- Aberrant Promoter Methylation of the Vimentin Gene in Colorectal Cancer Associated with the Adenoma-Carcinoma Sequence
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Cho MH, Lee YM, Kim JS, Kim HS, Lee KH, Juhng SW, Lee JH
- KMID: 2277607
- Korean J Pathol.
- 2010 Apr;44(2):179-186.
BACKGROUND: DNA hypermethylation is a common epigenetic finding in human cancers and is closely associated with transcriptional silencing. In the present study, we investigated the proportion of colorectal neoplasms that... -
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- Type 3 Repeats of Thrombospondin-2 Increases Metastasis in Mouse Colorectal Cancer CT-26 Cells
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Jin Z, Kim YJ, Park YK, Choi YD, Lee JH, Lee D, Choi CY, Juhng SW, Choi C
- KMID: 2172251
- Chonnam Med J.
- 2010 Apr;46(1):7-18.
- doi: 10.4068/cmj.2010.46.1.7
Thrombospondins (TSPs) are secreted multimeric glycoproteins that modulate extracellular matrix structure and cell behaviour. TSPs are involved in platelet aggregation, cell adhesion, migration, angiogenesis, wound healing, and proliferation. The purpose... -
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- Cytologic Diagnosis of Malignant Pleural Effusion in Multiple Myeloma: Two Case Reports
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Choi YD, Kim SS, Han CW, Lee JS, Nam JH, Juhng SW, Choi C
- KMID: 2459602
- Korean J Pathol.
- 2009 Aug;43(4):382-385.
Malignant pleural effusion in multiple myeloma (MM) is extremely rare and is associated with poor prognosis. We experienced two cases of MM IgA type with malignant pleural effusion. The diagnoses... -
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- Analysis of HPV-other Samples by Performing HPV DNA Sequencing
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Choi YD, Han CW, Chung WJ, Jung WW, Lee JS, Nam JH, Lee MC, Juhng SW, Choi HS, Park CS
- KMID: 1979343
- Korean J Pathol.
- 2009 Jun;43(3):250-253.
BACKGROUND: HPV-other samples are designated as being positive on HPV-PCR, but negative when using specific HPV hybridization probes. We wanted to determine the types on the HPV-other samples by performing... -
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- DNA Methylation Profiles of MGMT, DAPK1, hMLH1, CDH1, SHP1, and HIC1 in B-Cell Lymphomas
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Kim SS, Choi YH, Han CW, Choi YD, Park Y, Lee JJ, Kim HJ, Lee IK, Lee JS, Juhng SW, Choi C
- KMID: 1472620
- Korean J Pathol.
- 2009 Oct;43(5):420-427.
- doi: 10.4132/KoreanJPathol.2009.43.5.420
BACKGROUND: This study was designed to examine the prevalence of aberrant promoter methylation in a selected panel of genes potentially involved in lymphoid tumors. METHODS: The promoter hypermethylation status of MGMT,... -
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- Association Study of hMLH1 Polymorphisms with Riskof Acute Myeloid Leukemia in Korean
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Piao CZ, Mei JX, Kim HJ, Juhng SW, Choi C
- KMID: 1973387
- Chonnam Med J.
- 2008 Apr;44(1):23-30.
- doi: 10.4068/cmj.2008.44.1.23
Acute myelogenous leukemia (AML) is caused by dysregulation of oncogenes, tumor suppressor genes, and DNA mismatch repair genes. Accumulating evidence has shown that genetic differences in mismatch repair capacity resulting... -
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- Therapeutic Effects of 1% Cyclosporin A Eyedrops on Herpetic Stromal Keratitis
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Lee KH, Park CS, Juhng SW, Woo JM, Park YG, Yoon KC
- KMID: 2172295
- Chonnam Med J.
- 2008 Dec;44(3):157-161.
- doi: 10.4068/cmj.2008.44.3.157
We evaluated the therapeutic effects of topical administration of 1% cyclosporin A on herpetic stromal keratitis. Sixteen eyes of 16 patients with non-necrotizing herpetic stromal keratitis were divided into two... -
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- Solitary Splenic Metastases from Uterine Cervical Cancer: Case Reports and Review of the Literature
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Kim JH, Choi YD, Lee JH, Nam JH, Juhng SW, Koh YS, Cho CK, Choi C
- KMID: 1163224
- Korean J Pathol.
- 2008 Oct;42(5):317-322.
Splenic metastasis from gynecologic tumors is extremely rare, especially in the absence of apparent disease at other sites. We report two patients that underwent splenectomy for a solitary splenic metastasis... -
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- An Immunohistochemical Study of Angiogenesis in Tumor Emboli
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Kim JH, Choi C, Lee JH, Lee JS, Kim SS, Han CW, Juhng SW
- KMID: 1521640
- Korean J Pathol.
- 2007 Aug;41(4):252-257.
BACKGROUND: Angiogenesis, which is essential for tumor growth, is known to occur in the extravascular stroma. However, vascular structures were noted in intravascular tumor emboli in surgical specimens. This prompted... -
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- Claudin-7 is Highly Expressed in Chromophobe Renal Cell Carcinoma and Renal Oncocytoma
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Choi YD, Kim KS, Ryu S, Park Y, Cho NH, Rha SH, Jang JJ, Ro JY, Juhng SW, Choi C
- KMID: 1713192
- J Korean Med Sci.
- 2007 Apr;22(2):305-310.
- doi: 10.3346/jkms.2007.22.2.305
Claudin-7 has recently been suggested to be a distal nephron marker. We tested the possibility that expression of claudin-7 could be used as a marker of renal tumors originating from... -
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- Tetranucleotide Repeat Microsatellite Instability in Uterine Cervical Carcinomas
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Choi YD, Lee JS, Choi C, Park CS, Juhng SW, Choi HS, Nam JH
- KMID: 1521692
- Korean J Pathol.
- 2007 Feb;41(1):30-37.
BACKGROUND: Elevated levels of microsatellite alterations at selected tetranucleotide repeat regions (EMAST) have been recently described, and they are a distinct type of microsatellite instability (MSI). We investigated the prevalence... -
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- Expression of VEGF, MMP-9 and Neovascularization in Relationship to the Clinical Behavior of Giant Cell Tumors of Bone
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Lee KH, Kim JH, Shim MK, Han CW, Kim SS, Juhng SW, Jung ST, Lee JH
- KMID: 1593778
- Korean J Pathol.
- 2006 Dec;40(6):420-426.
BACKGROUND: Giant cell tumors (GCT(s)) of bone are benign but can be locally aggressive neoplasms. Their clinical behavior has been difficult to predict on the basis of histology alone.... -
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- Relationship between Chromatin Pattern of Tumor Cell Nuclei and Transcriptional Sites
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Juhng SW
- KMID: 2172304
- Chonnam Med J.
- 2005 Dec;41(3):253-258.
Malignant cell nuclei, in general, have increased amount of heterochromatin and decreased electron density of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. Chromatin pattern in... -
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- A Case of Osteoid Osteoma of the Finger Bone
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Lee JH, Jung ST, Lee KH, Kim HJ, Oh HS, Choi YD, Nam JH, Choi C, Juhng SW
- KMID: 1613962
- Chonnam Med J.
- 2003 Sep;39(3):182-184.
The occurrence of osteoid osteoma in the hand is rare. Recently we examined a case of osteoid osteoma of distal phalanx of the middle finger in a twenty-year-old man. This... -
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- Metastatic Anaplastic Carcinoma of the Small Intestine Arising from The Lung
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Kim DY, Joo JK, Ryu SY, Kim YJ, Kim SK, Juhng SW
- KMID: 1972906
- Cancer Res Treat.
- 2003 Aug;35(4):364-366.
A metastatic carcinoma of the small intestine is rare. Here, the case study of an 80-year-old lung carcinoma patient, with generalized peritonitis due to neoplastic perforation of the small intestine... -
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- Clonal Analysis of Neurofibroma by PCR Amplification of HUMARA Gene
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Lee JH, Han SS, Oh HS, Choi YD, Kim HJ, Lee KH, Nam JH, Choi C, Juhng SW
- KMID: 1979371
- Korean J Pathol.
- 2003 Dec;37(6):421-428.
BACKGROUND: While neurofibromas have generally been regarded as polyclonal hyperplastic lesions, it remains unclear whether the tumor is a true neoplasm or a hyperplastic lesion. METHODS: Determination of clonality by... -
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- Clonality Study in Carcinosarcomas and Malignant Mixed Epithelial Tumors
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Park EJ, Choi YD, Nam JH, Lee MC, Park CS, Juhng SW, Choi IS, Kim KH, Choi C
- KMID: 1725907
- Korean J Pathol.
- 2002 Aug;36(4):205-211.
BACKGROUND: Tumors are usually considered to be clonal progeny of single transformed cells. Carcinosarcomas and malignant mixed epithelial tumors are examples where controversies exist regarding the singularity or multiplicity of... -
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- Clonality Assay of Dysplastic Epithelial Lesions of the Stomach
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Choi HS, Kim MS, Park JW, Park CS, Kim YJ, Juhng SW
- KMID: 2372683
- J Korean Gastric Cancer Assoc.
- 2001 Sep;1(3):129-135.
PURPOSE: Dysplasia or flat adenoma of the stomach is regarded as a precancerous lesion. However, the frequency and the evolutionary process of malignant transformation of gastric dysplasia are still debated.... -
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- In Situ Detection of mRNA and RNA Component of Human Telomerase in Proliferative Lesions of the Stomach
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Kim MS, Juhng SW
- KMID: 1725817
- Korean J Pathol.
- 2001 Aug;35(4):299-305.
BACKGROUND: Proliferative lesions of the stomach were investigated by in situ hybridization using RNA probes for telomerase components and compared with the results by TRAP (telomeric repeat amplification protocol) assay.... -
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- mRNA is Synthesized Mainly at the Phase between the Euchromatin and Heterochromatin: Proposal of a Phase Theory
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Kim MS, Juhng SW
- KMID: 2275638
- Korean J Pathol.
- 2001 Apr;35(2):93-97.
BACKGROUND: Malignant cell nuclei, in general, have increased amounts of heterochromatin and decreased electron densities of euchromatin, making the chromatin pattern coarser than that of benign cell nuclei. The... -
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