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Evaluation of Reproducibility of Brain Volumetry between Commercial Software, Inbrain and Established Research Purpose Method, FreeSurfer

J, JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Background and Purpose We aimed to determine the intermethod reproducibility between the commercial software Inbrain (MIDAS IT) and the established research-purpose method FreeSurfer, as well as the effect of MRI...
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Thirty-six Year Trends in Mortality from Diseases of Circulatory System in Korea

Baek J, Lee H, Lee HH, Heo JE, Cho SMJ, Kim HC

Background and Objectives: Understanding the trends in cardiovascular disease (CVD) mortality is important for developing burden reduction strategies. Based on the Cause of Death Statistics, we examined the changing patterns...
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Effects of the fermented Zizyphus jujuba in the amyloid β25-35 -induced Alzheimer's disease mouse model

Kim MJ, Jung JE, Lee S, Cho EJ, Kim HY

BACKGROUD/OBJECTIVES: Alzheimer's disease (AD) is the most common cause of dementia in the elderly. Due to the increased incidence of dementia, there is a corresponding increase concerning the importance of...
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Comparison of Automated Brain Volume Measures by NeuroQuant vs. Freesurfer in Patients with Mild Cognitive Impairment: Effect of Slice Thickness

Yim Y, Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Purpose: This study aimed to examine the inter-method reliability and volumetric differences between NeuroQuant (NQ) and Freesurfer (FS) using T1 volume imaging sequence with different slice thicknesses in patients with...
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Comparison of response to LPS-induced sepsis in three DBA/2 stocks derived from different sources

Park JW, Lee SJ, Kim JE, Kang MJ, Bae SJ, Choi YJ, Gong JE, Kim KS, Jung YS, Cho JY, Choi YS, Hwang DY, Song HK

Sepsis, one of the most fatal diseases in the world, is known to culminate in multiple organ failure due to an uncontrolled inflammatory response. Hence, the use of animal models...
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Clinically Available Software for Automatic Brain Volumetry: Comparisons of Volume Measurements and Validation of Intermethod Reliability

Lee JY, Oh SW, Chung MS, Park JE, Moon Y, Jeon HJ, Moon WJ

Objective: To compare two clinically available MR volumetry software, NeuroQuant® (NQ) and Inbrain® (IB), and examine the inter-method reliabilities and differences between them. Materials and Methods: This study included 172 subjects...
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Oleanolic Acid Protects the Skin from Particulate Matter-Induced Aging

Kim YJ, Lee JE, Jang HS, Hong SY, Lee JB, Park SY, Hwang JS

The role of particulate matter (PM) in health problems including cardiovascular diseases (CVD) and pneumonia is becoming increasingly clear. Polycyclic aromatic hydrocarbons, major components of PM, bind to aryl hydrocarbon...
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Characteristics of the Gut Microbiome of Healthy Young Male Soldiers in South Korea: The Effects of Smoking

Yoon H, Lee DH, Lee JH, Kwon JE, Shin CM, Yang SJ, Park SH, Lee JH, Kang SW, Lee JS, Kim BY

Background/Aims: South Korean soldiers are exposed to similar environmental factors. In this study, we sought to evaluate the gut microbiome of healthy young male soldiers (HYMS) and to identify the...
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Single Cell Transcriptomic Re-analysis of Immune Cells in Bronchoalveolar Lavage Fluids Reveals the Correlation of B Cell Characteristics and Disease Severity of Patients with SARS-CoV-2 Infection

Kim CW, Oh JE, Lee HK

The coronavirus disease 2019 (COVID-19) pandemic (severe acute respiratory syndrome coronavirus 2) is a global infectious disease with rapid spread. Some patients have severe symptoms and clinical signs caused by...
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Association between Cumulative Fluid Balance and Outcomes in Acute Respiratory Distress Syndrome Patients Treated with Extracorporeal Membrane Oxygenation

Lee JH, Won JY, Kim JE, Kim HJ, Jung JS, Son HS

Background: Extracorporeal membrane oxygenation (ECMO) has become increasingly accepted as a life-saving procedure for patients with severe acute respiratory distress syndrome (ARDS). This study investigated the relationship between cumulative fluid...
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Factors affecting home cooking behavior of women with elementary school children applying the theory of planned behavior

Kim JE

BACKGROUND/OBJECTIVES: The objective of this study was to examine factors affecting cooking behavior at home. We examined components of the theory of planned behavior, perception of cooking skills, and socio-demographic...
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Perineal Metastatic Clear Cell Renal Cell Carcinoma: A Case Report

Lee SW, Yi BH, Lee MH, Choi SY, Lee JE

Perineal involvement by metastatic renal cell carcinoma (RCC) is very rare, and there are only few reports on its radiological findings in the literature. Here, we present a case of...
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Successful Transcatheter Arterial Embolization following Diverticular Bleeding in the Third Portion of the Duodenum:A Case Report

Hong SJ, Lee SM, Choi HC, Won JH, Na JB, Kim JE, Choi HY

This is a rare case of a 73-year-old male patient who presented with hematochezia and was treated using transcatheter arterial embolization following upper gastrointestinal bleeding in the third portion of...
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Introduction to the human disease resource search and distribution platform through the Korea Biobank Network portal

Kim YH, Cha HR, Lee JE, Cha SE, Choi YJ

Human-derived materials are a crucial element of research in the life sciences. The Korea Biobank Network (KBN) portal is a shared open platform that provides the nationʼs most extensive disease...
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Etiological Distribution and Morphological Patterns of Granulomatous Pleurisy in a Tuberculosis-prevalent Country

Lee J, Park S, Park JE, Choi SH, Seo H, Yoo SS, Lee SY, Kim YK, Cha SI, Park JY, Park TI, Kim CH

The cause of epithelioid granulomatous inflammation varies widely depending on the affected organ, geographic region, and whether the granulomas morphologically contain necrosis. Compared with other organs, the etiological distribution and...
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Association between Harms from the Alcohol Consumption of Others and Depression, Stress among Korean Adults

Kim JE, Chang J, Kim SJ

Background: The purpose of this study is to investigate association between harms from the alcohol consumption of others and depression measured by Patient Health Questionnaire-9, perceived stress among Korean adults. Methods:...
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Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment

Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY

Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin...
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Medical students’ perspectives on recommencing clinical rotations during coronavirus disease 2019 at one institution in South Korea

Park J, Park H, Lim JE, Rhim HC, Lee YM

Purpose: Clinical rotations of medical students across the world have inevitably been affected due to the coronavirus disease 2019 (COVID-19) pandemic. The aims of this study were to explore medical...
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Dasatinib Inhibits Lyn and Fyn Src-Family Kinases in Mast Cells to Suppress Type I Hypersensitivity in Mice

Lee D, Park YH, Lee JE, Kim HS, Min KY, Jo MG, Kim HS, Choi WS, Kim YM

Mast cells (MCs) are systemically distributed and secrete several allergic mediators such as histamine and leukotrienes to cause type I hypersensitivity. Dasatinib is a type of anti-cancer agent and it...
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Factors Related to Motor Subtypes of Delirium Patients in a Surgical Intensive Care Unit

Park SH, Kim HJ, Choi HY, You JE, Park JE, Kim EJ, Lim SJ

Purpose: The purpose of this study was to investigate the motor subtypes of delirium in patients in a Surgical Intensive Care Unit (SICU), and identify the factors related to the...
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