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Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia

Choi R, Chun MR, Park J, Lee JW, Ju HY, Cho HW, Hyun JK, Koo HH, Yi ES, Lee SY

Background: We developed an assay to measure DNA-incorporated 6-thioguanine (DNATG) and validated its clinical applicability in Korean pediatric patients with acute lymphoblastic leukemia (ALL) in order to improve individualized thiopurine...
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The comparative gene expression concern to the seed pigmentation in maize (Zea mays L.)

Sa KJ, Choi IY, Lee JK

Maize seed pigmentation is one of the important issue to develop maize seed breeding. The differently gene expression was characterized and compared for three inbred lines, such as the pigment...
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KSNR Clinical Consensus Statements: Rehabilitation of Patients with Parkinson's Disease

KSNR PD Writing Group, Kim DY, Oh HM, Bok SK, Chang WH, Choi Y, Chun MH, Han SJ, Han TR, Jee S, Jung SH, Jung HY, Jung TD, Kim MW, Kim EJ, Kim HS, Kim YH, Kim Y, Kim DY, Kim DY, Kim DK, Ko SH, Ko MH, Lee JK, Lee J, Lee SJ, Lee SG, Lim SH, Oh BM, Paik NJ, Park KD, Park SW, Park GY, Park JH, Park YG, Pyun SB, Ryu B, Seo HG, Shin YI, Sohn MK, Yang SN, Yoo SD, Yoo WK

Clinical consensus statements (CCSs) aim to improve care for patients with Parkinson's disease (PD) and reduce the variability of rehabilitation methods in clinical practice. A literature search was conducted to...
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FK506 immunosuppression for submandibular salivary gland allotransplantation in rabbit

Almansoori AA, Khentii N, Ju KW, Kim B, Kim SM, Lee JH

Objectives: We compared the outcomes of two different doses of FK506 (tacrolimus) for immunosuppression in submandibular salivary gland (SMG) allotransplantation. Materials and Methods: Three SMG allotransplantation groups were established (n=6 per...
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Efficacy of Portable Low Power Laser Therapy on Pain and Functions in Chronic Low Back Pain

Cho YW, Kim TH, Lim OK, Lee JK, Park KD

Objective: A prospective, assessor-blinded, randomized controlled trial was conducted in patients with chronic low back pain to evaluate the efficacy of portable low power laser therapy (LPLT) and the effect...
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Influence of the Perception of Aging Symptoms as a Mediator and Moderator on the Relationship between Family Function and Stress in Middle-Aged Adults

Yeom HE, Ju KO

Purpose: The purpose of this study was to investigate the roles of the perception of aging symptoms in mediating and moderating the relationship between family function and stress in middle-aged...
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Comparison of Two Static Stretching Techniques for the Triceps Surae in Healthy Individuals: Wall and Inclined Board Stretchings

Kim TH, Lim OK, Park KD, Lee JK

Objective To compare the effectiveness of static stretching techniques for correcting the tightness of the triceps surae. Methods In this observational, cross-sectional study, participants (30 healthy volunteers) completed 10 repetitions of...
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Clinical Significance of Segmental Chromosomal Aberrations in Patients with Neuroblastoma: First Report in Korean Population

Lim H, Son MH, Hyun JK, Cho HW, Ju HY, Lee JW, Yoo KH, Sung KW, Koo HH

Background This study aimed to investigate the incidence and clinical significance of segmental chromosomal aberrations (SCAs) in Korean patients with neuroblastoma. Methods Patients diagnosed with neuroblastoma from 2012 to 2018 were included for...
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A Case of Hereditary Spherocytosis Initially Manifested as an Aplastic Crisis Caused by Parvovirus B19 Infection

Jin H, Lee JW, Ju HY, Cho HW, Hyun JK, Sung KW, Koo HH, Kim HJ, Yoo KH

Hereditary spherocytosis (HS) is the most common inherited red cell membrane disorder. Its main laboratory finding is anemia with reticulocytosis. However, in the case of an aplastic crisis, there may...
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Ezrin-radixin-moesin proteins are regulated by Akt-GSK3β signaling in the rat nucleus accumbens core

Kim WY, Cai WT, Jang JK, Kim JH

The ezrin-radixin-moesin (ERM) proteins are a family of membrane-associated proteins known to play roles in cell-shape determination as well as in signaling pathways. We have previously shown that amphetamine decreases...
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Subacute Combined Degeneration Caused by Nitrous Oxide Intoxication: A Report of Two Cases

Choi C, Kim T, Park KD, Lim OK, Lee JK

We report two cases of subacute combined degeneration (SCD) caused by nitrous oxide (Nâ‚‚O) gas intoxication, which is rarely reported in Korea. Two patients recreationally inhaled Nâ‚‚O gas daily for...
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Effect of Delayed Elevation of Thyrotropin on Feeding Intolerance in Very Low Birth Weight Infants

Hyun JK, Choi SY, Jung YJ, Lee JH

PURPOSE: We investigated the effect of delayed elevation of thyrotropin (TSH) (deTSH) on gastrointestinal motility in very low birth weight infants (VLBWI). METHODS: This study retrospectively investigated 228 premature VLBWI aged...
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Perception and Satisfaction of Anticancer Drug Clinical Trials in Cancer Patients

Jeon JK, Kim JH

PURPOSE: The purpose of this study was to investigate the perception and satisfaction of cancer patients participating in clinical trials of anticancer drugs and the factors affecting their satisfaction. METHODS: The...
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Swallowed Oro-esophageal Tube: A Case Report

Kim HS, Kim TH, Lim OK, Park KD, Lee JK

Tube feeding is used to provide nutritional support to patients who have difficulty taking food orally. A nasogastric tube is commonly used for these patients but there are some complications....
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Is Immediate Postoperative Mechanical Axis Associated with the Revision Rate of Primary Total Knee Arthroplasty? A 10-Year Follow-up Study

Park JK, Seon JK, Cho KJ, Lee NH, Song EK

BACKGROUND: Achieving neutral limb alignment during total knee arthroplasty (TKA) has been considered an important determinant in the long-term prosthesis survival. The purpose of this study was to evaluate the...
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Diagnostic distal 16p11.2 deletion in a preterm infant with facial dysmorphism

Hyun JK, Jung YJ

The 16p11.2 microdeletion has been reported in patients with developmental delays and intellectual disability. The distal 220-kb deletion in 16p11.2 is associated with developmental delay, autism spectrum disorder, epilepsy, and...
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Acaulosproa koreana, a New Species of Arbuscular Mycorrhizal Fungi (Glomeromycota) Associated with Roots of Woody Plants in Korea

Lee EH, Park SH, Eo JK, Ka KH, Eom AH

A new species of arbuscular mycorrhizal fungi (Glomeromycota), Acaulospora koreana, was isolated from forest soils in South Korea. This novel fungus was collected from the rhizosphere of Lindera obtusiloba and...
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Peroxisome Proliferator-activated Receptor-gamma Inhibits the Activation of STAT3 in Cerulein-stimulated Pancreatic Acinar Cells

Ju KD, Lim JW, Kim H

Cerulein-induced pancreatitis is similar to human edematous pancreatitis, characterized by the dysregulation of digestive enzyme production, edema formation, and an infiltration of inflammatory cells into the pancreas. We previously showed...
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Comparison on the profiles of a modified Borg scale and the pediatric dyspnea scale during an induced bronchoconstriction in children with clinical asthma

Kim YS, Shin J, Choi YJ, Song JH, Lee JK, Oh HL, Suh DI, Koh YY

PURPOSE: Dyspnea is the cardinal symptom of asthma, but it is difficult to quantify clinically. Although modified Borg (mBorg) scale has been successfully used in adult, but there has been...
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Falsely Elevated Postvoid Residual Urine Volume in Uterine Myoma

Kim TH, Kim HS, Park JW, Lim OK, Park KD, Lee JK

Precise measurement of postvoid residual (PVR) urine volume is a key factor in assessing patients with voiding dysfunction, including those with lower urinary tract problems. The safe and noninvasive ultrasound...
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