This study aimed to evaluate the relationship between the serum IgE level and allergic sensitization/bronchial hyperresponsiveness (BHR) in preschool children with asthma. METHODS: One hundred nine asthmatic children age 4-6...
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Dengue Fever Mimicking Acute Appendicitis: A Case Report

Kang YJ, Choi SY, Kang IJ, Lee JE, Seo MH, Lee TH, Ghim BK

We experienced a case of enteritis mimicking acute appendicitis in Dengue fever. This is the first case report of such complication in Korea. A 36-year-old man presented with fever and...
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