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Urinary microRNA-1913 to microRNA-3659 expression ratio as a non-invasive diagnostic biomarker for prostate cancer

Byun YJ, Piao XM, Jeong P, Kang HW, Seo SP, Moon SK, Lee JY, Choi YH, Lee HY, Kim WT, Lee SC, Cha EJ, Yun SJ, Kim WJ

Purpose: MicroRNAs (miRNAs) are small non-coding RNAs and are involved in the development, proliferation, and pathogenesis of prostate cancer (PCa). Urinary miRNAs are promising non-invasive biomarkers for PCa diagnosis because...
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A high basal metabolic rate is an independent predictor of stone recurrence in obese patients

Kang HW, Seo SP, Lee HY, Kim K, Ha YS, Kim WT, Kim YJ, Yun SJ, Kim WJ, Lee SC

Purpose: Basal metabolic rate (BMR) is an indicator of overall body metabolism and may portend unique aberrations in urine physico-chemistry and stone recurrence. The present study examined the effect of...
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Effect of fluoride release on the polished surface after polishing with a bur containing fluoride

Jeong IS, Kang HW, Yun KD

This study aimed to evaluate the fluoride release amount on the polished surface after polishing with a bur containing fluoride. The point-shape dental burs and disk-shape specimens containing 1,450 ppm fluoride...
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Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: Incorporating Considerations of Resources Use into Grading Recommendations’ (A Secondary Publication)

Kim HW, Jung JH, Kim DK, Kang HW, Ku JY, Jung HJ, Hwang EC, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

This article is the fifth translation of a GRADE series published in the BMJ for incorporating the considerations of resources use into grading recommendations. Clinical recommendations inevitably involve judgments about the...
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A novel urinary mRNA signature using the droplet digital polymerase chain reaction platform improves discrimination between prostate cancer and benign prostatic hyperplasia within the prostate-specific antigen gray zone

Kang HW, Lee HY, Byun YJ, Jeong P, Yoon JS, Kim DH, Kim WT, Kim YJ, Lee SC, Yun SJ, Kim WJ

Purpose: The aim of this study was to identify a noninvasive urinary marker for prostate cancer (PCa) diagnosis and to validate the clinical performance of this novel urinary mRNA signature...
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Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: Grading Quality of Evidence and Strength of Recommendations for Diagnostic Tests and Strategies’ (A Secondary Publication)

Jung JH, Kim DK, Kang HW, Ku JY, Jung HJ, Kim HW, Hwang EC, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

This article is the fourth translation of a GRADE series published in the BMJ, which graded the quality of evidence and strength of recommendations for diagnostic tests or strategies, as...
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Primary Angiosarcoma of the Mesentery: A Case Report

Kang HW, Shin JY, Choi JW

Angiosarcoma is a malignant endothelial cell tumor of lymphatic or vascular origin and is most commonly found in the skin and soft tissue. Primary mesenteric angiosarcoma has rarely been reported....
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Effect of Leg Elevation Height on Reduced Swelling of Patients of Postoperative Acute Ankle Fractures

Seo DK, Kang HW, Ahn DS, Song JS

Purpose: Leg elevation is known as an effective method for reducing leg swelling, and it has been routinely used in medical practice. However, the effect of swelling reduction in relation...
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Korean Translation of the GRADE Series Published in the BMJ, ‘Use of GRADE Grid to Reach Decisions on Clinical Practice Guidelines When Consensus Is Elusive’ (A Secondary Publication)

Jung HJ, Hwang EC, Kim DK, Kang HW, Ku JY, Kim HW, Jung JH, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

This article is the last of a series providing guidance for the use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system for rating the quality of evidence...
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Results of total knee arthroplasty for painless, stiff knees

Choi YJ, Seo DK, Lee KW, Ra HJ, Kang HW, Kim JK

Background Stiff knees, like completely ankylosed or arthrodesed knees, can be painless. Total knee arthroplasty (TKA) for these painless, stiff knees is technically demanding. However, it can correct the alignment and...
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Identification of urinary microRNA biomarkers for in vivo gentamicininduced nephrotoxicity models

Jeon BS, Lee Sh, Hwang SR, Yi H, Bang JH, Tham NTT, Lee HK, Woo GH, Kang HG, Ku HO

Background: Although previous in vivo studies explored urinary microRNA (miRNA), there is no agreement on nephrotoxicity-specific miRNA biomarkers. Objectives: In this study, we assessed whether urinary miRNAs could be employed as...
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Vegetarianism as a protective factor for asymptomatic colonic diverticulosis in Asians: a retrospective cross-sectional and case-control study

Bong J, Kang HW, Cho H, Nam JH, Jang DK, Kim JH, Lee JK, Lim YJ, Koh MS, Lee JH

Background/Aims: Dietary fiber intake is considered a protective factor for diverticular disease such as diverticulitis. However, evidence for an inverse connection between dietary fiber consumption and asymptomatic colonic diverticulosis is...
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Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: What Is “Quality of Evidence” and Why Is It Important to Clinicians?’ (A Secondary Publication)

Kang HW, Jung JH, Kim DK, Ku JY, Jung HJ, Kim HW, Hwang EC, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

This article is second translation of a GRADE series published in the BMJ to create a highly structured, transparent, and informative system for rating quality of evidence for developing recommendations....
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Early-onset Colorectal Cancer

Jeong MA, Kang HW

The incidence of colorectal cancer (CRC) is increasing among young adults in several countries including the United States. Early-onset colorectal cancer (EO-CRC) is heterogenous group and appears to have a...
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Methylation Signature for Prediction of Progression Free Survival in Surgically Treated Clear Cell Renal Cell Carcinoma

Kang HW, Park H, Seo SP, Byun YJ, Piao XM, Kim SM, Kim WT, Yun SJ, Jang W, Shon HS, Ryu KH, Lee SC, Kim WJ, Kim YJ

BACKGROUND: Little is known about epigenetic silencing of genes by promoter hypermethylation in renal cell carcinoma (RCC). The aim of this study was to identify prognostic methylation markers in surgically...
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Trends in clinical, operative, and pathologic characteristics of surgically treated renal mass in a Korean center: A surgical series from 1988 through 2015

Kang HW, Seo SP, Kim WT, Yun SJ, Lee SC, Kim WJ, Hwang EC, Kang SH, Hong SH, Chung J, Kwon TG, Kim HH, Kwak C, Byun SS, Kim YJ, KORCC (KOrean Renal Cell Carcinoma) Group

PURPOSE: To analyze trends over a period of 28 years in the clinical, operative, and pathologic characteristics of patients with a renal mass who underwent surgical resection in Korea. MATERIALS AND...
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Metabolic Syndrome Is an Independent Risk Factor for Acquired Premature Ejaculation

Jeh SU, Yoon S, Choi JH, Do J, Seo DH, Lee SW, Choi SM, Lee C, Kam SC, Hwa JS, Chung KH, Kang HW, Hyun JS

PURPOSE: To determine the role of metabolic syndrome (MetS) as a risk factor for acquired premature ejaculation (PE) after considering the various risk factors, such as lower urinary tract symptoms,...
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Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: An Emerging Consensus on Rating Quality of Evidence and Strength of Recommendations’ (A Secondary Publication)

Kim DK, Hwang EC, Kang HW, Ku JY, Jung HJ, Kim HW, Jung JH, Guideline Development Committee in the Korean Association of Urogenital Tract Infection and Inflammation

Clinical practice guidelines are statements that include recommendations intended to optimize patient care based on a systematic review of the evidence assessing the benefits and harm of alternative care options....
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Guideline on safety evaluation of cell-based medicinal products for animal use

Ku HO, Yi H, Park YI, Jeon BS, Kang HG, Kim YS, Park BK

With the increased use of cell therapy in the veterinary sector, there is a growing demand for the development of cell-based medicinal products and the determination of their safety. Currently,...
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Acetylcholinesterase activity in the brain of wild birds in Korea—2014 to 2016

Bang JH, Ku HO, Kang HG, Kim H, Kim S, Park SW, Kim YS, Jang I, Bae YC, Woo GH, Yi H

Acetylcholinesterase (AChE) activity level can be used as a diagnostic marker for anticholinesterase pesticide poisoning. In this study, we aimed to establish a baseline level of normal brain AChE activity...
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