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Immune landscape and biomarkers for immuno-oncology in colorectal cancers

Bae JM, Yoo SY, Kim JH, Kang GH

Recent advances in immuno-oncology have increased understanding of the tumor immune microenvironment (TIME), and clinical trials for immune checkpoint inhibitor treatment have shown remission and/or durable response in certain proportions...
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Association between body temperature measured at the emergency department with prognosis in septic shock patients

Choi JH, Park YS, Chung SP, Shin TG, Kim WY, Choi SH, Jo YH, Kang GH, Shin J, Lim TH, Han KS, Suh GJ, Korean Shock Society (KoSS) Investigators

  • KMID: 2506061
  • J Korean Soc Emerg Med.
  • 2020 Aug;31(4):346-354.
Objective: Prior studies have explored the relationship between initial body temperature (BT) and mortality in patients with sepsis in the emergency department (ED). However, there has been no study on...
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Evolving pathologic concepts of serrated lesions of the colorectum

Kim JH, Kang GH

Here, we provide an up-to-date review of the histopathology and molecular pathology of serrated colorectal lesions. First, we introduce the updated contents of the 2019 World Health Organization classification for...
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Prognostic factors related with outcomes in traumatic out-of-hospital cardiac arrest patients without prehospital return of spontaneous circulation:a nationwide observational study

Jun GS, Kim JG, Choi HY, Kang GH, Kim W, Jang YS, Kim HT

Objective To evaluate the prognostic factors associated with the sustained return of spontaneous circulation (ROSC) and survival to hospital discharge in traumatic out-of-hospital cardiac arrest (TOHCA) patients without prehospital ROSC. Methods...
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Successful Treatment of a Korean Infant with Giant Cell Hepatitis with Autoimmune Hemolytic Anemia Using Rituximab

Kim YH, Kim JW, Lee EJ, Kang GH, Kang HJ, Moon JS, Ko JS

Giant cell hepatitis with autoimmune hemolytic anemia (AHA) is a rare disease of infancy characterized by the presence of both Coombs-positive hemolytic anemia and progressive liver disease with giant cell...
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Standardized Pathology Report for Colorectal Cancer, 2nd Edition

Kim Bh, Kim JM, Kang GH, Chang HJ, Kang DW, Kim JH, Bae JM, Seo AN, Park HS, Kang YK, Lee KH, Cho MY, Do IG, Lee HS, Chang HK, Park DY, Kang HJ, Sohn JH, Chang MS, Jung ES, Jin SY, Yu E, Han HS, Kim YW, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of the ‘Standardized Pathology Report for Colorectal Cancer,’ which was developed by the Gastrointestinal Pathology Study Group (GIP) of the Korean Society of Pathologists, was published 13...
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Fibroblast Growth Factor Receptor 1 (FGFR1) Amplification Detected by Droplet Digital Polymerase Chain Reaction (ddPCR) Is a Prognostic Factor in Colorectal Cancers

Bae JM, Wen X, Kim TS, Kwak Y, Cho NY, Lee HS, Kang GH

Purpose The purpose of this study was to reveal the clinicopathological characteristics and prognostic implications associated with fibroblast growth factor receptor 1 (FGFR1) amplification in colorectal cancers (CRCs). Materials and Methods We measured...
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Clinicopathological Characterization and Prognostic Implication of SMAD4 Expression in Colorectal Carcinoma

Yoo SY, Lee JA, Shin Y, Cho NY, Bae JM, Kang GH

BACKGROUND: SMAD family member 4 (SMAD4) has gained attention as a promising prognostic factor of colorectal cancer (CRC) as well as a key molecule to understand the tumorigenesis and progression...
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CpG Island Methylation in Sessile Serrated Adenoma/Polyp of the Colorectum: Implications for Differential Diagnosis of Molecularly High-Risk Lesions among Non-dysplastic Sessile Serrated Adenomas/Polyps

Lee JA, Park HE, Yoo SY, Jeong S, Cho NY, Kang GH, Kim JH

BACKGROUND: Although colorectal sessile serrated adenomas/polyps (SSA/Ps) with morphologic dysplasia are regarded as definite high-risk premalignant lesions, no reliable grading or risk-stratifying system exists for non-dysplastic SSA/Ps. The accumulation of...
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Impact of Mucin Proportion in the Pretreatment MRI on the Outcomes of Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiotherapy

Kim E, Kim K, Kim SH, Han SW, Kim TY, Jeong SY, Park KJ, Koh J, Kang GH, Chie EK

PURPOSE: The purpose of this study was to evaluate treatment response to neoadjuvant chemoradiotherapy (CRT) with regard to mucin status in pathology and pretreatment magnetic resonance imaging (MRI) in locally...
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Three-axis Modification of Coordinates Enables Accurate Stereotactic Targeting in Non-human Primate Brains of Different Sizes

Kim HS, Kang GH, Song H, Kim RG, Park JY, Hwang JH, Kim HI

The brain grows with age in non-human primates (NHPs). Therefore, atlas-based stereotactic coordinates cannot be used directly to target subcortical structures if the size of the animal's brain differs from...
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Benign Recurrent Intrahepatic Cholestasis Type 2 in Siblings with Novel ABCB11 Mutations

Sohn MJ, Woo MH, Seong MW, Park SS, Kang GH, Moon JS, Ko JS

Benign recurrent intrahepatic cholestasis (BRIC), a rare cause of cholestasis, is characterized by recurrent episodes of cholestasis without permanent liver damage. BRIC type 2 (BRIC2) is an autosomal recessive disorder...
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Chronic Medical Diseases and Depressive Symptoms in a Rural Group at High Risk for Depression: A 1-Year Follow-Up Study

Chung BS, Lee D, Choi JW, Oh HO, Kang GH, Lee SS, Kim BJ, Lee CS, Lee SJ, Seo JY, Lee YJ, Cha B, Park CS

OBJECTIVES: This study investigated the effects of chronic medical diseases on depressive symptoms in individuals at high risk for depression living in rural areas, over a 1-year period. METHODS: A community-based...
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Prognostic Impact of Fusobacterium nucleatum Depends on Combined Tumor Location and Microsatellite Instability Status in Stage II/III Colorectal Cancers Treated with Adjuvant Chemotherapy

Oh HJ, Kim JH, Bae JM, Kim HJ, Cho NY, Kang GH

BACKGROUND: This study aimed to investigate the prognostic impact of intratumoral Fusobacterium nucleatum in colorectal cancer (CRC) treated with adjuvant chemotherapy. METHODS: F. nucleatum DNA was quantitatively measured in a total...
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Prognostic Significance of EPHB2 Expression in Colorectal Cancer Progression

Jang BG, Kim HS, Chang WY, Bae JM, Kang GH

BACKGROUND: A receptor tyrosine kinase for ephrin ligands, EPHB2, is expressed in normal colorectal tissues and colorectal cancers (CRCs). The aim of this study was to investigate EPHB2 expression over...
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A Real Situation Experimental Study on The Thermal Protection Performance of Firefighter Clothes and Gloves

Lee WJ, Kang GH, Jang YS, Kim W, Choi HY, Kim JG, Kim M, Seo K, kim DH, Lee JY, Choi JY

PURPOSE: This study aimed to evaluate the thermal protective function of firefighter clothes and gloves through real scale fire simulations. METHODS: Firstly, the fire simulation by real scale flame was performed...
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Pre-hospital i-gel blind intubation for trauma: a simulation study

Kim JG, Kim W, Kang GH, Jang YS, Choi HY, Kim H, Kim M

OBJECTIVE: This study aimed to evaluate the efficacy of i-gel blind intubation (IGI) as a rescue device for definitive airway management in ground intubation for pre-hospital trauma patients. METHODS: A prospective...
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2014–2017 Nationwide Bariatric and Metabolic Surgery Report in Korea

Kwon IG, Kim JW, Kang GH, Kim DW, Kim SG, Kim SM, Kim SS, Kim YJ, Kim W, Kim JH, Kim JH, Kim JJ, Kim HG, Ryu SW, Park DJ, Park DJ, Park SS, Park YC, Park JM, Park JY, Seo KW, Suh BJ, Ahn SM, Ahn HS, Yoo MW, Lee SK, Lee HH, Lee HJ, Jun KH, Jung KO, Cho M, Choi SH, Ha MH, Ha TK, Han SM, Han SU, Heo YS, Hyung WJ, Lee JH, on behalf of the Information Committee of the Korean Society of Bariatric and Metabolic Surgery

PURPOSE: The information committee of the Korean Society for Metabolic and Bariatric Surgery (KSMBS) performed the nationwide survey of bariatric and metabolic operations to report IFSO (International Federation for the...
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Multiplicity of Advanced T Category–Tumors Is a Risk Factor for Survival in Patients with Colorectal Carcinoma

Park HE, Yoo S, Bae JM, Jeong S, Cho NY, Kang GH

BACKGROUND: Previous studies on synchronous colorectal carcinoma (SCRC) have reported inconsistent results about its clinicopathologic and molecular features and prognostic significance. METHODS: Forty-six patients with multiple advanced tumors (T2 or higher...
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Analysis of the association of serum potassium and lactic acid with neurologic outcome in out-of hospital post-cardiac arrest adult patients

Lee YH, Kim W, Kang GH, Jang YS, Choi HY, Kim JG

OBJECTIVE: This study aimed to identify the effects of serum potassium and lactate on neurologic outcomes in out-of-hospital post-cardiac arrest adult patients. METHODS: This study was a single center, retrospective observational...
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