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Severe Thrombocytopenia in a Patient with COVID-19

Nham E, Ko JH, Jeong BH, Huh K, Cho SY, Kang CI, Chung DR, Peck KR

Coronavirus disease 2019 (COVID-19) outbreak is spreading rapidly all over the world, being a major threat to public health. Since clinical feature of COVID-19 has not been fully evaluated yet,...
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Analysis of the Change in Seropositive Rate of the Epstein-Barr Virus in Koreans: A Single-Center Study

Kim SK, Choi JS, Kim D, Kang CI, Chung DR, Peck KR, Kang ES, Kim YJ

Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate...
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Characteristics and Clinical Outcomes of Extended-Spectrum beta-lactamaseproducing Klebsiella pneumoniae Bacteremia in Cancer Patients

Nham E, Huh K, Cho SY, Chung DR, Peck KR, Lee NY, Kang CI

Background: Cancer patients can be at a higher risk of infection due to drug-resistant bacteria than the general population for various reasons. We performed a retrospective study to evaluate possible...
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Therapeutic Drug Level Monitoring of Teicoplanin in Korean Pediatric Patients with Normal versus Impaired Renal Function

Choi Js, Kim JM, Kim D, Kim SH, Cho H, Park HD, Lee SY, Kang CI, Kim YJ

Background: Teicoplanin is used to treat serious gram-positive infections. Optimal teicoplanin trough levels are considered to be ≥ 10 μg/mL. Despite its wide use in various clinical settings, data on...
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Clinical impact of healthcare-associated acquisition in cirrhotic patients with community-onset spontaneous bacterial peritonitis

Kim J, Kang CI, Gwak GY, Chung DR, Peck KR, Song JH

Background/Aims: Healthcare-associated (HCA) infection is a recently suggested new category of community-onset infections. The implications of HCA infections in terms of diagnosis, treatment, and outcomes of spontaneous bacterial peritonitis (SBP)...
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Comparison of 16S Ribosomal RNA Targeted Sequencing and Culture for Bacterial Identification in Normally Sterile Body Fluid Samples: Report of a 10-Year Clinical Laboratory Review

Yoo IY, Kang OK, Lee MK, Kim YJ, Cho SY, Huh K, Kang CI, Chung DR, Peck KR, Huh HJ, Lee NY

As 16S ribosomal RNA (rRNA)-targeted sequencing can detect DNA from non-viable bacteria, it can be used to identify pathogens from clinical samples even in patients pretreated with antibiotics. We compared...
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Erratum: Antimicrobial Therapy for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria

Wi YM, Kang CI

The original version of the article contained error.
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Reevaluation of the impact of methicillin-resistance on outcomes in patients with Staphylococcus aureus bacteremia and endocarditis

Joo EJ, Park DA, Kang CI, Chung DR, Song JH, Lee SM, Peck KR

BACKGROUND/AIMS: Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in hospitals, and has recently emerged in the community. The impact of methicillin-resistance on mortality and medical costs for patients with S....
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Evaluation of a Carbapenem-Saving Strategy Using Empirical Combination Regimen of Piperacillin-Tazobactam and Amikacin in Hemato-Oncology Patients

Ko JH, Kim SH, Kang CI, Cho SY, Lee NY, Chung DR, Peck KR, Song JH

We implemented a carbapenem-saving strategy in hemato-oncology patients from 2013, using an empirical combination of piperacillin-tazobactam and amikacin for high-risk hemato-oncology patients with febrile neutropenia, who remain hemodynamically unstable >...
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Guideline for Antibiotic Use in Adults with Community-acquired Pneumonia

Lee MS, Oh JY, Kang CI, Kim ES, Park S, Rhee CK, Jung JY, Jo KW, Heo EY, Park DA, Suh GY, Kiem S

Community-acquired pneumonia is common and important infectious disease in adults. This work represents an update to 2009 treatment guideline for community-acquired pneumonia in Korea. The present clinical practice guideline provides...
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Clinical Practice Guidelines for the Antibiotic Treatment of Community-Acquired Urinary Tract Infections

Kang CI, Kim J, Park DW, Kim BN, Ha US, Lee SJ, Yeo JK, Min SK, Lee H, Wie SH

Urinary tract infections (UTIs) are infectious diseases that commonly occur in communities. Although several international guidelines for the management of UTIs have been available, clinical characteristics, etiology and antimicrobial susceptibility...
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Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase

Seok H, Cha MK, Kang CI, Cho SY, Kim SH, Ha YE, Chung DR, Peck KR, Song JH

While carbapenems are the drug of choice to treat extended-spectrum-β-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens are suggested for antibiotic stewardship. We experienced a case of ciprofloxacin treatment failure for...
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Changes in Cytomegalovirus Seroprevalence in Korea for 21 Years: a Single Center Study

Choi SR, Kim KR, Kim DS, Kang JM, Kim SJ, Kim JM, Oh SY, Kang CI, Chung DR, Peck KR, Kang ES, Kim YJ

PURPOSE: Cytomegalovirus (CMV) infection is mostly asymptomatic but can be detrimental to certain hosts. We investigated changes of CMV seroprevalence in Koreans before and after the year 2000. METHODS: We reviewed...
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Antimicrobial Therapy for Infections Caused by Carbapenem-Resistant Gram-Negative Bacteria

Wi YM, Kang CI

Carbapenem-resistance emerging in Gram-negative pathogens, such as Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii, has become a major human health problem globally. The therapeutic options available for carbapenem-resistant pathogens are...
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Risk factors for poor prognosis in nosocomial infective endocarditis

Hwang JW, Park SW, Cho EJ, Lee GY, Kim EK, Chang SA, Park SJ, Lee SC, Kang CI, Chung DR, Peck KR, Song JH

BACKGROUND/AIMS: The aim of our study was to compare the characteristics of nosocomial infective endocarditis (NIE) with community-acquired infective endocarditis (CIE) and to determine independent risk factors for in-hospital death. METHODS:...
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Emergence of Community-Genotype Methicillin-Resistant Staphylococcus aureus in Korean Hospitals: Clinical Characteristics of Nosocomial Infections by Community-Genotype Strain

Joo EJ, Chung DR, Kim SH, Baek JY, Lee NY, Cho SY, Ha YE, Kang CI, Peck KR, Song JH

BACKGROUND: As community-genotype methicillin-resistant Staphylococcus aureus (MRSA) strains spread into hospitals, the genotypes of the MRSA strains causing hospital-acquired (HA) infections have become more diverse. We describe clinical characteristics of...
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First Case of Echinocandin-Resistant Candida albicans in Korea

Park MS, Park JE, Song DJ, Huh HJ, Park S, Kang CI, Shin JH, Lee NY

No abstract available.
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Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak

Park GE, Kang CI, Ko JH, Cho SY, Ha YE, Kim YJ, Peck KR, Song JH, Chung DR

A case-control study was performed to identify clinical predictors for Middle East respiratory syndrome coronavirus (MERS-CoV) infection among patients with acute febrile illness during the nosocomial outbreak. Patients with MERS-CoV...
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Importance of Specimen Type and Quality in Diagnosing Middle East Respiratory Syndrome

Huh HJ, Ko JH, Kim YE, Park CH, Hong G, Choi R, Yu S, Cho SY, Kang JM, Lee MK, Ki CS, Kang ES, Lee NY, Kim JW, Kim YJ, Ha YE, Kang CI, Chung DR, Peck KR, Song JH

No abstract available.
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Risk factors and molecular epidemiology of community-onset, multidrug resistance extended-spectrum β-lactamase-producing Escherichia coli infections

Park SY, Kang CI, Wi YM, Chung DR, Peck KR, Lee NY, Song JH

BACKGROUND/AIMS: Although multidrug resistance (MDR) among extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) poses significant therapeutic challenges, little is known regarding the risk factors and epidemiology of community-onset MDR-ESBL-EC infections. We performed...
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