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Efficacy and Safety of DWJ1252 Compared With Gasmotin in the Treatment of Functional Dyspepsia: A Multicenter, Randomized, Double-blind, Active-controlled Study

Park JH, Lee KN, Lee OY, Choi MG, Chung H, Choi SC, Kim N, Park H, Sung IK, Sohn CI, Jee SR, Jang JY, Rhee PL, Park MI, Kwon JG, Park KS, Lee KJ, Lee JS

  • KMID: 2510066
  • J Neurogastroenterol Motil.
  • 2021 Jan;27(1):87-96.
  • doi: 10.5056/jnm20061
Background/Aims Prokinetics such as mosapride citrate CR (conventional-release; Gasmotin) are commonly used in functional dyspepsia (FD). This study aims to evaluate the efficacy and safety of once-a-day mosapride citrate SR (DWJ1252),...
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Protective Effect of Rice Bran Oil against β-Amyloid Protein-Induced Memory Impairment and Neuronal Death in Mice

Jang JY, Lee HK, Yoo HS, Seong YH

This study was undertaken to investigate the protective effect of rice bran oil (RBO) on amyloid β protein (Aβ) (25-35)-induced memory impairment and brain damage in an ICR mouse model....
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Effectiveness of a multidisciplinary team for nutrition support in a trauma intensive care unit

Oh E, Shim H, Yon HJ, Moon JS, Kang DR, Jang JY

Background: We evaluated clinical and nutritional outcomes according to multidisciplinary team involvement in nutrition support in a regional trauma intensive care unit (TICU). Methods: We retrospectively compared the outcomes for 339...
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Preliminary Clinical Trial of Balance Compensation System for Improvement of Balance in Patients With Spinocerebellar Ataxia

Hong JS, Kim JH, Yong SY, Lee YH, Kim SH, Park JY, Lee JK, Jang JY

Objective To determine the immediate and short-term impact of the application of wearable balance compensation system (BCS) on balance impairment in patients with spinocerebellar ataxia (SCA). Methods The study enrolled 6...
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Entecavir+tenofovir vs. lamivudine/telbivudine+adefovir in chronic hepatitis B patients with prior suboptimal response

Woo HY, Park JY, Bae SH, Kim CW, Jang JY, Tak WY, Kim DJ, Kim IH, Heo J, Ahn SH

Background/Aims: Suboptimal responses to lamivudine or telbivudine plus adefovir (LAM/LdT+ADV) rescue therapy are common in patients with LAM-resistant hepatitis B virus (HBV) infections. We compared patients switched to entecavir plus...
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Clinical application of ultrasonography-guided percutaneous liver biopsy and its safety over 18 years

Chang Y, Kim JI, Lee B, Kim SG, Jung MJ, Kim YS, Jeong SW, Jang JY, Yoo JJ

Background/Aims: Liver biopsy (LB) remains the gold standard for the evaluation of liver disease. However, over the past two decades, many noninvasive tests have been developed and utilized in clinical...
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The Implication of Cytogenetic Alterations in Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm Identified by Fluorescence In Situ Hybridization and Their Potential Diagnostic Utility

Lim CS, Im K, Lee DS, Kwon W, Kim JR, Han Y, Kim SW, Jang JY

Background/Aims: We investigated chromosomal aberrations in patients with pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasm (IPMN) by fluorescence in situ hybridization (FISH) to identify cytogenetic changes and molecular...
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Excision Can Be Delayed until Size Grows in Small Papillary Lesions of the Breast

Jang JY, Kim I, Lee SA, Kim SK

Purpose: The management of intraductal papilloma (IDP) without atypia remains controversial. This study evaluated the manifestations and incidence of malignancy during observation without surgery in patients diagnosed with IDP by...
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Comparison of clinical outcomes according to the history of previous gastrectomy in patients undergoing pancreatoduodenectomy: a propensity score matching analysis

Kim JR, Kwon W, Chang J, Jang JY, Kim SW

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A Case Report on the Dermoscopic Features of Spark’s Nevus

Park JB, Seong SH, Jang JY, Yang MH, Suh KS, Jang MS

Spark’s nevus is a compound word composed of Spitz nevus and Clark’s nevus. It is one of the combined melanocytic nevi which is more common in female and usually presents...
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A Case of Secretory Carcinoma of the Soft Palate

Lee JH, Ha JH, Jang JY

Secretory carcinoma of salivary gland origin is a recently described tumor that harbors a characteristic ETV6-NTRK3 translocation that is identical to secretory carcinoma of the breast. The majority of tumors...
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Clinicoradiological features of resected serous cystic neoplasms according to morphological subtype and preoperative tentative diagnosis: can radiological characteristics distinguish serous cystic neoplasms from other lesions?

Kang JS, Kim HJ, Choi YJ, Byun Y, Lee JM, Han Y, Kim H, Kwon W, Jang JY

Purpose: Serous cystic neoplasm (SCN) of the pancreas is considered benign in most cases. However, some SCN patients undergo surgical resection because lesions could not be differentiated preoperatively. This study...
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Effects of probiotics or broccoli supplementation on Helicobacter pylori eradication with standard clarithromycin-based triple therapy

Chang YW, Park YM, Oh CH, Oh SJ, Cho JH, Kim JW, Jang JY

Background/Aims: The eradication failure rate of standard triple therapy (proton pump inhibitor, clarithromycin, and amoxicillin) for Helicobacter pylori infection has increased owing to antibiotic resistance in Korea. We assessed whether...
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Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea

Kim SK, Jang JY, Kim DL, Rhyu YA, Lee SE, Ko SH, Han K, Song KH, On behalf of the Task Force Team for Diabetes Fact Sheet of the Korean Diabetes Association

Background/Aims: We aimed to evaluate site-specific cancer risk in diabetic patients and to investigate causal and temporal relationships by analyzing organ-specific cancer risk according to the duration of diabetes. Methods: Using...
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Safety and Effectiveness of Indwelling Percutaneous Drainage in Hospitalized Terminally Ill Cancer Patients with Recurrent Ascites

Park K, Lee GW, Kim JJ, Oh SB, Oh SY, Park EJ, Kim JH, Jang JY, Jeon UB

Objectives: Terminally ill cancer patients in hospice palliative care unit are reluctant to undergo repetitive invasive procedures due to coagulopathies and poor performance or condition, while catheter management such as...
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Comparison of clinical outcomes according to the history of previous gastrectomy in patients undergoing pancreatoduodenectomy: a propensity score matching analysis

Kim JR, Kwon W, Chang J, Jang JY, Kim SW

Purpose: Although pancreatoduodenectomy (PD) in patients who have previously undergone gastrectomy is challenging, little is known about the clinical outcomes and the differences compared to those with conventional PD. We...
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Resuscitative Endovascular Balloon occlusion of the aorta in Impending Traumatic arrest: Is It Effective?

Chung JS, Kim OH, Kim S, Jang JY, An GJ, Jung PY

Purpose Hemorrhagic shock is the leading cause of death in trauma patients worldwide. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a technique used to improve the hemodynamic stability of...
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Emphysematous Gastritis Worsened after Upper Endoscopy

Kim TU, Kim SJ, Ryu H, Kim JH, Jang JY, Yeom JA, Roh J, Jeong HS, Park BS, Kim DI

Emphysematous gastritis is an infectious disease in which air is formed in the gastric wall by gas-forming organisms. It is infrequently reported but can be fatal without early diagnosis and...
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Roles of Tumor Markers in Diagnosis and Treatment of Hepatocellular Carcinoma

Chang Y, Jang JY

There are a wide variety of tumor markers for hepatocellular carcinoma (HCC). Studies are ongoing regarding the roles of tumor markers in screening, diagnosis, treatment, and prognostic prediction of HCC....
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A Study on Concentration, Identification, and Reduction of Airborne Microorganisms in the Military Working Dog Clinic

Kim MH, Baek KO, Park GG, Jang JY, Lee JH

Background The study was planned to show the status of indoor microorganisms and the status of the reduction device in the military dog clinic. Methods Airborne microbes were analyzed according to the number...
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