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ZNF804A Gene Variants Have a Cross-diagnostic Influence on Psychosis and Treatment Improvement in Mood Disorders

Calabrò M, Mandelli L, Crisafulli C, Nicola MD, Colombo R, Janiri L, Lee SJ, Jun TY, Wang SM, Masand PS, Patkar AA, Han C, Pae CU, Serretti A

Objective: Genetic variations in the gene encoding zinc finger protein 804A gene (ZNF804A) have been associated with major depression and bipolar disorder. In this work we focused on the potential...
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Genes Involved in Neurodevelopment, Neuroplasticity and Major Depression: No Association for CACNA1C, CHRNA7 and MAPK1

Calabrò M, Mandelli L, Crisafulli C, Lee SJ, Jun TY, Wang SM, Patkar AA, Masand PS, Han C, Pae CU, Serretti A

OBJECTIVE: Genetics factors are likely to play a role in the risk, clinical presentation and treatment outcome in major depressive disorder (MDD). In this study, we investigated the role of...
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Erratum: Correction of Acknowledgements Second Generation Antipsychotics in the Treatment of Major Depressive Disorder: An Update

Wang SM, Han C, Lee SJ, Jun TY, Patkar AA, Masand PS, Pae CU

The Acknowledgement was published incorrectly.
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Clinical Validation of the Psychotic Depression Assessment Scale, Hamilton Depression Rating Scale-6, and Brief Psychiatric Rating Scale-5: Results from the Clinical Research Center for Depression Study

Park SC, Jang EY, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

OBJECTIVE: The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the...
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Paroxetine versus Venlafaxine and Escitalopram in Korean Patients with Major Depressive Disorder: A Randomized, Rater-blinded, Six-week Study

Woo YS, McIntyre R, Kim JB, Lee MS, Kim JM, Yim HW, Jun TY

OBJECTIVE: The purpose of this study was to compare the efficacy and safety of escitalopram, paroxetine and venlafaxine in Korean patients with major depressive disorder (MDD). METHODS: A total of 449...
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Second Generation Antipsychotics in the Treatment of Major Depressive Disorder: An Update

Wang SM, Han C, Lee SJ, Jun TY, Patkar AA, Masand PS, Pae CU

Less than one third of patients who suffer from major depressive disorder (MDD) report remission following antidepressant treatments requiring more diverse treatment approaches. Augmentation of second generation antipsychotics (SGAs) has...
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Necrotizing soft tissue infection: analysis of the factors related to mortality in 30 cases of a single institution for 5 years

Park SJ, Kim DH, Choi CI, Yun SP, Kim JH, Seo HI, Jo HJ, Jun TY

PURPOSE: Necrotizing soft tissue infection is the infection of the soft tissue with necrotic changes. It is rare, but results in high mortality. We analyzed the characteristics of patients, prognosis,...
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Potential Relationship between Season of Birth and Clinical Characteristics in Major Depressive Disorder in Koreans: Results from the CRESCEND Study

Park SC, Sakong JK, Koo BH, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

We aimed to examine the potential relationship between season of birth (SOB) and clinical characteristics in Korean patients with unipolar non-psychotic major depressive disorder (MDD). Using data from the Clinical...
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Clinical Significance of the Number of Depressive Symptoms in Major Depressive Disorder: Results from the CRESCEND Study

Park SC, Sakong J, Koo BH, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

Our study aimed to establish the relationship between the number of depressive symptoms and the clinical characteristics of major depressive disorder (MDD). This would enable us to predict the clinical...
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Prevalence of Depressive Disorder of Outpatients Visiting Two Primary Care Settings

Jo SJ, Yim HW, Jeong H, Song HR, Ju SY, Kim JL, Jun TY

OBJECTIVES: Although the prevalence of depressive disorders in South Korea's general population is known, no reports on the prevalence of depression among patients who visit primary care facilities have been...
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Optimizing the Use of Aripiprazole Augmentation in the Treatment of Major Depressive Disorder: From Clinical Trials to Clinical Practice

Han C, Wang SM, Lee SJ, Jun TY, Pae CU

Major depressive disorder (MDD) is a recurrent, chronic, and devastating disorder leading to serious impairment in functional capacity as well as increasing public health care costs. In the previous decade,...
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Gender Differences in the Clinical Characteristics of Psychotic Depression: Results from the CRESCEND Study

Park SC, Ostergaard SD, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

OBJECTIVE: To test whether there are gender differences in the clinical characteristics of patients with psychotic depression (PD). METHODS: Using data from the Clinical Research Center for Depression (CRESCEND) study in...
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Difference in Treatment Outcome in Hospitalized Major Depression Patients with versus without Anxious Distress Specifier in DSM-5

Kim SW, Wang HR, Woo YS, Jun TY, Bahk WM

OBJECTIVE: In Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5), a new specifier of major depressive disorder (MDD) "with anxious distress" allows characterization of additional symptoms. The aim...
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Hazardous Drinking-Related Characteristics of Depressive Disorders in Korea: The CRESCEND Study

Park SC, Lee SK, Oh HS, Jun TY, Lee MS, Kim JM, Kim JB, Yim HW, Park YC

This study aimed to identify clinical correlates of hazardous drinking in a large cohort of Korean patients with depression. We recruited a total of 402 depressed patients aged > 18...
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Distinctive Clinical Correlates of Psychotic Major Depression: The CRESCEND Study

Park SC, Lee HY, Sakong JK, Jun TY, Lee MS, Kim JM, Kim JB, Yim HW, Park YC

  • KMID: 2316349
  • Psychiatry Investig.
  • 2014 Jul;11(3):281-289.
OBJECTIVE: The purpose of this investigation was to identify distinctive clinical correlates of psychotic major depression (PMD) as compared with non-psychotic major depression (NPMD) in a large cohort of Korean...
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A Trend of Medication Prescription Pattern for Outpatients with Bipolar Disorder in a University Hospital: Focusing on Atypical Antipsychotics

Lee SM, Shim IH, Woo YS, Jun TY, Bahk WM

  • KMID: 2287775
  • Korean J Psychopharmacol.
  • 2014 Jul;25(3):124-133.
OBJECTIVE: Atypical antipsychotics and newly developed anticonvulsants have become increasingly popular medication for bipolar disorder. Especially, atypical antipsychotics have increasing importance in treatment of bipolar disorder and a number of...
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A Trend of Drug Use in Inpatients with Bipolar Disorder: Comparing 2009-2012 with 1998-2001 in One University Hospital

Cha JM, Shim IH, Woo YS, Jun TY, Bahk WM

  • KMID: 2287774
  • Korean J Psychopharmacol.
  • 2014 Jul;25(3):114-123.
OBJECTIVE: The aim of this study was to monitor changes of prescription trends for bipolar disorder in inpatient settings in one university hospital. METHODS: A retrospective chart review was performed and...
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A Case of Gastric Signet Ring Cell Carcinoma in Young Adult with Nodular Gastritis; On Follow-up without Helicobacter pylori Eradication

Jun TY, Kim SH, Kim OG, Jang JG, Nor JH, Song WI, Lee JS

A 29-year-old man with nodular gastritis diagnosed by previous gastroscopy was referred to our hospital for an evaluation of laryngeal discomport and soreness. The patient had no previous history of...
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Does Age at Onset of First Major Depressive Episode Indicate the Subtype of Major Depressive Disorder?: The Clinical Research Center for Depression Study

Park SC, Hahn SW, Hwang TY, Kim JM, Jun TY, Lee MS, Kim JB, Yim HW, Park YC

PURPOSE: The purpose of this study was to evaluate the effects of age at onset of the first major depressive episode on the clinical features of individuals with major depressive...
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Korean Pharmacological Treatment Guideline for Child-Adolescent Depression: The Efficacy and Choice of Antidepressant

Song HR, Lee YH, Yang S, Lee JY, Jang JW, Jeong S, Jeong H, Jo SJ, Yim HW, Lee SY, Jun TY

OBJECTIVE: The purpose of this guideline was to suggest recommendations for appropriate use of antidepressants in the child-adolescent depression. The differences of efficacy among antidepressants were evaluated. METHODS: Four kinds of...
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