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Increased 1-Deoxysphingolipids and Skin BarrierDysfunction in the Skin of X-ray or Ultraviolet BIrradiation and Atopic Dermatitis Lesion Could BePrevented by Moisturizer with Physiological LipidMixture

Chung BY, Kim HO, Kang SY, Jung MJ, Kim SW, Yoo KS, Shin KO, Jeong SK, Park CW

Background: Skin diseases characterized by epithelial barrierdysfunction show altered sphingolipid metabolism,which results in changes in the stratum corneum intercellularlipid components and structure. Under pathological conditions,1-deoxysphingolipids form as atypical sphingolipidsfrom de...
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Current Status and Future Strategies to Treat Spinal Cord Injury with Adult Stem Cells

Jeong SK, Choi I, Jeon SR

Spinal cord injury (SCI) is one of the most devastating conditions and many SCI patients suffer neurological sequelae. Stem cell therapies are expected to be beneficial for many patients with...
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Clinical features and risk factors for missed stroke team activation in cases of acute ischemic stroke in the emergency department

Byun YH, Hong SY, Woo SH, Kim HJ, Jeong SK

OBJECTIVE: Acute ischemic stroke (AIS) requires time-dependent reperfusion therapy, and early recognition of AIS is important to patient outcomes. This study was conducted to identify the clinical features and risk...
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Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis

Lim CJ, Lee YM, Kang SG, Lim HW, Shin KO, Jeong SK, Huh YH, Choi S, Kor M, Seo HS, Park BD, Park K, Ahn JK, Uchida Y, Park K

Ultraviolet (UV) irradiation is a relevant environment factor to induce cellular senescence and photoaging. Both autophagy- and silent information regulator T1 (SIRT1)-dependent pathways are critical cellular processes of not only...
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Carotidynia presenting with acute ischemic stroke after carotid sinus massage

Kwak HS, Chung GH, Lee CH, Jeong SK, Ryu HU

Carotidynia is characterized by unilateral neck pain around the carotid artery. We describe a 50-year-old woman who presented with transient left-side weakness and right-side neck pain. She frequently massaged the...
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Association between Vitamin D Status and Risk of Peripheral Arterial Disease: The Dong-gu Study

Oh SH, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Shin MH

Low levels of vitamin D have been associated with increased cardiovascular disease risk. However, few studies have evaluated the association between vitamin D status and peripheral arterial disease (PAD). We...
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Histological Evidence of Artery to Artery Embolism from Calcified Atherosclerotic Plaque of Carotid Artery

Na SI, Ryu HU, Lee CH, Jang HS, Lee SW, Yang TH, Kwak HS, Chung GH, Jeong SK

Artery to artery embolism is one of the main causes of cerebral infarction, and it can originate from many locations. Here we report a case of cerebral infarction in which...
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Selective Cannabinoid Receptor-1 Agonists Regulate Mast Cell Activation in an Oxazolone-Induced Atopic Dermatitis Model

Nam G, Jeong SK, Park BM, Lee SH, Kim HJ, Hong SP, Kim B, Kim BW

BACKGROUND: Many inflammatory mediators, including various cytokines (e.g. interleukins and tumor necrosis factor [TNF]), inflammatory proteases, and histamine are released following mast cell activation. However, the endogenous modulators for mast...
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Antibody to FcεRIα Suppresses Immunoglobulin E Binding to High-Affinity Receptor I in Allergic Inflammation

Hong JY, Bae JH, Lee KE, Kim M, Kim MH, Kang HJ, Park EH, Yoo KS, Jeong SK, Kim KW, Kim KE, Sohn MH

PURPOSE: High-affinity receptor I (FcεRI) on mast cells and basophils plays a key role in the immunoglobulin E (IgE)-mediated type I hypersensitivity mediated by allergen cross-linking of the specific IgE-FcεRI...
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Perception and Barriers to Kangaroo-Mother Care Among Neonatal Intensive Care Unit Nurses

Jeong SK, Kim TI

PURPOSE: To investigate the perception and barriers of Kangaroo-Mother Care (KMC) among nurses in Neonatal Intensive Care Units (NICU). METHODS: Participants were 131 nurses working in NICU who completed self-report questionnaires...
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Association of APOE Genotype with Bone Mineral Density in Men and Women: The Dong-gu and Namwon Studies

Kim SA, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Kim HN, Song HR, Oh SH, Cauley JA, Shin MH

Many studies have investigated relationships between APOE genotype and bone mineral density (BMD). However, the results of these studies have been inconsistent. Few studies have been carried out in Asian...
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Clinical Characteristics and Risk Factors in Severely Injured Elderly Trauma Presenting to Emergency Department

Ahn BM, Choi SP, Park JH, Wee JH, Hong SY, Jeong SK

BACKGROUND: With increasing life expectancy, the number of injured elderly patients has been increasing. We evaluated the clinical characteristics of severely injured elderly patients who presented to the Emergency Department...
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APOE Polymorphism Is Associated with C-reactive Protein Levels but Not with White Blood Cell Count: Dong-gu Study and Namwon Study

Yun YW, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Choi SW, Kim HN, Cauley JA, Shin MH

We evaluated the association of the APOE polymorphism with serum C-reactive protein levels and white blood cell count in two large population-based studies in Korean. The datasets included the Dong-gu...
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Extra-intradural Spinal Meningioma: A Case Report

Jeong SK, Seong HY, Roh SW

Extradural spinal meningiomas are uncommon, and their pathophysiology is not entirely understood. Here, we present the case of a 49-year-old woman with low back and left leg pain of 5...
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Methylenetetrahydrofolate Reductase 677 Genotype-Specific Reference Values for Plasma Homocysteine and Serum Folate Concentrations in Korean Population Aged 45 to 74 Years: The Namwon Study

Kweon SS, Lee YH, Jeong SK, Nam HS, Park KS, Choi SW, Kim BH, Kim HN, Choi JS, Shin MH

The reference interval for plasma total homocysteine (tHcy) and serum folate concentrations were estimated. Total of 3,154 reference individuals (1,029 men and 2,125 women) were selected based on stringent exclusion...
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Association between Ischemic Stroke and Vascular Shear Stress in the Carotid Artery

Jeong SK, Lee JY, Rosenson R

BACKGROUND AND PURPOSE: Vascular shear stress is essential for maintaining the morphology and function of endothelial cells. We hypothesized that shear stress in the internal carotid artery (ICA) may differ...
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Association of oral health status and related factors with oral health impact profile (OHIP-14) among patients in a dental hospital in Gwangju, Korea

Jeong SK, Kim SH, Kim DK, Lee BJ

OBJECTIVES: The aim of this study was to determine the association between oral health status and oral health impact profile (OHIP-14) among patients undergoing treatment in a dental hospital, in...
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Association between Apolipoprotein E Polymorphism and Chronic Kidney Disease in the Korean General Population: Dong-gu Study

Choi SW, Kweon SS, Choi JS, Rhee JA, Lee YH, Nam HS, Jeong SK, Park KS, Ryu SY, Kim HN, Song HR, Shin MH

BACKGROUND: Few studies have investigated the association between Apolipoprotein E (APOE) polymorphisms and chronic kidney disease (CKD) in the general population, and their results are inconsistent. METHODS: The current study population...
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Gender Differences in the Association between Depressive Symptoms and Carotid Atherosclerosis among Middle-Aged and Older Koreans: The Namwon Study

Lee YH, Shin MH, Choi JS, Nam HS, Jeong SK, Park KS, Choi SW, Kweon SS

We investigated the association of depressive symptoms with carotid intima-media thickness (IMT) and plaques in the general Korean population. A total of 7,554 Korean males and females aged 45-74 yr...
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A Suggestion of Modified Classification of Trigeminal Schwannomas According to Location, Shape, and Extension

Jeong SK, Lee EJ, Hue YH, Cho YH, Kim JH, Kim CJ

BACKGROUND: Comprehensive knowledge of the anatomical features of trigeminal schwannomas (TSs) is essential in planning surgery to achieve complete tumor resection. In the current report, we propose a modified classification...
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